Phcog.Net logo
Submit

BROWSE ALL JOURNALS

    SEE ALL 6 JOURNALS
    Free Radicals and AntioxidantsNOW IN
    Article

    Dietary Chlorella vulgaris Supplementation Improves Reproductive Index of Female Rabbits and Protect their Progeny against Oxidative Stress

    Akeem Babatunde Sikiru1,2, Arunachalam Arangasamy2★, Iyabo Comfort Alemede1, Sellappan Selvaraju2, Stephen S Acheneje Egena1, Bala Krishnan Binsila2, Ippala Janardhan Reddy3, Raghavendra Bhatta4★ Corresponding author

    1. 1Department of Animal Production, Federal University of Technology, Minna, NIGERIA.
    2. 2Reproductive Physiology Laboratory, ICAR-National Institute of Animal Nutrition and Physiology, Bangalore, Karnataka, INDIA.
    3. 3Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Bangalore, Karnataka, INDIA.
    4. 4ICAR-National Institute of Animal Nutrition and Physiology, Bangalore, Karnataka, INDIA.

    CORRESPONDENCE

    Arunachalam Arangasamy

    Reproductive Physiology Laboratory, ICAR-National Institute of Animal Nutrition and Physiology, Bangalore, Karnataka, INDIA.

    arangasamyars@gmail.com

    Received: 02-08-2022; Revised: 16-08-2022; Accepted: 27-08-2022.

    Volume 12, Issue 2 · pp. 55–62 · PUBLISHED · DOI: 10.5530/fra.2022.2.10

    View on Free Rad. Antiox. original site ↗

    ABSTRACT

    Background:Oxidative stress negatively impacts pregnancy and its outcomes; hence, its avoidance through gestational antioxidant intakes is a desired nutrition-reproduction practices. Materials and Methods: Female rabbits (n=40) were divided into 5 groups and supplemented with 0, 200, 300, 400, and 500 mg Chlorella vulgaris biomass per kilogram body weight daily, respectively throughout the gestation period. Upon kindling, kits of the female rabbits (n=75) were randomly selected and monitored from birth till 120 days old. The reproductive performance of the female rabbits was evaluated by computation of their reproductive index, while birth weight, growth rate, oestrogen and testosterone concentrations, oxidative stress biomarkers, and expression of selected functional genes of the progeny were determined. Results:The gestational intake of Chlorella vulgaris increased reproductive index of the female rabbits (p < 0.05), and it also increases the growth and oxidative stress protection status of the rabbit progeny (p < 0.05). Selected functional genes, including Gstp1, Cyp1a1, Ar, Ghr, Il2, and Il6 assessed in the progeny of the supplemented groups were significantly upregulated (p < 0.05). Conclusion: It was concluded from these results that gestational Chlorella vulgaris biomass intake improved reproductive index of the female rabbits, increased growth and oxidative stress protection in their progeny.

    KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Sikiru, A. B., Arangasamy, A., Alemede, I. C., Selvaraju, S., Egena, S. S. A., Binsila, B. K., Reddy, I. J., & Bhatta, R. (). Dietary Chlorella vulgaris Supplementation Improves Reproductive Index of Female Rabbits and Protect their Progeny against Oxidative Stress. Free Radicals and Antioxidants, 12(2), 55–62. https://doi.org/10.5530/fra.2022.2.10