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    Pharmacognosy MagazineNOW IN
    Article

    Antioxidant and anti-inflammatory activities of Cissus arnottiana B. Heyne ex Planch

    Hui Yang1, Shanshan Yuan2, Yongsheng Li3★★ Corresponding author

    1. 1Department of Gastroenterology, The Second Affiliated Hospital of Xi’an Jiaotong University (Xibei Hospital), China.
    2. 2Departement of Gastroenterology, The Affiliated Xi’an Central Hospital of Xi’an Jiaotong University, China.
    3. 3Department of Pharmacy, Honghui Hospital, Xi’an Jiaotong University, Xi’an, China.

    CORRESPONDENCE

    Yongsheng Li

    Department of Pharmacy, Honghui Hospital, Xi’an Jiaotong University, Xi’an, China.

    superlys2018@sina.com

    Received: 21-04-2021; Revised: 31-07-2021; Accepted: 09-09-2021.

    Volume 17, Issue 76 · pp. 700–707 · PUBLISHED 24 January 2022 · DOI: 10.4103/pm.pm_177_21

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant, but other species are less explored. Objective: To evaluate the antioxidant and anti-inflammatory activities of <em>Cissus arnottiana</em> B. Heyne ex Planch. Materials and Methods: The methanolic extract of <em>C. arnottiana</em> leaves was evaluated for antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide, and hydroxyl radical scavenging assays. Anti-inflammatory activity was assessed using the protein denaturation inhibition assay and the carrageenan-induced rat paw edema model. Results: The extract showed significant antioxidant activity in a concentration-dependent manner. In the anti-inflammatory assay, the extract exhibited significant inhibition of protein denaturation and reduced paw edema in rats compared to the standard drug, diclofenac sodium. Conclusion: <em>C. arnottiana</em> possesses significant antioxidant and anti-inflammatory activities, supporting its traditional use.

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      Yang, H., Yuan, S., & Li, Y. (2022). Antioxidant and anti-inflammatory activities of Cissus arnottiana B. Heyne ex Planch. Pharmacognosy Magazine, 17(76), 700–707. https://doi.org/10.4103/pm.pm_177_21