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    Journal of Pharmacology and Pharmacotherapeutics volume 16, issue 4 cover
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    Cover: Journal of Pharmacology and Pharmacotherapeutics

    Journal of Pharmacology and Pharmacotherapeutics

    Volume 16, Issue 4

    2025 · pp. 353–447 · 11 articles

    Volume
    16
    Issue
    4
    Published
    2025
    Pages
    353–447
    Articles
    11
    Sections
    4
    ISSN
    ISSN: Print - 0976-500X, Online - 0976-5018
    Journal
    J Pharmacol. Pharmacother.

    In this issue

    Guest Editorial

    1. Article

      Hypothesis to Citation: Exploring the Intersections of Research Methodology, Indexed Publications, and Scientific Ethics

      Pitchai Balakumar, Hema Subramonian, Murugan Thangiah, Saravanan Pandiaraj, Shubhada Nagarkar, P.K. Srividhya, Arasu Chellaiah, Gowraganahalli Jagadeesh

      pp. 353–361 · DOI: 10.1177/0976500X251363677 · Published 2025

      The increasing pressure on academic faculty to balance teaching, research productivity, publication impact, and ethical integrity amidst stringent institutional and global academic expectations poses significant challeng…

    Review Article

    1. Review

      Exploring Interleukin-6 Inhibitor Antibodies in Combatting SARS-CoV-2 and its Mutated Variants: Challenges and Future Directions

      Mohammed Ali Bakkari, Gassem Ghoal, Fahad Y. Sabei, Awaji Y. Safhi, Sivakumar S. Moni

      pp. 362–374 · DOI: 10.1177/0976500X251316939 · Published 2025

      The aim of this study is to investigate the efficacy of interleukin-6 (IL-6) inhibitor antibodies as a therapeutic agent to combat severe COVID-19. Given the constant evolution of severe acute respiratory syndrome corona…

    Original Research Article

    1. Article

      Assessing the Anticancer Potential of Compounds from Caesalpinia sappan Wood against Mutant EGFR in Lung Squamous Cell Carcinoma: Computational Insights

      Shaik Pashmina, Nitya Krishnasamy, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

      pp. 375–385 · DOI: 10.1177/0976500X241305443 · Published 2025

      Background: Lung squamous cell carcinoma (LUSC), a subtype of non-small cell lung cancer (NSCLC), frequently harbors mutations in the epidermal growth factor receptor (EGFR), which regulates cell proliferation and surviv…

    2. Article

      A Novel Non-invasive Approach, “DrOroscope,” for Early Detection of Dysplasia in Oral Mucosal Lesions: A Cross-sectional Study

      Mounika Yeladandi, T. N. Uma Maheswari, Swetha Bindu Padala, Mekala Mary Sujatha, Harika Vemula, Tejaswi Kala, Mohammed Abidullah

      pp. 386–394 · DOI: 10.1177/0976500X241300758 · Published 2025

      Background: Oral cancer is a significant global burden in the present scenario, and early detection has critical importance in improving the survival rate. Devices which aid in the early diagnosis of dysplastic lesions n…

    3. Article

      Hypolipidemic and Hepatoprotective Effect of Linum usitatissimum and Moringa oleifera Seeds in Diabetic Induced Damage in Rats

      Nitu Sahoo, Dillip Kumar Bishi, Vartika Srivastava, Chaitali Pattanayak, Sougata Sarkar

      pp. 395–401 · DOI: 10.1177/0976500X241303668 · Published 2025

      Background: Diabetes mellitus is a chronic metabolic disorder and a fast-growing global problem. Studies have shown that Linum usitatissimum has anti-inflammatory and antioxidant properties that decrease blood sugar and …

    4. Article

      Pharmaceutical Frontliners: Community Pharmacists’ Contribution to Managing Medication Needs During a Health Crisis— The COVID-19 Era as an Example

      Noor R. Al-Hasani, Fadya Y. Al-Hamadani, Dhulfiqar N. Alhilali, Ali Azeez Al-Jumaili, Faaiz Y. Alhamdani

      pp. 402–411 · DOI: 10.1177/0976500X251356772 · Published 2025

      Background: Community pharmacists faced more complex challenges in meeting patients’ medication needs during the pandemic than previously reported in the literature. Objectives: To explore the perception and abilities of…

    5. Article

      Pharmacognostic Evaluation of Parmelia sulcata Taylor and its Cytotoxic Effects on a Glioblastoma Cell Line

      Vikrant Arya, Ranjeet Kaur Parmar, Amandeep Kaur Gill, Ashutosh Acharya, Yatendra Singh, Anupam Jamwal

      pp. 412–421 · DOI: 10.1177/0976500X241303567 · Published 2025

      Objectives: The current study aims to establish the pharmacognostic profile and evaluate the cytotoxic potential of Parmelia sulcata Talyor in the glioblastoma cell line. Materials and Methods: In this experimental inves…

    6. Article

      Unlocking Nutraceutical Potential: Metabolomic Analysis Reveals Therapeutic Compounds in Rice

      Konganam Veedu Faseela, Pathrose Berin, Appukuttan Jayadeep, Sidharthan Biju, Joseph Jiji, P. S. Abida, Mathew Deepu

      pp. 422–432 · DOI: 10.1177/0976500X241309437 · Published 2025

      Background: Rice varieties enriched with potential bioactive compounds are poised to make a significant contribution to global health. It is anticipated that edible medications made from rice seeds will lead to novel the…

    7. Article

      Low Back Pain Management through Bowel Lavage (Panchaprasrutik Basti)—A Single Arm Clinical Trial

      Bhashanjali Singh, Mamata Nakade, Sidhi Sharma

      pp. 433–438 · DOI: 10.1177/0976500X251313603 · Published 2025

      Background: Low back pain is a pervasive and often debilitating musculoskeletal condition that affects millions of people worldwide. Low back pain affects 619 million globally (10%) and may rise to 843 million by 2050. I…

    8. Article

      Effect of Herbal Antioxidant on Push-out Bond Strength of Resin-based Composite to Dentin after Intracoronal Bleaching: An in vitro Study

      Parinitha MS, Akshay G, Vidya G. Doddawad, Ashwini Tumkur Shivakumar, Sowmya Halasabalu Kalgeri

      pp. 439–445 · DOI: 10.1177/0976500X241304562 · Published 2025

      Background: Bleaching can enhance the appearance of stained teeth while maintaining their structural integrity. The antioxidant properties of green tea and pine bark extracts related to the effect on dental hard tissues …

    Obituary

    1. Article

      Obituary

      pp. 446–447 · DOI: 10.1177/0976500X251363676 · Published 2025