Volume 17, Issue 76

24 January 2022 · pp. 657–885 · 29 articles

Volume: 17
Issue: 76
Published: 24 January 2022
Pages: 657–885
Articles: 29
Sections: 1
ISSN: ISSN: Print - 0973-1296, Online - 0976-4062
Journal: Pharmacogn. Mag.

Original Article

In this issue

Original Article

Article
Comprehensive Analysis of Agronomic Characters, Chemical Compounds, and Antioxidant Activity in Chaenomeles Fruits at Different Developmental Stages
Qingying Fang, Minzhen Yin, Shanshan Chu, Xiangwei Chang, Mei Yang, Huasheng Peng
pp. 657–665 · DOI: 10.4103/pm.pm_111_21 · Published 24 January 2022
Objectives: This study aimed to determine the appropriate harvest time for different uses of Chaenomeles fruits. Materials and Methods: Agronomic characteristics, chemicals, and antioxidant activity of fruits were detect…
Article
Phytochemical Investigation of Bauhinia winitii Based on Alpha‑Glucosidase Inhibitory Effect and Molecular Docking Affirmation
Sukanya Dej‑adisai, Ichwan Ridwan Rais, Chatchai Wattanapiromsakul, Thanet Pitakbut
pp. 666–672 · DOI: 10.4103/pm.pm_204_21 · Published 24 January 2022
Objectives: The aim of this study was to investigate the phytochemical constituents and anti‑alpha glucosidase activity of BW. Materials and Methods: Phytochemical study was based on the alpha‑glucosidase inhibitory effe…
Article
Effects of Retinoic Acid‑Induced Osteoporosis on Pharmacokinetics and Tissue Distribution of 2,3,5,4’‑Tetrahydroxy Stilbene‑2‑Ο‑β‑D‑Glucoside and β‑Ecdysterone in Rats
Sun Yan‑Tao, Wang Bing, Kang Ting‑Guo
pp. 673–678 · DOI: 10.4103/pm.pm_51_21 · Published 24 January 2022
Background: The compatibility of Radix Polygoni multiflori-Achyranthes (RPMA) root is a Traditional Chinese medicine pair frequently used in the clinic and has good anti‑osteoporosis (OP) effects. Materials and Methods: …
Article
Antifibrotic Effects of Lilii Bulbus Extract in a Mouse Model of Bleomycin‑induced Pulmonary Fibrosis
Shuen‑Cheng Chiang, Jihye Park, Jinhyun Bae, Hyejin Joo, Donghyun Lee, Kwan‑Il Kim, Seok‑Jae Ko, Jae‑Woo Park, Youngmin Bu, Beom‑Joon Lee
pp. 679–683 · DOI: 10.4103/pm.pm_117_21 · Published 24 January 2022
Objectives: Lilii Bulbus (LB), a lung‑moistening herbal medicine, has been used to treat the symptoms of pulmonary fibrosis, including dry cough and dyspnea. In this study, we investigated whether LB water extract (LIB) …
Article
Data Mining and Network Pharmacology Study on Dried Tangerine Peel and Immature Tangerine Peel Essential Oil as a Treatment for Liver Depression and Insomnia
Gang Ke, Guilin Ren, Qingrong Pu, Rui Huang, Ting Liu, Lu Liu, Qian Gong, Jie Li, Rong Li
pp. 684–694 · DOI: 10.4103/pm.pm_559_20 · Published 24 January 2022
Objectives: To study the mechanism of volatile oil in treating liver depression and insomnia. Materials and Methods: Through data mining, we found dried and immature tangerine peel as a prescription for treating liver de…
Article
Arbortristoside‑A: A Promising Bioactive Moiety from Nyctanthes arbortristis Linn. against Hemorrhoid
Sanjita Das, Saumya Das, Aniruddh Pratap Singh, Manas Kumar Das, Nishu Gautam, P. Ayash Kumar, Sradhanjali Mohapatra, Richa Shakya
pp. 695–699 · DOI: 10.4103/pm.pm_573_20 · Published 24 January 2022
Background: Hemorrhoid disease is becoming a common problem in modernized society and its treatment is less developed. Although there are many plants used traditionally, proper scientific evidence is still lacking. Nycta…
Article
Antioxidant and anti-inflammatory activities of Cissus arnottiana B. Heyne ex Planch
Hui Yang, Shanshan Yuan, Yongsheng Li
pp. 700–707 · DOI: 10.4103/pm.pm_177_21 · Published 24 January 2022
Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant, but other species are less explored. Objective: To evaluate the anti…
Article
Systems Bioinformatic Approach to Determine the Pharmacological Mechanisms of Radix Astragali and Radix Angelicae sinensis in Idiopathic Pulmonary Fibrosis
Yufeng Zhang, Lina Gu, Juan PuYang, Mengying Liu, Qingqing Xia, Weilong Jiang, Mengshu Cao
pp. 708–718 · DOI: 10.4103/pm.pm_9_21 · Published 24 January 2022
Objectives: The objective of the study was to regulate the pharmacological mechanism of RA and RAS in IPF treatment. Materials and Methods: Microarray datasets for IPF were examined in the Gene Expression Omnibus databas…
Article
Gas Chromatography Coupled With Mass Analysis Phytochemical Profiling, Antiproliferative and Antimigratory Effect of Tagetes lucida Leaves Extracts on Cervical Cancer Cell Lines
Onelio Mora-Candelario, Marco Antonio Leyva-Vázquez, Miguel Angel Mendoza-Catalán, Laura Álvarez, Mayra Antunez-Mojica, Julio Ortiz-Ortiz, Macdiel Acevedo-Quiroz
pp. 719–727 · DOI: 10.4103/pm.pm_49_21 · Published 24 January 2022
Objectives: The aim of this study was to identify, in Tagetes lucida organic leaf extracts, the bioactive compounds with antiproliferative and antimigratory activities on the human cervical cancer (CCa) cell lines human …
Article
Processed Rehmanniae radix can Improve Cold Syndrome Damage of Rats by Regulating Glycolipid Metabolism
Mengmeng Wang, Yingying Ke, Yangyang Wang, Tong Liu, Yage Li, Zengfu Shan, Wangyang Mi, Ning Zhou, Weisheng Weisheng
pp. 728–734 · DOI: 10.4103/pm.pm_282_20 · Published 24 January 2022
Objectives: The present study intended to assess the drug property of Rehmanniae Radix Praeparata (PRR), called Shudihuang in traditional Chinese medicine and to discover its mechanism of cold syndrome in rats. Materials…
Article
Beneficial Effect of Moringa stenopetala (Bak.f) Cuf. on Lithium–Pilocarpine‑Induced Temporal Lobe Epilepsy in Experimental Animals
Etsay Weldekidan Tsegay, Rajkapoor Balasubramanian, Kald Beshir Tuem, Abadi Kahsu Gebre
pp. 735–742 · DOI: 10.4103/pm.pm_276_20 · Published 24 January 2022
Background: Moringa stenopetala is traditionally used for the treatment of epilepsy in southern Ethiopia. Additionally, the plant material is used for the treatment of various ailments such as pain, diabetes, hypertensio…
Article
Optimization of Steaming Process for Polysaccharides from Panax notoginseng by Box‑Behnken Response Surface Methodology and Comparison of Immunomodulatory Effects of Raw and Steamed Panax notoginseng Polysaccharides
Na Xing, Zhihong Zhang, Donghui Peng, Yuxin Li, Xue Wang, Rui Wang, Yanshan He, Yuanning Zeng, Haixue Kuang, Qiuhong Wang
pp. 743–751 · DOI: 10.4103/pm.pm_42_21 · Published 24 January 2022
Aim: We aimed to optimize the steaming process of Pana notoginseng using response surface methodology (RSM). Materials and Methods: The yield and immune activity of steamed P. notoginseng polysaccharides (s‑PNPs) was use…
Article
Antischistosomal Evaluation of Stem Bark’s Extract and Chemical Constituents from Anonidium mannii against Schistosoma mansoni
Josette Linda Toussi Matchi, Diderot Tchamo Noungoue, Guilhem Chaubet, Jérôme Boissier, Isabelle Kuhn, Jean Claude Tchouankeu, Marc Nothisen, Sylvain Ursuegui, Silvère Augustin Ngouela, Alain Wagner
pp. 752–758 · DOI: 10.4103/pm.pm_29_21 · Published 24 January 2022
Aim: The goal of this study was to evaluate the anti‑Schistosoma mansoni activity of fractions and constituents from A. mannii’s stem bark and also to search efficient inhibitors of a recently discovered ectoenzyme of S.…
Article
Species Difference of Asarinin Metabolism in vitro and its Effect on the Activity of Cytochrome P450 Enzymes
Hu Tingting, Shi Xianbao, Jiayin Hu, Yang Jingming
pp. 759–764 · DOI: 10.4103/pm.pm_200_21 · Published 24 January 2022
Aim: To investigate the metabolic behaviors of asarinin in different species and found animal models with metabolic pathways similar to those in humans and to study the effect (inhibition or induction) between asarinin a…
Article
Effects of Cyclocarya paliurus Flavonoid Extract in Non-alcoholic Steatohepatitis Mice: Intermeshing Network Pharmacology and in vivo Pharmacological Evaluation
Senling Feng, Jing Zhang, Baoying Liang, Hongliu Jin, Zhongwen Yuan
pp. 765–773 · DOI: 10.4103/pm.pm_21_21 · Published 24 January 2022
Objectives: Non-alcoholic steatohepatitis (NASH) is the second most common cause of the hepatitis. In this study, we aimed to investigate the effects and mechanisms of Cyclocarya paliurus (CPF) flavonoids extract in the …
Article
Effect of Aging and Geographical Variations in the Content of Guggulsterones and Metabolomic Profiling of Oleogum Resins of Commiphora wightii: The Indian Bdellium
Rajesh Kumar Verma, Mohammad Ibrahim, Avi Fursule, Ranjan Mitra, Jatavallabhula Lakshmi Narayana Sastry, Sayeed Ahmad
pp. 774–779 · DOI: 10.4103/pm.pm_76_21 · Published 24 January 2022
Objectives: In this paper, the impact of plant aging and geographical variations of guggulsterone (GS) content in oleo‑gum resin collected from different geographical regions of India has been examined. Materials and Met…
Article
Antidepressant Effect of Buddleja cordata Methanolic Extract in Chronic Stress Mouse Model
Griselda García-Alonso, Marco Atzori, Roberto Salgado, Adrian Báez, Marcela Miranda, Aylin Rangel, Edgar Guevara, Roberto Cuevas, José Manuel Vega-Riquer, José Guillermo Avila-Acevedo, Antonio Monroy-Noyola
pp. 780–785 · DOI: 10.4103/pm.pm_554_20 · Published 24 January 2022
Objectives: To explore the antidepressant effect of a methanolic extract of Buddleja cordata leaves (MEBc) in early maternal separation and chronic restraint stress mouse model. Materials and Methods: From day 2 to day 2…
Article
Astragaloside IV Inhibits Salmonella‑Induced Meningitis Via Modulation of Bacterial Virulence and Host Response
Zhonghua Chen
pp. 786–792 · DOI: 10.4103/pm.pm_55_21 · Published 24 January 2022
Objectives: To control Salmonella‑induced meningitis, in this study, we aimed to investigate the potential anti‑virulence activity and neuroprotective role of astragaloside IV (AS‑IV) under in vitro and ex vivo condition…
Article
Cytotoxic and Antitumor Properties of Ziziphus spina‑christi Found in Al Bahah Region of Hejaz Area: An In vitro Study on Oral Cancer Cell Lines
Abdulaziz Al Shahrani, Jagadish Virupaxi Hosmani, Ibrahim AlShahrani, Rafi Ahmad Togoo, Tasneem Sakinatul Ain, Sadatullah Syed, Master Luqman Mannakandath, Mohamed Khaled Abdulrahman Addas
pp. 793–801 · DOI: 10.4103/pm.pm_65_21 · Published 24 January 2022
Objectives: The probable cytotoxic effect of Z s‑c, found in Al Bahah region, on human oral cancer cell lines (SCC‑9) was assessed in the present study. Materials and Methods: Bioactive compounds of Z s‑c were evaluated …
Article
Chrysoeriol Promotes Functional Neurological Recovery in a Rat Model of Cerebral Ischemia
Guoqiang Shao, Shenxu Chen, Yijie Sun, Haizhu Xu, Fangfang Ge
pp. 802–810 · DOI: 10.4103/pm.pm_329_21 · Published 24 January 2022
Background: Stroke is among the leading causes of death worldwide, but current treatment options for cerebral ischemia are limited. Chrysoeriol is a natural isolated agent with bioactive pharmacological properties. Mater…
Article
Comparison of Esophageal Mucosa Protective Efficacy of Evodiae Fructus and Toosendan Fructus against Duodenogastroesophageal Reflux Esophagitis
Jin A. Lee, Mi‑Rae Shin, Hae‑Jin Park, Seong‑Soo Roh
pp. 811–818 · DOI: 10.4103/pm.pm_277_21 · Published 24 January 2022
Objectives: This work was aimed to assess the impact of Evodiae Fructus and Toosendan Fructus against esophageal mucosal injury with Duodenogastroesophageal Reflux Esophagitis (DGER). Materials and Methods: After inducin…
Article
Myricitrin Attenuates Hypoxic‑Ischemia‑Induced Brain Injury in Neonatal Rats by Mitigating Oxidative Stress and Nuclear Factor Erythroid 2‑Related Factor 2/Hemeoxygenase‑1/Antioxidant Response Element Signaling Pathway
Ting Yan, Man Lu
pp. 828–835 · DOI: 10.4103/pm.pm_397_20 · Published 24 January 2022
Objectives: In this study, we aimed to explore the neuroprotective efficacy of myricitrin and elucidate the mechanism of action of myricitrin through the regulation of nuclear factor erythroid 2‑related factor 2 (Nrf2)/h…
Article
Rhei Rhizoma and Citri Pericarpium Mixture Regulates Oxidative Stress and Tight Junction Proteins on Acute Reflux Esophagitis
Mi‑Rae Shin, Jin A Lee, Min Ju Kim, Hae‑Jin Park, Seong‑Soo Roh
pp. 836–843 · DOI: 10.4103/pm.pm_207_21 · Published 24 January 2022
The aim of the present study was to assess the impact of a Rhei Rhizoma and Citri Pericarpium (RC) mixture on esophageal mucosal injury in rats with acute reflux esophagitis (ARE). An experimental model of ARE was establ…
Article
Phytochemical Profiling and Antioxidant Potential of Cissus vitiginea and Cissus pallida
S. P. Dhanabal, K. P. Arun
pp. 844–851 · DOI: 10.4103/pm.pm_364_21 · Published 24 January 2022
Objectives: This study aimed to isolate a polysaccharide (PLY) from Cucurbita argyrosperma seeds and determine their antioxidant and antiglycation effects. Materials and Methods: The PLY fraction was isolated by hot wate…
Article
Gas Chromatography Coupled with Mass Spectrometry for the Rapid Characterization and Screening of Volatile Oil of Euphorbia fischeriana Steud
Qi Liu, Yu-Mei Wang, Wen-Hao Fu, Ai-Hua Zhang
pp. 852–856 · DOI: 10.4103/pm.pm_265_19 · Published 24 January 2022
Gas chromatography (GC)‑mass spectrometry is a powerful tool which is used in the analysis of volatile components in food and herbal medicine. Euphorbia fischeriana Steud., a traditional Chinese herb, has been used for t…
Article
Anti‑Fatigue Activities and Phytochemical Compositions of Turnip (Brassica rapa L.) Extracts
Yi Zhou, Zhanqiang Li
pp. 857–864 · DOI: 10.4103/pm.pm_470_20 · Published 24 January 2022
Objectives: The objective is to evaluate the anti‑fatigue properties and characterize the phytochemical compositions of turnip. Materials and Methods: Different proportions of turnip extract, including the total aqueous …
Article
Chemopreventive Strategies of Teucrium alopecurus de Noé Water Insoluble Fraction for Hepatocarcinogenesis in Lipopolysaccharide‑Induced Mice Models: Pharmacological Attributes
Fatma Guesmi, Manel Ben Ali, Ramla Ben Mouhoub, Amor Hedfi, Mohammad S. AL-Harbi, Ahmed Landoulsi
pp. 865–871 · DOI: 10.4103/pm.pm_585_20 · Published 24 January 2022
Objectives: The goal of this study is to investigate the inhibitory potential of TAlp in lipopolysaccharide (LPS)‑induced hepatic damage. Methods: Cell viability was measured by 3‑(4, 5‑dimethylthiazol‑2‑yl)‑2, 5‑dipheny…
Article
Quality Control of Bacopa monnieri by High‑Performance Liquid Chromatography Fingerprinting Combined with Chemometric Methods
Bhuban Mohan Padhiari, Asit Ray, Tarun Halder, Sudipta Jena, Bibhuti Bhusan Champati, Ambika Sahoo, Basudeba Kar, Biswajit Ghosh, Pratap Chandra Panda, Sanghamitra Nayak
pp. 872–881 · DOI: 10.4103/pm.pm_107_21 · Published 24 January 2022
Objectives: The present work was carried out to develop the chemical fingerprint and quality consistency of B. monnieri. Materials and Methods: Twenty‑four accessions of B. monnieri were collected from two provinces of E…
Article
In vivo Evaluation of Acalypha indica Extract Incorporated Electrospun Guar/PVA Nanofibrous Mats for Use as Active Wound Dressing Material
Preethi Jenifer, Mangathayaru Kalachaveedu, Ramajayan Pandian
pp. 882–885 · DOI: 10.4103/pm.pm_275_21 · Published 24 January 2022
Background: A. indica is a well‑known plant for its wound healing properties and has been used for decades by tribes of Asia and Africa. Materials and Methods: In vivo evaluation of fabricated electrospun nanofibrous mat…