Research Advancements in Pharmacological Activities and Mechanisms of Matrine
Xiaohui Chen1, Panpan Liu1, Yanni Mao1, Guiqin Wang1★★ Corresponding author
- 1Veterinary Pharmacology Lab, School of Agriculture, Ningxia University, Yinchuan, China.
CORRESPONDENCE
Guiqin Wang
Veterinary Pharmacology Lab, School of Agriculture, Ningxia University, Yinchuan, China.
Received: 17-04-2023; Accepted: 18-08-2023.
Volume 20, Issue 1 · pp. 189–205 · PUBLISHED 2024 · DOI: 10.1177/09731296231203458
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ABSTRACT
Matrine possesses a broad spectrum of pharmacological activities as one of the primary components of Chinese herbal medicine Sophora flavescens extract, along with fewer side effects and low toxicity. Matrine possesses anti-inflammatory, anti-cancer, anti-virus, antibiosis, and anti-oxidative properties and protects the central nervous and cardiovascular systems, immunosuppression, intestinal flora balance regulation, and broad-spectrum insecticidal activities. We reviewed the recent progress in matrine research in terms of the pharmacological activities and associated mechanisms to provide a reference for the wide and safe application of matrine.
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Chen, X., Liu, P., Mao, Y., & Wang, G. (2024). Research Advancements in Pharmacological Activities and Mechanisms of Matrine. Pharmacognosy Magazine, 20(1), 189–205. https://doi.org/10.1177/09731296231203458