Effect of Saleekha and Majeeth in Polycystic Ovarian Disease: An Open Observational Study
Shabnam Bano1★, Wajeeha Begum1, Syeda Sumaiya1★ Corresponding author
- 1Department of Ilmul Qabalat of Amraze Niswan, National Institute of Unani Medicine, Kottigepalya, Bengaluru, Karnataka, INDIA.
CORRESPONDENCE
Shabnam Bano
Department of Ilmul Qabalat of Amraze Niswan, National Institute of Unani Medicine, Kottigepalya, Bengaluru, Karnataka, INDIA.
Received: 26-08-2022; Revised: 23-09-2022; Accepted: 14-11-2022.
Volume 15, Issue 1 · pp. 168–175 · PUBLISHED · DOI: 10.5530/097484900240
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ABSTRACT
Introduction:PCOD is a common, complex reproductive endocrinopathy characterized by menstrual irregularities, hyperandrogenism, polycystic ovaries, metabolic and psychological disorders and affects up to 18% of reproductive-aged women. Objectives: To evaluate the effect of Saleekhaand Majeeth in PCOD. Materials and Methods: Clinically diagnosed Patients (n=30) with PCOD in age 18-35 years with oligomenorrhea or amenorrhoea were included in the study. Patients with thyroid dysfunction, systemic diseases, endometrial tuberculosis, malignancies on hormonal treatment in the last 3 months, pregnancy, and lactation were excluded. The research drug was administered orally in a dose of 3.5 gm B.D safūf (powder) ofSaleekhawith Joshānda(decoction) of Majeeth 7 gm BD for 14 days/ cycle for three consecutive cycles. Outcome measures were changes in subjective parameters (nature of bleeding, duration of cycles, duration of flow, amount of flow, weight reduction) and objective parameters, pictorial blood loss assessment chart (PBAC) score, basal metabolic index (BMI), modified Ferriman Gallwey (mFG) score, acanthosis nigricans scale and pelvic ultrasonography. Data were analyzed using the paired Student t-test. Results:Marked improvement was observed in menstrual irregularity and PBAC score with p<0.001 which is highly significant after the intervention. Significant change is seen in BMI, Ovarian volume, and SF-12 with p<0.001 after treatment. Safety parameters were within the normal range. Interpretation andConclusion:Research drugs (Saleekha and Majeeth) can be used as an alternate remedy in PCOD patients, as it significant effect to regularize menstruation by reduction of BMI and probably by improving insulin resistance in PCOD. No adverse effect of the research drug was noted during the trial.
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Bano, S., Begum, W., & Sumaiya, S. (). Effect of Saleekha and Majeeth in Polycystic Ovarian Disease: An Open Observational Study. Pharmacognosy Research, 15(1), 168–175. https://doi.org/10.5530/097484900240