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    In vitro Screening for Antioxidant and Antimicrobial Properties of Three Lebanese Medicinal Plants Crude Extracts

    Josiane Alhage1, Hoda Elbitar1★★ Corresponding author

    1. 1AZM Centre for Research in Biotechnology and Its Applications, Laboratory of Applied Biotechnology for Biomolecules, Biotherapy and Bioprocess, Lebanese University, Tripoli, LEBANON.

    CORRESPONDENCE

    Hoda Elbitar

    AZM Centre for Research in Biotechnology and Its Applications, Laboratory of Applied Biotechnology for Biomolecules, Biotherapy and Bioprocess, Lebanese University, Tripoli, LEBANON.

    elbitarhoda@yahoo.fr

    Volume 11, Issue 2 · pp. 127–133 · PUBLISHED · DOI: 10.4103/pr.pr_171_18

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Background:Despite its small geographic area, Lebanon is characterized by a natural wealth in medicinal plants. Lebanese flora has about 2600 species, where >100 are endemic and are used in traditional medicine for their therapeutic effects. Objective: To evaluate the antioxidant and antimicrobial activities of dichloromethane, methanol, and aqueous crude extracts of three Lebanese medicinal plants: Geranium robertianum, Asphodelus microcarpus, and Alcea setosa. Materials and Methods: The antioxidant activity of different crude extracts was determined using the free radical, 1,1‑diphenyl‑2‑picrylhydrazyl. Antimicrobial activity was evaluated in a plate‑hole diffusion assay against two Gram‑negative (Pseudomonas aeruginosa and Escherichia coli) bacterial strains, one Gram‑positive (Staphylococcus aureus) bacterial strain, and a fungal strain (Candida albicans). Results:Methanol and aqueous extracts of G. robertianum possessed high scavenging activity (Radical scavenging activity ( RSA) >85%) at 0.3 mg/mL followed by the extracts of A. microcarpuswhich showed a moderate activity. G. robertianumextracts exhibited good inhibition diameters against S. aureus growth. Conclusion:Obtained results give an overall view on the bioactivities of three Lebanese medicinal plants crude extracts.

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      Alhage, J., & Elbitar, H. (). In vitro Screening for Antioxidant and Antimicrobial Properties of Three Lebanese Medicinal Plants Crude Extracts. Pharmacognosy Research, 11(2), 127–133. https://doi.org/10.4103/pr.pr_171_18