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    Phytochemical Analysis of Selected Indigenous Plants and Essential Oils by Gas Chromatography/Mass Spectrometry Dedicate Antibacterial, Anti-Proliferative and Anti-Inflammatory Activity

    Fatma A. Eissa1, Taha A. Kumosani1,2,3★, Elie K. barbour3, Nouf O. Alshareef1, Khalid M. El-Say4, Said S. Moselhy5★ Corresponding author

    1. 1Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA.
    2. 2Production of Bio-products for Industrial Applications Research, King Abdulaziz University, Jeddah, SAUDI ARABIA.
    3. 3Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, SAUDI ARABIA.
    4. 4Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, SAUDI ARABIA.
    5. 5Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, EGYPT.

    CORRESPONDENCE

    Taha A. Kumosani

    Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA.

    tkumosani@kau.edu.sa

    Received: 03-12-2023; Revised: 08-02-2024; Accepted: 04-04-2024.

    Volume 16, Issue 4 · pp. 727–732 · PUBLISHED 1 October 2024 · DOI: 10.5530/pres.16.4.84

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Background:Natural compounds from medicinal plants have received much attention and research as resources in developing of new drugs. The challenge of for developing antibacterial agent from natural products for the treatment of MERSA, fungal and viral disease. Materials and methods:This study analyzed the chemical composition of Artemisia judaica and Juniperus procera methanol extracts and three essential oils include lemongrass (Cymbopogon citratus), clove (Syzygium aromaticum(L.) merr and perry) and tea tree (Melaleuca alternifolia). Results: The obtained results revealed the presence of bioactive functional molecules that exert several biological properties like antibacterial, anti-proliferative and anti-inflammatory activities such as caryophyllene, eugenol, palmitic acid and limonene. Conclusion: It was concluded that, it is promising in development of a novel plant-based drugs for MERSA, anti-inflammatory and antioxidant activities for mangment of different pathological conditions

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      Eissa, F. A., Kumosani, T. A., barbour, E. K., Alshareef, N. O., El-Say, K. M., & Moselhy, S. S. (2024). Phytochemical Analysis of Selected Indigenous Plants and Essential Oils by Gas Chromatography/Mass Spectrometry Dedicate Antibacterial, Anti-Proliferative and Anti-Inflammatory Activity. Pharmacognosy Research, 16(4), 727–732. https://doi.org/10.5530/pres.16.4.84