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    Free Radicals and AntioxidantsNOW IN
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    Potential Antioxidant and Antibacterial Properties of Medicinal Plant Trachyspermum ammi L. Seeds

    Ravi Sahukari1, Jyothi Punabaka1, Praveen Kumar Yamala2, Shanmugam Bhasha1, Venkata Subbaiah Ganjikunta1, Sathyavelu Reddy Kesireddy1★★ Corresponding author

    1. 1Department of Zoology, Sri Venkateswara University, Tirupati, Andhra Pradesh, INDIA..
    2. 2Department of Microbiology, Sri Venkateswara University, Tirupati, Andhra Pradesh, INDIA..

    CORRESPONDENCE

    Sathyavelu Reddy Kesireddy

    Department of Zoology, Sri Venkateswara University, Tirupati, Andhra Pradesh, INDIA..

    sravijpl@gmail.com

    Received: 21-10-2020; Revised: 29-11-2020; Accepted: 12-12-2020.

    Volume 10, Issue 2 · pp. 56–62 · PUBLISHED · DOI: 10.5530/fra.2020.2.11

    View on Free Rad. Antiox. original site ↗

    ABSTRACT

    Background: A highly valued medicinal plant belonging to the family Apiaceaeis Trachyspermum ammi L. The seeds of this plant are used as spice and are traditionally used for the treatment of many human and animal illnesses. Objectives:In this research study, we aimed at quantitatively estimating the phytochemicals, antioxidant and antimicrobial activity of different solvent extracts of T. ammi seeds. Methods:Quantification of phenol and flavonoid phytochemicals have been estimated in different solvent extracts of seeds. Further, the antioxidant activity was determined by performing DPPH, lipid peroxidation, reducing capacity and total antioxidant activity assays. Additionally, antibacterial activity was assessed against three bacterial species using well-diffusion method.Results: The findings showed in quantitative estimation that phenols and flavonoids were rich in extracts. Acetone, Methanol and Ethanol extracts were potentially scavenged DPPH radical, lipid peroxidation nullified and metal ions such as Fe and Mo reduced. At the same time, effective antibacterial activity on E. coli, S. aureus and Pseudomonasbacterial species was seen in Chloroform and Methanol extracts and synthesized silver nanoparticles.Conclusion:In conclusion, free radical scavenging, reduction of metals and antibacterial activity of different extracts of T. ammiwas indicative of the presence of enormous amounts of phenols and flavonoids. Further work on these extracts needs to be done to isolate the active compounds and, to treat free radicals and related bacterial diseases.

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      Sahukari, R., Punabaka, J., Yamala, P. K., Bhasha, S., Ganjikunta, V. S., & Kesireddy, S. R. (). Potential Antioxidant and Antibacterial Properties of Medicinal Plant Trachyspermum ammi L. Seeds. Free Radicals and Antioxidants, 10(2), 56–62. https://doi.org/10.5530/fra.2020.2.11