Ticagrelor-Induced Complete Heart Block: A Rare Entity
Wagle Varun Anand1, Isha Khadke1★, R Padmakumar2, M Sudhakar Rao2, Bharti Chogtu1★ Corresponding author
- 1Department of Pharmacology Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
- 2Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
CORRESPONDENCE
Isha Khadke
Department of Pharmacology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal - 576 104, Karnataka, India.
Received: 14-12-2019; Revised: 17-04-2020; Accepted: 28-07-2020.
Volume 11, Issue 2 · pp. 75–7 · PUBLISHED 21 October 2020 · DOI: 10.4103/jpp.JPP_121_19
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ABSTRACT
Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle branch block who was prescribed ticagrelor post angioplasty. Electrocardiogram (ECG) revealed a complete heart block after about 1 week. Ticagrelor was stopped and replaced by clopidogrel. The patient became asymptomatic and ECG showed baseline rhythm after 1 week of stoppage of ticagrelor.
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Anand, W. V., Khadke, I., Padmakumar, R., Rao, M. S., & Chogtu, B. (2020). Ticagrelor-Induced Complete Heart Block: A Rare Entity. Journal of Pharmacology and Pharmacotherapeutics, 11(2), 75–7. https://doi.org/10.4103/jpp.JPP_121_19