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    Phcog.Net JOURNAL OF PHARMACOLOGY AND PHARMACOTHERAPEUTICS Volume 11 · Issue 2 21 October 2020 · pp. 35–85
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    Cover: Journal of Pharmacology and Pharmacotherapeutics

    Journal of Pharmacology and Pharmacotherapeutics

    Volume 11, Issue 2

    21 October 2020 · pp. 35–85 · 10 articles

    Volume
    11
    Issue
    2
    Published
    21 October 2020
    Pages
    35–85
    Articles
    10
    Sections
    4
    ISSN
    ISSN: Print - 0976-500X, Online - 0976-5018
    Journal
    J Pharmacol. Pharmacother.
    Review ArticleResearch PaperCase ReportResearch Letter

    In this issue

    Review Article

    1. Review

      Linagliptin: Cardiovascular and Renal Safety beyond Doubt at a Steep Price

      Shubham Atal, Zeenat Fatima, Sadasivam Balakrishnan, Rajnish Joshi

      pp. 35–43 · DOI: 10.4103/jpp.JPP_10_20 · Published 21 October 2020

      Dipeptidyl peptidase-IV inhibitors or “gliptins” are commonly used oral anti-diabetic drugs for Type 2 diabetes mellitus, preferred as add-on therapy after metformin. Various cardiovascular outcome trials (CVOTs) have es…

    Research Paper

    1. Article

      Curcumin Improves the Behavior and Memory in Mice by Modulating the Core Circadian Genes and Their Associated Micro-RNAs

      Dhondup Namgyal, Kumari Chandan, Sher Ali, Rachna Mehta, Maryam Sarwat

      pp. 44–52 · DOI: 10.4103/jpp.JPP_86_20 · Published 2020

      Objective: To investigate the neuroprotective effects of curcumin in albino mice focusing on memory and behavior. Materials and Methods: Four groups of 7 mice each, different concentrations of curcumin were administered …

    2. Article

      Potentially Inappropriate Medications in Indian Geriatric Patients Visiting Out-patient Departments of Tertiary Care Teaching Hospital

      Maulik M. Patel, Andrew S. Mark, Varsha J. Patel

      pp. 53–58 · DOI: 10.4103/jpp.JPP_16_20 · Published 2020

      Aim: To investigate the prevalence of potentially inappropriate medications (PIMs) identified by the American Geriatrics Society Beers 2019 criteria in geriatric patients in India. Materials and Methods: This cross-secti…

    3. Article

      Assessment of Adverse Drug Reactions in Patients on Cardiovascular Drugs: A Prospective Study

      C. Sneha, H. V. Anuradha, Ashok Karthik

      pp. 59–63 · DOI: 10.4103/jpp.JPP_106_19 · Published 21 October 2020

      Objective: To quantify ADRs in patients on cardiovascular drugs and to assess their severity. Materials and Methods: Based on inclusion and exclusion criteria, 265 inpatients on cardiovascular drugs from a tertiary care …

    4. Article

      Factors Driving Self-medication with Antimicrobials in Karaikal, Puducherry, India

      Devashree Moktan, Syed Ilyas Shehnaz

      pp. 64–71 · DOI: 10.4103/jpp.JPP_21_20 · Published 2020

      Aims: To determine factors driving individuals to self medicate with antimicrobials and to ascertain the prevalence and practice of consumption of nonprescribed antimicrobials in Karaikal district of union territory of P…

    Case Report

    1. Article

      Valproic Acid-Induced Normal Pressure Hydrocephalus in a Tertiary Care Hospital

      Samriddhi Kamath, Veena Venugopal, Kanav Khera, Shivashankar KN, B. Athira

      pp. 72–74 · DOI: 10.4103/jpp.JPP_111_19 · Published 21 October 2020

      Behavioral and psychological symptoms of dementia (BPSD) are a common psychological disorder in the geriatric population with dementia. The causes and risk factors are multiple, and they include biological, psychological…

    2. Article

      Ticagrelor-Induced Complete Heart Block: A Rare Entity

      Wagle Varun Anand, Isha Khadke, R Padmakumar, M Sudhakar Rao, Bharti Chogtu

      pp. 75–7 · DOI: 10.4103/jpp.JPP_121_19 · Published 21 October 2020

      Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Her…

    3. Article

      Intra-arterial Nimodipine Combined with Intra-arterial Milrinone for the Treatment of Cerebral Vasospasm Following Subarachnoid Hemorrhage

      Jina Raj, Vysakh Visweswaran, Remya Reghu, N. R. Sreehari

      pp. 78–80 · DOI: 10.4103/jpp.JPP_65_20 · Published 21 October 2020

      Cerebral vasospasm is a potentially devastating complication of subarachnoid hemorrhage (SAH) associated with substantial morbidity and mortality. Although various studies have separately examined the use of intra-arteri…

    4. Article

      Hypersensitivity to Aerosol Spray Dressing

      Isha Khadke, Navin Patil, Nishanth Ampar, Shalini Adiga, Shyamasunder N. Bhat

      pp. 81–82 · DOI: 10.4103/jpp.JPP_41_20 · Published 21 October 2020

      We report case of a 12-year-old girl who had undergone surgical correction for Lenke’s Type 1A right-sided adolescent idiopathic scoliosis in the spine unit of our hospital. Postoperatively, secondary suturing was requir…

    Research Letter

    1. Article

      Assessment of Adverse Drug Reactions, Severity, Preventability Status, and Its Determinants among Inpatients in Tertiary Care Hospitals in South India

      Nitin Joseph, S. M. Rakshitha, Diksha Shankar Partunor, Naisargi Bhaveshkumar Bhayani, S. D. Tejas, S. Mallik Mujawar

      pp. 83–85 · DOI: 10.4103/jpp.JPP_74_20 · Published 21 October 2020

      Sir, This observational study was done to assess the pattern of adverse drug reactions (ADRs), its severity, determinants, and preventability status among inpatients at a government and private hospital in Mangalore in M…