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    Review

    Exploring the Therapeutic Potential of Natural Products in Obesity Treatment: Molecular Mechanisms and Isolation Techniques

    Sandhya Jaiswal1★, Aaditee Sharma1, Anjoo Kamboj2, Jaspreet Kaur3, Parminder Nain4★ Corresponding author

    1. 1Department of Pharmaceutics, Chandigarh College of Pharmacy, Landran, Mohali, Punjab, INDIA.
    2. 2Department of Pharmaceutical Chemistry, Chandigarh College of Pharmacy, Landran, Mohali, Punjab, INDIA.
    3. 3Department of Pharmacognosy, School of Pharmaceutical Sciences, RIMT University, Mandi-Gobindgarh, Punjab, INDIA.
    4. 4Department of Pharmacy Practice, School of Pharmaceutical Sciences, RIMT University, Mandi-Gobindgarh, Punjab, INDIA.

    CORRESPONDENCE

    Sandhya Jaiswal

    Department of Pharmaceutics, Chandigarh College of Pharmacy, Landran, Mohali-140307, Punjab, INDIA.

    sandhya@cgc.edu.in

    Received: 24-09-2024; Revised: 15-11-11; Accepted: 09-01-2025.

    Volume 17, Issue 2 · pp. 358–369 · PUBLISHED 2025 · DOI: 10.5530/pres.20252016

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    The present review focuses on the investigation of natural chemical constituents that contribute to anti-obesity activity, along with their mechanisms of action and potential therapeutic applications. Extensive literature searches from reputed and indexed journal data sets were performed. Review highlights bioactive compounds derived from various plants and natural sources that show promising anti-obesity properties. Resolving the complexity of mechanisms by which these bioactive components function provides a valuable insight for the development of innovative interventions in obesity management, ultimately promoting complete wellness. This review emphasizes the significance of understanding and utilizing the potential of naturally occurring substances to fight against obesity and to find a way for novel therapeutic strategies. The identification of head compounds and their anti-obesity properties not only broadens the understanding of physiological processes but also offers a structure for the advancement of targeted and effective interventions. This comprehensive analysis contributes to the ongoing discussion on anti-obesity approaches, emphasizing the role of natural compounds as potential agents for improving obesity-related challenges. This review will serve as a platform for researchers and health practitioners in the further search of developing evidence-based strategies for obesity management, aligning with the pattern shift towards integrative and nature-inspired healthcare solutions.

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      Jaiswal, S., Sharma, A., Kamboj, A., Kaur, J., & Nain, P. (2025). Exploring the Therapeutic Potential of Natural Products in Obesity Treatment: Molecular Mechanisms and Isolation Techniques. Pharmacognosy Research, 17(2), 358–369. https://doi.org/10.5530/pres.20252016