Volume 16, Issue 3

2025 · pp. 249–348 · 10 articles

Volume: 16
Issue: 3
Published: 2025
Pages: 249–348
Articles: 10
Sections: 4
ISSN: ISSN: Print - 0976-500X, Online - 0976-5018
Journal: J Pharmacol. Pharmacother.

Review Article Original Research Article Short Communication Case Report

In this issue

Review Article

Review
Advanced Diagnostic and Therapeutic Approaches for Effective Management of Bladder Malignancies
Badriyah Shadid Alotaibi, Nihal Abdalla Ibrahim, Saira Azhar, Aamna Shah, Hamdah Omar, Munaza Ijaz
pp. 249–263 · DOI: 10.1177/0976500X241303616 · Published 2025
Background: Effectual management of Bladder Malignancies (BMs) is currently a global challenge due to their expensive therapeutic and diagnostic cost burden, together with augmented progression/recurrence rate. Objective…
Review
From Diversity to Standardization: Unveiling Key Parameters in Chick Ileum Bioassays for Enhanced Pharmacology Education and Research
Shruti Singh, Rajesh Kumar, Sunil Kumar Singh, Vikas Maharshi
pp. 264–273 · DOI: 10.1177/0976500X241312723 · Published 2025
Background: As traditional laboratory animal use faces ethical and logistical constraints, the chick ileum has been experimented with as an alternate tissue for bioassays, which is crucial for drug discovery and pharmaco…

Original Research Article

Article
The Quality Evaluation of Antibiotics for the Treatment of Diabetic Foot Ulcers in the Intensive Care Unit of Public Private Hospital, Semarang City
Gilang Rizki Al Farizi, A.A.P. Paramitha Vidiani, Fransisca Gloria, Dewi Karlina, Enggar Budi Astuti
pp. 274–282 · DOI: 10.1177/0976500X241306180 · Published 2025
Background: Diabetic ulcers are infections caused by the loss of the deepest skin tissue on the feet of patients with diabetes mellitus. Appropriate treatment, such as antibiotic therapy, is necessary to prevent the spre…
Article
Pharmacological Activities of Polyherbal Formulations of Saraca asoca and its Substitute Plants: A Comparative Evaluation Study
Thelakkadan Abidfaheem, Jibin Joy, Abdul Rasheed Abdul Rahaman, Kannappan Nagappan, Sathiavakoo Vigil Anbiah, Smitha Rani, Pattilthodika Suhail
pp. 283–290 · DOI: 10.1177/0976500X241309438 · Published 2025
Background: Saraca asoca (Roxb.) de Wild has been utilized in various commercial polyherbal preparations to treat gynecological disorders. Adulteration or replacement of similar raw pharmaceuticals is a widespread techni…
Article
Benzoxazinone Derivatives as Antiplatelet: Synthesis, Molecular Docking, and Bleeding Time Evaluation
Kholis Amalia Nofianti, Juni Ekowati, Nuzul Wahyuning Diyah, Luqmanul Hakim
pp. 291–301 · DOI: 10.1177/0976500X241305440 · Published 2025
Background: The recurrence of atherosclerosis is still a global problem. Unfortunately, the drugs currently being used are reported to have resistance. Objectives: To prevent the recurrence of atherosclerosis disease, th…
Article
Development and Validation of a Robust LC-MS/MS Method for Quantitation of a Novel Kinase Inhibitor, Ritlecitinib, in Rat Plasma: Application in Pharmacokinetic Study
Katari Pavan Kumar, Areti Anka Rao
pp. 302–310 · DOI: 10.1177/0976500X241289642 · Published 2025
Background: Ritlecitinib (RIT) is a novel kinase inhibitor with promising therapeutic applications in the treatment of auto-immune disease alopecia areata. Accurate quantification of RIT in biological matrices is essenti…
Article
DNA Damage Underlies the Cytotoxic and Apoptotic Effects of Selected Ethiopian Medicinal Plants against Cancer Cell Lines
Adamu T. Bekele, Sheila Almaraz Postigo, Kaleab Asres, Ephrem Engidawork, Atanasio Pandiella
pp. 311–323 · DOI: 10.1177/0976500X241312720 · Published 2025
Background: Plants are attractive sources of anti-cancer agents. However, there is limited data about the anti-cancer potential of Ethiopian medicinal plants traditionally used for the treatment of cancer. Objectives: To…
Article
Synergistic Effects of Cordyceps militaris and Alpha-lipoic Acid on Brain Disorders Associated with Age-dependent Oxidative Stress
Harish Kumar, Seema Bansal, Rishabh Chaudhary, Wandeep Dagar, Neha Goyal, Khushboo Aggarwal, Sumeet Gupta, Sunayna Choudhary
pp. 324–336 · DOI: 10.1177/0976500X241303566 · Published 2025
Background: Oxidative stress is the primary factor responsible for the development of neuroinflammation and brain deficits. As aging occurs, the chances of oxidative stress increase due to lifestyle modification, environ…

Short Communication

Communication
Treatment of Insomnia by Zopiclone in Older Adults Hospitalized in a Geriatric Hospital: A Retrospective Study
Helena Lebreton, Nadia Ladjouzi, Hendriniaina Raveloson, Diana Lopez-Leret, Joël Schlatter
pp. 337–341 · DOI: 10.1177/0976500X251314602 · Published 2025
Background: Insomnia is a significant public health problem that can affect up to 50% of older adults. Pharmacological treatments are commonly used such as benzodiazepines (BZD) and related Z-drug zopiclone. Objectives: …

Case Report

Article
Ayurvedic Management of Sciatica with Medicated Enema and Bloodletting: A Case Report
Pooja Basnal, Preeti Borkar, Sonia Manda, Pratyendra Pal
pp. 342–348 · DOI: 10.1177/0976500X241309446 · Published 2025
Background: The most common condition that restricts movement is low back pain, which is particularly common in the most productive years of life. Sciatica syndrome accounts for 40% of patients’ severe lower back pain. P…