Volume 4, Issue 3

Baldness, a new marker for coronary heart disease risk

Sivagnanam G

pp. 223–224 · DOI: · Published 2013

A meta‑analysis of observational studies comprising a total of 36,690 participants showed that vertex baldness is associated with an increased risk of CHD with the relationship depending on the severity of baldness while…

Majority general practitioners prescribe “Impure Placebo” drugs

pp. 223–223 · DOI: · Published 2013

“Pure placebos are interventions like sugar pills, which are available commercially or saline injections without direct pharmacologically active ingredients for the condition being treated.

A new drug belonging to a novel class of drugs for type 2 diabetes

Sivagnanam G

pp. 224–224 · DOI: 10.4103/0976-500X.114621 · Published 2013

The FDA approval of canagliflozin (Invokana) was based on data involving over 10,285 type 2 diabetes patients, which showed improvement in hemoglobin A1c and fasting plasma glucose levels. Canagliflozin has been tested a…

Improving quality of medical education in India: The need to value and recognize academic scholarship

Thomas V. Chacko

pp. 171–173 · DOI: 10.4103/0976-500X.114595 · Published 2013

We are all currently in the midst of a high tide of concern and clamor for taking urgent action to improve the standards of the medical education in the country. In this context, there have been some refreshing initiativ…

The metabolic syndrome and schizophrenia: A comorbidity or an association?

pp. 174–175 · DOI: · Published 2013

Individuals with schizophrenia have 2-3 times higher rates of mortality than the general population. Causes of excessive mortality are increased suicide rates and mortality of natural causes such as cardiovascular events…

Metabolic syndrome in schizophrenia: Differences between antipsychotic‑naïve and treated patients

Rakesh K. Chadda, Prashanth Ramshankar, Koushik S. Deb, Mamta Sood

pp. 176–176 · DOI: 10.4103/0976-500X.114596 · Published 2013

Metabolic syndrome (MetS) has been recognized as a risk factor for cardiovascular morbidity and mortality in general population and in patients with severe mental illnesses like schizophrenia. This paper reviews studies …

N-acetyl cysteine in clomiphene citrate resistant polycystic ovary syndrome: A review of reported outcomes

Lekha Saha, Sharonjeet Kaur, Pradip Kumar Saha

pp. 187–188 · DOI: 10.4103/0976-500X.114597 · Published 2013

Clomiphene citrate (CC) has been the gold‑standard drug for ovulation induction in polycystic ovary syndrome (PCOS), but still CC resistance is seen in approximately 15-40% in women with PCOS. N‑acetyl cysteine (NAC), a …

Neuroprotective role of naringenin on carbaryl induced neurotoxicity in mouse neuroblastoma cells

Vijaya Prakash Krishnan Muthaiah, Lavanya Venkitasamy, Felicia Mary Michael, Kirubhanand Kirubhanand

pp. 192–197 · DOI: 10.4103/0976-500X.114599 · Published 2013

Objective: Neuroprotective effect of naringenin against carbaryl toxicity was studied in mouse neuroblastoma cell line. Materials and Methods: Mouse neuroblastoma cells (Neuro 2A) obtained from National Center for Cell S…

Effects of structural analogues of apelin‑12 in acute myocardial infarction in rats

Oleg I. Pisarenko, Larisa I. Serebryakova, Irina M. Studneva, Yulia A. Pelogeykina, Olga V. Tskitishvili, Zhanna D. Bespalova, Maria V. Sidorova, Andrei A. Az’muko, Denis N. Khatri, Maria E. Pal’keeva

pp. 198–203 · DOI: 10.4103/0976-500X.114600 · Published 2013

Objective: To examine cardioprotective effects of С‑terminal fragment of adipokine apelin‑12 (A12), its novel structural analogue [MeArg1, NLe10]‑A12 (I), and [d‑Ala12]‑A12 (II), a putative antagonist of APJ receptor, em…

Audit of use of antibiotics and zinc supplement in childhood diarrhea

Kalahasthi Priyadarshini, Vishnu Raj, Sadasivam Balakrishnan

pp. 204–205 · DOI: 10.4103/0976-500X.114601 · Published 2013

Diarrhea refers to the passage of loose or watery stools, and occurs at some point in the life of nearly every child. It continues to be a global problem in children, which accounts for 18% of child deaths and 13% of all…

Modulation of inflammatory pain in response to a CCR2/CCR5 antagonist in rodent model

Masayuki Okamoto, Takeshi Suzuki, Nobuhide Watanabe

pp. 208–210 · DOI: 10.4103/0976-500X.114605 · Published 2013

C‑C chemokine ligand 2 (CCL2), previously referred to as monocyte chemoattractant protein‑1 (MCP‑1), a 78 amino acid secreted protein, belongs to the CC subfamily and controls the recruitment of monocytes, memory T‑cells…

An experimental spinal cord injury rat model using customized impact device: A cost-effective approach

Vijayaprakash K.M, Sridharan N.

pp. 211–213 · DOI: 10.4103/0976-500X.114607 · Published 2013

Till date, NYU MASCIS (New York University, Multicenter Animal Spinal Cord Injury Study) impactor and Ohio State University electromagnetic spinal cord injury device impactor were under use for simulating an experimental…

Pseudocyesis: A complication of antipsychotic-induced increased prolactin levels and weight gain

Sandeep Grover, Akhilesh Sharma, Deepak Ghormode, Nikita Rajpal

pp. 214–216 · DOI: 10.4103/0976-500X.114610 · Published 2013

Pseudocyesis or phantom pregnancy is characterized by a false belief in a non-pregnant female that she is pregnant and this belief is usually associated with bodily signs of pregnancy. In some of the patients, this belie…

Good! Is it the best???

Sandhiya Selvarajan, Steven Aibor Dkhar, Ajith Ananthakrishna Pillai

pp. 220–221 · DOI: 10.4103/0976-500X.114611 · Published 2013

The published article comparing ranolazine 500 mg BD and ivabradine 5 mg BD over 8 weeks has shown a reduction in the number of angina attacks per week from baseline angina frequency of 1.8 ± 0.2/week to complete absence…

Reply to “Good! is it the best ???

Aditi Chaturvedi, Yogendra Singh, Harish Chaturvedi, Vijay Thawani, Sakshi, Deepak Parihar

pp. 221–222 · DOI: 10.4103/0976-500X.114622 · Published 2013

The questions that were put forth to the patients were similar to those that were followed in the ERICA trial, i.e., patients were evaluated for average frequency of self‑reported anginal episodes during the treatment ph…