Volume 19, Issue 37

Review Article

1. Review

   Natural Bioactives Targeting the GLP-1 Pathway: A Promising Approach for Diabetes Management

   Rohini Chandrakant Kolhe, Priyanka Sudhakar Chaudhari, Manisha Pradeep Khaire, Priyanka Kantaram Ghadage, Archana Sopan More

   pp. 1–14 · DOI: 10.5530/phrev.20252106 · Published

   Diabetes, a disorder that is becoming more and more common in the world; however, it affects over 400 million people worldwide. Despite considerable growth in diabetes management, most patients often suffer from a signif…

2. Review

   Silymarin: A Historical and Scientific Exploration of its Medicinal Properties

   Hebbani Nagarajappa Shivaprasad, Vinaya Gharabude, Sravani Thimmannagari, Madhu Krishnamani, Gaurav Soni

   pp. 102–108 · DOI: 10.5530/phrev.20250002 · Published

   Silybum marianum, or milk thistle, has been used medicinally for over 2,000 years, mainly to treat liver conditions. Silymarin, a complex mixture of flavonolignans, is present in the plant, which contributes to its pharm…

3. Review

   The Significance of Bioactive Compounds in The Complex Realm of Cardiovascular Complications

   Sreejita Chakraborty, Adib Hussain, Arabinda Nayak

   pp. 109–118 · DOI: 10.5530/phrev.20252203 · Published

   Leading cause of morbidity and death globally, Cardiovascular Diseases (CVDs) call for sensible preventive and treatment plans. Recent studies have concentrated on bioactive chemicals originating from natural dietary sou…

4. Review

   The Case for Cannabidiol-Integration of Eastern and Western Medical Traditions and the Promise for the Future: A Narrative Review and Commentary

   Peter Pressman, Julia Hoeng, Pornchai Padmindra, Sakan Warinhomhoun, Wallace Hayes

   pp. 119–126 · DOI: peter.pressman@maine.edu · Published

   Our intent in the following narrative review and commentary is to underscore the importance of critically re-exploring ancient and enduring medical traditions. We support a view that rediscovering and augmenting the elem…

5. Review

   Unraveling Advanced Glycation End Products: Mechanisms, Pathophysiology, and Emerging Natural Therapeutic Interventions

   Dipeksha Macwan, Hiteshkumar V. Patel

   pp. 15–22 · DOI: 10.5530/phrev.20252119 · Published

   Protein glycation is an emerging issue that needs attention because it presents a hazard to the health of individuals. Through a sequential succession of non-enzymatic biochemical reactions occurs during glycation of pro…

6. Review

   Ecological and Medicinal Importance of Ficus microcarpa: Unveiling the Diversity of a Versatile Plantq

   Disha Arora, Shweta Agarwal

   pp. 23–29 · DOI: 10.5530/phrev.20252127 · Published

   The genus Ficus, belonging to the Moraceae family, encompasses a diverse group of trees, shrubs and vines, including notable species such as Ficus microcarpa, F. carica (common fig) and F. lyrata (fiddle-leaf fig). Known…

7. Review

   Ayurvedic Concept of Garbhini Paricharya: A Critical Review

   Renuka Nayak, Neeraj Agrawal, Lowkesh Chandravanshi, Satyawati Rathia, Pallavi Kurre

   pp. 30–38 · DOI: 10.5530/phrev.20252167 · Published

   Pregnancy is a very crucial phase in a women’s life. Proper care during this phase is important. It includes systematic diet plan, regular check-ups, healthy regimen, and mindful activities of the pregnant women. In Ayur…

8. Review

   Exploring the Potential of Traditional Medicinal Plants for Central Nervous System Related Activity

   Sougata Santra, Adib Hussain, Arabinda Nayak

   pp. 39–47 · DOI: 10.5530/phrev.20252202 · Published

   People have used native healing plants in different old-school medicine practices worldwide for hundreds of years to fix all sorts of health problems, including ones that mess with the brain and nerves. As science gets b…

9. Review

   AI-Guided Phytochemical and Drug Synergy Mapping of Peganum harmala and Nigella sativa in Cancer Therapy

   Abdullah Faisal Albukhari

   pp. 48–60 · DOI: 10.5530/phrev.20252224 · Published

   Background:Cancer continues to pose a significant health challenge worldwide, characterized by increasing incidence rates and constraints in current treatment options. These limitations arise from issues such as multidru…

10. Review

    Local Aphrodisiac Plants Available in Sikkim Himalaya for Male Infertility (Traditional Aspects, in vivo and in vitro Evidences): A Review Insight

    Sagarika Khatiwara, Tiewlasubon Uriah Khar, Sonam Bhutia

    pp. 61–69 · DOI: 10.5530/phrev.20252270 · Published

    Objectives: This review aims to know the status and gaps in male infertility and enhancement measures in term of traditional utility, In vitro & in vivo studies. Methodology: The data were collected through an extensive …

11. Review

    Nutraceutical Value of Narikela Khanda and its Importance for Children’s Growth and Nutrition: A Review Article

    Akanksha Mishra, Lowkesh Chandravanshi

    pp. 70–74 · DOI: 10.5530/phrev.20250001 · Published

    Every age group needs proper nutrition. The three foundations of Ayurveda-Diet (Ahara), Sleep (Nidra) and Celibacy (Brahmcharya)-are referred to as Trayopstambh in Ayurveda. The three pillars support the body.[1] Among t…

12. Review

    A Comprehensive Study on the Cytotoxic Action of Bioactive Compounds of Three Himalayan Herbs

    Gaurav Upadhyay, Rajesh Kumar Sharma

    pp. 75–82 · DOI: 10.5530/phrev.20252294 · Published

    Globally, Hepatocellular Carcinoma (HCC) is one of the main causes of cancer-related mortality generally affecting men more than women, and with an age of onset between late teens and 30s. Lamiaceae family also known as …

13. Review

    Biochemistry of Traditional Herbal Compounds and their Molecular Targets

    Anih David Chinonso, Arowora Adebisi Kayode, Moses Abah Adondua, Ugwuoke Kenneth Chinekwu

    pp. 83–90 · DOI: anih.david@fuwukari.edu.ng · Published

    Traditional herbal medicine represents a rich and diverse pharmacological reservoir that has long been utilized for treating various ailments across cultures. The growing interest in evidence-based phytotherapy has promp…

14. Review

    AI-Guided Synergistic Anticancer Potential of Peganum hamala and Black Garlic (Allium nigrum): A Systematic Review of Mechanistic Insights and Preclinical Evidence

    Abdullah Faisal Albukhari

    pp. 91–101 · DOI: 10.5530/phrev.20252310 · Published

    Peganum harmala and black garlic (Allium nigrum) are traditional medicinal plants recognized for their unique anticancer effects. Recent studies indicate that their phytochemical components may work together synergistica…