Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Free Radicals and AntioxidantsNOW IN
    Article

    Studies on Phytochemical Constituents, Quantification of Total Phenolic, Alkaloid Content and In-vitro Anti-oxidant Activity of Thespesia populnea Seeds

    Ganga Rao. B1, Umamaheswara Rao. P1★, Sambasiva Rao. E1, Mallikarjuna Rao. T1, V.S.Praneeth. D1★ Corresponding author

    1. 1A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam530003, A.P, India.

    CORRESPONDENCE

    Umamaheswara Rao. P

    A.U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam530003, A.P, India.

    umaphd2011@gmail.com

    Volume 1, Issue 4 · pp. 56–61 · PUBLISHED · DOI: 10.5530/ax.2011.4.9

    View on Free Rad. Antiox. original site ↗

    ABSTRACT

    Introduction: Anti-oxidants are vital substances which possess the ability to protect the body from damage caused by free radical induced oxidative stress. There is an increasing interest in natural anti-oxidants, e.g., polyphenols, present in medicinal and dietary plants, which might help prevent oxidative damage. Methods: In this present study we investigated preliminary phytochemical, total phenolic, alkaloid content and In-vitro antioxidant activity of hexane, ethyl acetate, ethanol (70%) and methanol extracts of Thespesia populnea Seeds. Results:Thespesia populnea Seeds revealed the presence of steroids, flavonoids and alkaloids, glycosides, tannins, quinones and carbohydrates. The extracts do not contain the amino acids, oils and the hexane fraction do not contain triterpenes and tannins. The ethyl acetate extract have more phenolic content than other extracts and the methanolic extract has more alkaloidal than other extracts. The selected plant extracts were produced concentration dependent percentage inhibition of superoxide radical and produced maximum activity at a concentration of 160 µg and there after the percentage inhibition were raised gradually to its maximum level with higher concentrations. Conclusion: Among the four types of T.populnea seeds extracts, the methanolic extract showed better activity than aqueous extracts at 160 µg concentrations.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      B, G. R., P, U. R., E, S. R., T, M. R., & D, V. (). Studies on Phytochemical Constituents, Quantification of Total Phenolic, Alkaloid Content and In-vitro Anti-oxidant Activity of Thespesia populnea Seeds. Free Radicals and Antioxidants, 1(4), 56–61. https://doi.org/10.5530/ax.2011.4.9