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    Journal of Pharmacology and PharmacotherapeuticsNOW IN
    Article

    Prevalence, Risk Factors, and Prescribing Trends in Chronic Renal Failure in the Indian Population

    Jalpa Suthar1★, Rutvi D. Patel2, Shubha Desai3★ Corresponding author

    1. 1Departments of Pharmacology and Clinical Pharmacy, Ramanbhai Patel College of Pharmacy, CHARUSAT, Changa, Gujarat, INDIA.
    2. 2Department Clinical Pharmacy, Ramanbhai Patel College of Pharmacy, CHARUSAT, Changa, Gujarat, INDIA.
    3. 3Research Department, Dr. Jivraj Mehta Smarak Health Foundation, Ahmedabad, Gujarat, India.

    CORRESPONDENCE

    Jalpa Suthar

    Department of Pharmacology and Clinical Pharmacy, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT Campus, Changa, Gujarat, India.

    jalpasuthar.ph@charusat.ac.in

    Received: 12-10-2020; Revised: 28-01-2021; Accepted: 17-03-2021.

    Volume 12, Issue 2 · pp. 86–90 · PUBLISHED 17 September 2021 · DOI: 10.4103/jpp.JPP_149_20

    View on J Pharmacol. Pharmacother. original site ↗

    ABSTRACT

    Objective: To estimate the prevalence of Chronic renal failure (CRF) in the Indian subcontinent and to identify risk factors and treatment regimens for CRF. Methods: A prospective observational study was carried out for 7 months. A total of 200 patients with a level of creatinine >1.5 mg/dl were enrolled. CRF prevalence was measured using the hospital’s inpatient department registry and medical records. The risk factors and prescribing were evaluated from the patient file report. Results: The prevalence rate of CRF was 13.7%. Male patients (59%) dominate the entire group of patients. Most patients (n = 52) were found between the age group of 71–80 years with a mean age of 62.67 ± 16.33 years. Drugs such as diuretics, and hypoglycemics were indicated to treat comorbidities. The average number of drugs per prescription were 7.43 ± 2.75 with high use of antimicrobial agents (88%). Out of 156 drugs prescribed, 76 were from essential as per essential Drug List 2017. Hypertension (P = 0.0072) and diabetes (P = 0.0084) were major concerns as risk factors followed by the drugs used for dyslipidemia, and recurrent infections. Conclusion: The prevalence rate was found to be 13.7% with significant association with risk factors such as hypertension, diabetes, and nonsteroidal anti‑inflammatory drugs, dyslipidemia, chronic infections, smoking, and renal calculus for CRF. The pattern of prescribing was suitable and with few irrationalities.

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      Suthar, J., Patel, R. D., & Desai, S. (2021). Prevalence, Risk Factors, and Prescribing Trends in Chronic Renal Failure in the Indian Population. Journal of Pharmacology and Pharmacotherapeutics, 12(2), 86–90. https://doi.org/10.4103/jpp.JPP_149_20