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    Free Radicals and AntioxidantsNOW IN
    Phcog.Net FREE RADICALS AND ANTIOXIDANTS Volume 1 · Issue 3 · pp. 1–101
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    Cover: Free Radicals and Antioxidants

    Free Radicals and Antioxidants

    Volume 1, Issue 3

    · pp. 1–101 · 13 articles

    Volume
    1
    Issue
    3
    Published
    Pages
    1–101
    Articles
    13
    Sections
    1
    ISSN
    2231-2536
    Journal
    Free Rad. Antiox.

    In this issue

    1. Article

      Diabetes Mellitus and Oxidative Stress in the Gastrointestinal Tract-Connecting the Dots

      Subhankar Chakraborty

      pp. 1–2 · DOI: 10.5530/ax.2011.3.1 · Published

      Diabetes mellitus is a global epidemic. In the United States alone, the National Diabetes Information Clearinghouse (NDCI), a joint service of the National Institute of Diabetes and Digestive and Kidney Diseases and the …

    2. Article

      Assessment of tumor Prevention in type 1 neurofibromatosis using a nitroxide compound

      Jad El-Hoss, Aaron S. Micallef, Kathryn E. Fairfull-Smith, Steven E. Bottle, David G. Little, Aaron Schindeler

      pp. 13–18 · DOI: 10.5530/ax.2011.3.3 · Published

      Background:Type 1 Neurofibromatosis (NF1) is a genetic disorder linked to mutations of the NF1 gene. Clinical symptoms are varied, but hallmark features of the disease include skin pigmentation anomalies (café au lait ma…

    3. Article

      Superoxide dismutase Ameliorates the Bowel Alterations Induced by diabetes Mellitus – An Experimental Study

      Henrique Fillmann, Juliana Tieppo, Nélson Alexandre Kretzmann Filho, Graziella Rodrigues, Jaqueline Nascimento Picada, Julian Panés, Norma Possa Marroni

      pp. 19–26 · DOI: 10.5530/ax.2011.3.4 · Published

      Introduction:The gastrointestinal system is frequently affected in patients with diabetes mellitus (DM). Some of these alterations are due to oxidative stress and the production of free radicals. The present study was de…

    4. Article

      under Increased Hydrogen Peroxide conditions, the Antioxidant Effects of Pequi oil (Caryocar brasiliense camb.) to decrease dnA damage in runners are Influenced by Sex, Age and oxidative Stress-related Genetic Polymorphisms

      Ana Luisa Miranda-Vilela, Penha Cristina Zaidan Alves, Arthur Kenji Akimoto, Graciana Souza Lordelo, Maria de Nazaré Klautau-Guimarães, Cesar Koppe Grisolia

      pp. 27–39 · DOI: 10.5530/ax.2011.3.5 · Published

      Context:Exhausting exercise, increasing reactive oxygen species, can overwhelm the endogenous antioxidant system’s capacity, resulting in oxidative damage to DNA. Deficient antioxidant defenses, influenced by certain gen…

    5. Article

      Regulation of Membrane Unsaturation as Antioxidant Adaptive Mechanism in Long-lived Animal Species

      Alba Naudí, Mariona Jové, Victòria Ayala, Manuel Portero-Otín, Gustavo Barja, Reinald Pamplona

      pp. 3–12 · DOI: 10.5530/ax.2011.3.2 · Published

      Oxidative stress resulting from biomolecular oxidative damage due to the imbalance between reactive species production and antioxidant response has become an universal constraint of life-history evolution in animals and …

    6. Article

      Electrophilic, Free radical and reactive oxygen Species Scavenging and detoxification Potentials of Lophiraalata Stem Bark Extract

      Taofeek Olakunle Ajiboye, Musa Toyin Yakubu, Adenike Temidayo Oladiji

      pp. 40–47 · DOI: 10.5530/ax.2011.3.6 · Published

      The electrophilic, free radical and reactive oxygen species scavenging and detoxification potentials of Lophiraalata stem bark was evaluated. L. alata stem bark effectively scavenged DPPH radical, superoxideion and hydro…

    7. Article

      Antimicrobial and Antioxidant Activities of Polyphenols against Streptococcus mutans

      Varunraj Sendamangalam, One Kyun Choi, Youngwoo Seo, Don-Shik Kim

      pp. 48–55 · DOI: 10.5530/ax.2011.3.7 · Published

      Natural polyphenols, gallic acid, tannic acid, quercetin and salicylic acid, were investigated for their antimicrobial and antioxidant activities against Streptococcus mutans. Ascorbic acid, well known for its antimicrob…

    8. Article

      Antiproliferative Effect of Antioxidative Free and Bound Phenolics from Andrographis serpyllifolia

      Smitha Jayaram, Shylaja M. Dharmesh

      pp. 56–65 · DOI: 10.5530/ax.2011.3.8 · Published

      Background:Andrographis serpyllifolia, used as a medicinal plant in traditional practices in India, where in cancer patients are treated using the leaves of A. serpyllifolia. The crude extracts of A. serpyllifolia not on…

    9. Article

      Phytochemical Screening and In-vitro Evaluation of Antioxidant Activity and Antimicrobial Activity of the Leaves of Sesbania sesban (L) Merr.

      Mani RP, Pandey Awanish, Goswami Shambaditya, Tripathi Poonam, Kumudhavalli V, Singh Ajay Pratap

      pp. 66–69 · DOI: 10.5530/ax.2011.3.9 · Published

      Introduction:Antioxidants are micronutrients that have gained importance in recent years due to their ability to neutralize free radicals or their actions. Sesbania sesban (L) Merr is an ancient plant which is traditiona…

    10. Article

      Free Radical Scavenging and Anti-lipid Peroxidative Effects of a Hydro-ethanolic Extract of the Whole Plant of Synedrella nodiflora (L.) Gaertn (Asteraceae)

      Patrick Amoateng, George Assumeng Koffuor, Kwame Sarpong, Kwabena Oteng Agyapong

      pp. 70–78 · DOI: 10.5530/ax.2011.3.10 · Published

      Background:Synedrella nodiflora (L.) Gaertn. (Asteraceae), a native Ghanaian shrub, has been used for the treatment of epilepsy, hiccup and threatened abortion. The present study aimed at investigating the possible mecha…

    11. Article

      In vitro Antioxidant Activity and Phytochemical Screening of Endophytic Extracts of Crotalaria pallida

      Govindappa M, Bharath N, Shruthi HB, Gustavo Santoyo

      pp. 79–85 · DOI: 10.5530/ax.2011.3.11 · Published

      Introduction: The species Crotalaria pallida, which belongs to the Fabaceae family (Sub-family Faboideae), the members of which are herbs, shrubs and trees found in both temperate and tropical areas. All parts of the pla…

    12. Article

      Radical Scavenging and Antioxidant Activity of Carthamus tinctorius Extracts

      Rajesh Mandade, S.A. Sreenivas, Avijit Choudhury

      pp. 87–93 · DOI: 10.5530/ax.2011.3.12 · Published

      Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation, and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. In the present …

    13. Article

      Attenuation of Oxidative Damage in Alloxan Induced Diabetic Rabbits Following Administration of the Extract of the Leaves of Vernonia amygdalina.

      Owolabi, MA, Jaja, SI, Olatunji, OJ, Oyekanmi, OO, Adepoju, S

      pp. 94–101 · DOI: 10.5530/ax.2011.3.13 · Published

      Introduction: Diabetes is a disease that constitutes multiple sources of free radicals, thus oxidative stress is expected to have a double impact. Since oxidative stress is mediated by hyperglycemia-induced generation of…