Volume 11, Issue 44s1

ORIGINAL ARTICLE

1. Article

   In vitro α‑amylase and α‑glucosidase inhibitory effects and cytotoxic activity of Albizia antunesiana extracts

   Talent Chipiti, Mohammed Auwal Ibrahim, Moganavelli Singh, Md. Shahidul Islam

   pp. 231–236 · DOI: 10.4103/0973-1296.166018 · Published 24 September 2015

   Context: Diabetes mellitus is a chronic disease, and its incidence is tremendously increasing globally. Decreasing postprandial hyperglycemia by retarding glucose absorption through inhibiting carbohydrates digesting enz…

2. Article

   Poncirus trifoliata Rafin. induces the apoptosis of triple‑negative breast cancer cells via activation of the c‑Jun NH(2)‑terminal kinase and extracellular signal‑regulated kinase pathways

   Hye‑Yeon Han, Mi Heon Ryu, Yonghae Son, Guemsan Lee, Seung-Hwa Jeong, Hyungwoo Kim

   pp. 237–243 · DOI: 10.4103/0973-1296.166056 · Published 24 September 2015

   Background: Poncirus trifoliata Rafin. is a traditional medicine with known anti‑inflammatory and anti‑cancer properties. Traditionally, it is used to control chronic inflammation, allergy and gastrointestinal diseases s…

3. Article

   Evaluation of Antiplasmodial activity of extracts and constituents from Ampelozizyphus amazonicus

   Dominique F. M. do Carmo, Ana Claudia F. Amaral, Marta Machado, Dinora Lopes, Aurea Echevarria, Virgílio E. Rosário, Jefferson Rocha de A. Silva

   pp. 244–250 · DOI: 10.4103/0973-1296.166071 · Published 24 September 2015

   Background: Ampelozizyphus amazonicus Ducke, a plant that is widely used by the population of the Amazonian region to prevent and treat malaria, was investigated in this work, which describes, for the first time, the ant…

4. Article

   Antihyperglycemic effect of thymoquinone and oleuropein, on streptozotocin‑induced diabetes mellitus in experimental animals

   Sibghatullah Muhammad Ali Sangi, Mansour Ibrahim Sulaiman, Mohammed Fawzy Abd El‑wahab, Elsamoual Ibrahim Ahmedani, Soad Shaker Ali

   pp. 251–257 · DOI: 10.4103/0973-1296.166017 · Published 24 September 2015

   Background: Diabetes mellitus is one of the most important diseases related with endocrines. Its main manifestation includes abnormal metabolism of carbohydrates and lipids and inappropriate hyperglycemia that is caused …

5. Article

   Herbal therapy: A review of emerging pharmacological tools in the management of diabetes mellitus in Africa

   Cromwell Mwiti Kibiti, Anthony Jide Afolayan

   pp. 258–274 · DOI: 10.4103/0973-1296.166046 · Published 24 September 2015

   Background: Diabetes mellitus is a chronic physiological glucose metabolic disorder. It has affected millions of people all over the world thereby having a significant impact on quality of life. The management of diabete…

6. Article

   Xanthohumol induces apoptosis and S phase cell cycle arrest in A549 non-small cell lung cancer cells

   Wai Kuan Yong, Yen Fong Ho, Sri Nurestri Abd Malek

   pp. 275–283 · DOI: 10.4103/0973-1296.166069 · Published 24 September 2015

   Background: Xanthohumol, a major prenylated chalcone found in female hop plant, Humulus lupulus, was reported to have various chemopreventive and anti‑cancer properties. However, its apoptotic effect on human alveolar ad…

7. Article

   Neuroprotective effect of Citrus unshiu immature peel and nobiletin inhibiting hydrogen peroxide‑induced oxidative stress in HT22 murine hippocampal neuronal cells

   Hyun Woo Cho, Su Young Jung, Gyeong Hwan Lee, Jung Hee Cho, In Young Choi

   pp. 284–289 · DOI: 10.4103/0973-1296.166047 · Published 24 September 2015

   Background: Oxidative stress‑induced cell damage is common in the etiology of several neurobiological disorders, including Alzheimer’s disease and Parkinson’s disease. In a case study, nobiletin‑rich Citrus reticulata pe…

8. Article

   Selectivity of Pinus sylvestris extract and essential oil to estrogen‑insensitive breast cancer cells Pinus sylvestris against cancer cells

   Nguyen Thi Hoai, Ho Viet Duc, Do Thi Thao, Anne Orav, Ain Raal

   pp. 290–295 · DOI: 10.4103/0973-1296.166052 · Published 24 September 2015

   Background: So far, the anticancer action of pine tree extracts has mainly been shown for the species distributed widely around the Asian countries. Objective: Therefore, this study was performed to examine the potential…

9. Article

   Curcumin half analog modulates interleukin‑6 and tumor necrosis factor‑alpha in inflammatory bowel disease

   Phani Krishna Kondamudi, Hemalatha Kovelamudi, Pawan G. Nayak, Mallikarjuna Chamallamudi Rao

   pp. 296–302 · DOI: 10.4103/0973-1296.165991 · Published 24 September 2015

   Background: The present study was aimed at examining the effect of dehydrozingerone (DHZ), half analogue of curcumin which is the active constituent of turmeric (Curcuma longa) in the di‑nitrochlorobenzene (DNCB) induced…

10. Article

    Neuroprotective compounds of Tilia amurensis

    Bohyung Lee, Jin Bae Weon, Min Rye Eom, Youn Sik Jung, Choong Je Ma

    pp. 303–307 · DOI: 10.4103/0973-1296.166065 · Published 24 September 2015

    Background: Tilia amurensis (Tiliacese) has been used for anti‑tumor and anti‑inflammatory in Korea, China, and Japan. Objective: In this study, we isolated five compounds from T. amurensis and determined whether protect…

11. Article

    In vitro anti‑oxidant, cytotoxic and pro‑apoptotic effects of Achillea teretifolia Willd extracts on human prostate cancer cell lines

    Elif Burcu Bali, Leyla Açık, Pınar Elçi, Meral Sarper, Ferit Avcu, Mecit Vural

    pp. 308–315 · DOI: 10.4103/0973-1296.166060 · Published 24 September 2015

    Background: The majority of Achillea species are the most important native economic plants of Anatolia. They include highly bioactive compounds, so they have therapeutic applications. Objective: In the present study, the…

12. Article

    Reversed‑phase‑liquid chromatography method for separation and quantification of gallic acid from hydroalcoholic extracts of Qualea grandiflora and Qualea parviflora

    Mariana L. de Mesquita, Waleska F. Leão, Magda R. A. Ferreira, José E. de Paula, Laila S. Espindola, Luiz A. L. Soares

    pp. 316–321 · DOI: 10.4103/0973-1296.166062 · Published 24 September 2015

    Background: Qualea parviflora and Qualea grandiflora (Vochysiaceae), commonly known in Brazil as “pau‑terra” and “pau‑terrinha,” respectively, have been widely used in the treatment of ulcer and gastritis. These therapeu…

13. Article

    Anti‑inflammatory and cytotoxic activities of Bursera copallifera

    M. F. María C. Columba-Palomares, Dra. María L. Villareal, M. C. Macdiel E. Acevedo Quiroz, M. C. Silvia Marquina Bahena, Dra. Laura P. Álvarez Berber, Dra. Verónica Rodríguez-López

    pp. 322–328 · DOI: 10.4103/0973-1296.166067 · Published 24 September 2015

    Background: The plant species Bursera copallifera (DC) bullock is used in traditional medicine to treat inflammation.The leaves of this plant can be prepared as an infusion to treat migraines, bronchitis, and dental pain…

14. Article

    Apoptosis of AGS human gastric adenocarcinoma cells by methanolic extract of Dictamnus

    Hyun Soo Park, Noo Ri Hong, Tae Seok Ahn, Hyungwoo Kim, Myeong Ho Jung, Byung Joo Kim

    pp. 329–336 · DOI: 10.4103/0973-1296.165994 · Published 24 September 2015

    Background: The root bark of Dictamnus dasycarpus Turcz has traditionally been used in East Asia to treat skin diseases such as eczema, atopic dermatitis, and psoriasis. However, it has also been reported to exhibit an a…

15. Article

    Stability, clinical efficacy, and antioxidant properties of Honeybush extracts in semi‑solid formulations

    Gezina S. F. W. Gerber, Lizelle T. Fox, Minja Gerber, Jan L. du Preez, Sterna van Zyl, Banie Boneschans

    pp. 337–351 · DOI: 10.4103/0973-1296.166063 · Published 24 September 2015

    Background: Honeybush extracts (Cyclopia spp.) can be incorporated into skin care products to treat conditions such as skin dryness and can function as an anti‑oxidant. Objective: To formulate Honeybush formulations and …

16. Article

    Xanthii Fructus inhibits allergic response in the ovalbumin‑sensitized mouse allergic rhinitis model

    Nam‑Gil Gwak, Eun‑Young Kim, Bina Lee, Jae‑Hyun Kim, Yong‑Seok Im, Ka‑Yeon Lee, Chang Jun‑Kum, Ho‑Seok Kim, Hyun‑Joo Cho, Hyuk‑Sang Jung, Youngjoo Sohn

    pp. 352–361 · DOI: 10.4103/0973-1296.166058 · Published 24 September 2015

    Background: Xanthii Fructus (XF) is widely used in traditional anti‑bacterial and anti‑inflammatory Asian medicine. Allergic rhinitis is a common inflammatory disease characterized by markedly increased levels of anti‑in…

17. Article

    Chemical composition of the essential oil and fixed oil Bauhinia pentandra (Bong.) D. Dietr

    Macia C. S. Almeida, Luciana G. S. Souza, Daniele A. Ferreira, Francisco J. Q. Monte, Raimundo Braz-Filho, Telma L. G. Lemos

    pp. 362–364 · DOI: 10.4103/0973-1296.166015 · Published 24 September 2015

    Background: Bauhinia pentandra is popularly known as “mororó” and inhabits the Caatinga and Savannah biomes. Objective: This paper reports the chemical composition of the essential and fatty oils of the leaves from B. pe…