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    Article

    Phytochemical Screening and Bioactive Potential of Pod Seed Extracts of Leucaena leucocephala Linn

    Om Prakash1, Salma Malik2, Kumari Vandana Rani3, Vipin Kumar Verma2★★ Corresponding author

    1. 1Department of Zoology, Sri Venkateswara College, University of Delhi, New Delhi, INDIA.
    2. 2Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, INDIA.
    3. 3Department of Zoology, Kalindi College, University of Delhi, New Delhi, INDIA.

    CORRESPONDENCE

    Vipin Kumar Verma

    Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, INDIA.

    vipinkumarverma1@gmail.com

    Received: 05-06-2020; Revised: 15-07-2020; Accepted: 24-08-2020.

    Volume 12, Issue 4 · pp. 361–367 · PUBLISHED · DOI: 10.4103/pr.pr_49_20

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Background:Free radicals generated during injury lead to the development of various diseases such as diabetes, myocardial infarction, cerebrovascular disease, and cancer. Antioxidants present in plants can prevent the deleterious effect of these free radicals. Among various plants, Leucaena leucocephala is a mimosoid, fast‑growing, nitrogen‑fixing small tree having pods with various medicinal properties. Objective:Hence, the present study was designed to determine the bioactive potential of ethanolic and methanolic extracts of L. leucocephalapod seeds. Materials and Methods: We have assessed the antioxidant and antibacterial activities of the extract. In addition, the presence of various metabolites and other compounds was also evaluated though gas chromatography‑mass spectrometry (GC‑MS) analysis.Results:The results indicated that the methanol extract had relatively higher antibacterial and antioxidant properties than ethanol extract. Furthermore, GC‑MS data revealed the presence of various active constituents in the methanolic extract. Conclusion: Thus, the bioactive potential of various compounds present in methanol extracts of plant parts could be responsible for its antibacterial and antioxidant properties.

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      Prakash, O., Malik, S., Rani, K. V., & Verma, V. K. (). Phytochemical Screening and Bioactive Potential of Pod Seed Extracts of Leucaena leucocephala Linn. Pharmacognosy Research, 12(4), 361–367. https://doi.org/10.4103/pr.pr_49_20