Volume 16, Issue 4

1 October 2024 · pp. 671–991 · 35 articles

Volume: 16
Issue: 4
Published: 1 October 2024
Pages: 671–991
Articles: 35
Sections: 2
ISSN: ISSN: Print - 0976-4836, Online - 0974-8490
Journal: Pharmacogn. Res.

Review Article Research Article

In this issue

Review Article

Review
A Review on the Utilization of Epicuticular Wax from Plant Samples as a Hydrophobic Surface Coating Agent
Nayan Talukdar, Manash Pratim Sarma, Akash Kalita, Trishna Sharma, Indrani Barman
pp. 671–676 · DOI: 10.5530/pres.16.4.78 · Published 1 October 2024
The rapid increase in pollution caused by plastic, especially packaging material, is raising concern across the globe. The statistics are only increasing with time, and without prompt action, this issue shows no signs of…
Review
HPLC Based Metabolomic Fingerprint Profiling as A Comprehensive Quality Assessment Tool, Why Not for Standardization of Ayurvedic Herbs and Formulations?
Nikunj Patel, Khushi Dave, Rinkal Patel, Kunjal Vegad, Niranjan Kanaki
pp. 677–687 · DOI: 10.5530/pres.16.4.79 · Published 1 October 2024
A global resurgence and rampant increase in the usage of herbal medicines has led to malpractices in the absence of adequate regulatory control to meet the growing demand. To ensure quality and hence efficacy, of these d…
Review
A Comprehensive Review on Ethnomedicinal Aspects, Phytochemical and Pharmacological Properties of Limonia acidissima Linn.
Salema Khatun, Saikat Sen
pp. 688–697 · DOI: 10.5530/pres.16.4.80 · Published 1 October 2024
Fruits and other parts ofLimonia acidissimaLinn. (Wood apple) is edible and used in different cuisines. In folk medicine, various plant parts are utilized to treat various ailments. In addition to being utilized as a fol…
Review
Unlocking the Therapeutic Potential of Terpenoids: A Roadmap for Future Medicine
Sarika Sapan Parekh, Ghanshyam Ratilal Parmar, Divya Kanojiya, Sunil Bhaurao Baile, Rahul Trivedi, Foram Bhatt
pp. 698–705 · DOI: 10.5530/pres.16.4.81 · Published 1 October 2024
The naturally produced plant-derived compounds, known as phytochemicals, are biologically effective and incorporated to reduce the risk of numerous human illnesses. The utilization of phytochemicals for traditional medic…
Review
Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents
Rajendra Prasad Menasagere Rajappa, Paramakrishnan Nallupillai, Kamsagara Linganna Krishna, Manoj Madanahalli Ramesh, Annegowda Hardur Venkatappa
pp. 706–717 · DOI: 10.5530/pres.16.4.82 · Published 1 October 2024
Herbal hepatoprotective drugs are important for managing liver health because they provide complementary or alternative treatments for the various disorders of the liver. This review provides a thorough analysis of the n…

Research Article

Article
Screening of in vitro Anticancer Activity of Various Human Cancer Cell Lines and Induced Apoptosis and Cell Arrest by Ethanolic Bulb Extract of Pancratium zeylanicum
Elumalai Shanthi Priya, Devaraj Sathiya Sheela, Devaraj Sheeba Gnanadeebam, Balrajmani Davidson Raja, Periannan Viswanathan
pp. 718–726 · DOI: 10.5530/pres.16.4.83 · Published 1 October 2024
Aim:World widely the human society suffers from various types of cancer due to many causes. Thus, finding out a good anticancer agent is a need of the hour. Medicinal herbs are always considered at pole position whenever…
Article
Phytochemical Analysis of Selected Indigenous Plants and Essential Oils by Gas Chromatography/Mass Spectrometry Dedicate Antibacterial, Anti-Proliferative and Anti-Inflammatory Activity
Fatma A. Eissa, Taha A. Kumosani, Elie K. barbour, Nouf O. Alshareef, Khalid M. El-Say, Said S. Moselhy
pp. 727–732 · DOI: 10.5530/pres.16.4.84 · Published 1 October 2024
Background:Natural compounds from medicinal plants have received much attention and research as resources in developing of new drugs. The challenge of for developing antibacterial agent from natural products for the trea…
Article
Evaluation of Balya Activity of Atibala (Abutilon indicum (Linn.) Sw) in Cisplatin-Induced Muscle Atrophy Model
Vishala Hiremath, Vedantam Giridhar, Santosh F Patil, Ranjit Kangle
pp. 733–740 · DOI: 10.5530/pres.16.4.85 · Published 1 October 2024
Background: Cisplatin, an antineoplastic drug, induces muscle atrophy in patients. Given this, investigating potential interventions such as nutritional supplements or medications to regulate catabolic processes, cellula…
Article
Comprehensive Phytochemical Profiling and Antiphage Activity of Methanolic Extract of Withania somnifera against Lactic Acid Bacteriophages
Mulay Rutam, Zarine P Bhathena
pp. 741–747 · DOI: 10.5530/pres.16.4.86 · Published 1 October 2024
Introduction:Bacteriophages present a significant challenge to commercial dairy manufacturing facilities impacting product quality and causing great economic losses to the dairy industry. Despite routine phage control me…
Article
Protective Activity of Rumex vesicarius Leaf Extract on Doxorubicin Induced Cardiotoxicity
Mitta Raghavendra, Pulala Raghuveer Yadav, Mondi Sushma, Vallala Venkata Rajesham, Pinjari Roshan Ali, Panchareddy Nikitha, Tadikonda Rama Rao
pp. 748–756 · DOI: 10.5530/pres.16.4.87 · Published 1 October 2024
Background: Doxorubicin is an important and efficient anticancer medicine that is widely used to treat several types of cancer. However, its clinical use is limited due to dose-dependent cardiotoxicity. Elevated tissue l…
Article
Chemical Profiling, Chromatographic Fingerprinting and Anthelmintic Screening of a Rare Species of Holly, Ilex khasiana Purkay.from Mizoram, Northeast India
Charles Lalnunfela, Pawi Bawitlung Lalthanpuii, Hmar Tlawmte Lalremsanga, Tochhawng Lalhriatpuii, Kholhring Lalchhandama
pp. 757–768 · DOI: 10.5530/pres.16.4.88 · Published 1 October 2024
Background:I. khasiana Purkay. is an evergreen tree of the family Aquifoliaceae and is classified critically endangered as only few of them are identified in Northeast India. In Khasi traditional medicine, it is used for…
Article
Ethnomedicinal Plants, Associated Indigenous Knowledge and Phytochemical Composition of Extracts with Significant in vitro Antidiabetic Activity
Pardon Mugari, Stephen Nyon, Pamhidzai Dzomba
pp. 769–783 · DOI: 10.5530/pres.16.4.89 · Published 1 October 2024
Background: Despite increasing popularity of ethnomedicinal plants in diabetes type 2 management nowadays, indigenous knowledge of their use is often not documented but rather passed on orally from generation to generati…
Article
Investigating Dioscorea polystachya Starch as a Pharmaceutical Excipient
Vijayan Venugopal, Jaiganesh Krishnan, Lim Hui Feng, Ang Li Ni, Venkates Kumar, Gunasunderi Raju
pp. 784–792 · DOI: 10.5530/pres.16.4.90 · Published 1 October 2024
Background: Dioscorea polystachya (DP) starch, a low-cost, abundant, renewable and degradable starch, is being explored as a potential pharmaceutical excipient for drug formulation.Objectives: This study aimed to explore…
Article
Rosa indica Leaf Contains Molecules with Promising Antioxidant, Antimicrobial and Anticancer Effects in vitro with Strong Interaction with Human VEGFR2 in silico
Sini Hariharan, Neema Job, Kottayath Govindan Nevin, Arun Kumar Gangadharan
pp. 793–802 · DOI: 10.5530/pres.16.4.91 · Published 1 October 2024
Background:Plants-based compounds/biopharmaceuticals are found to be effective against multiple ailments due to their fewer side effects. Objectives: In this study, the antioxidant, antibacterial and cytotoxic properties…
Article
Exploring Antidepressant and Skeletal Muscle Relaxant Effects of the Hydroalcholic Extract of the Sedum lineare Thunb
Sunil Kumar, Ajay Kumar Singh Rawat, Peeyush Bhardwaj
pp. 803–809 · DOI: 10.5530/pres.16.4.92 · Published 1 October 2024
Background: Sedum lineare is a perennial succulent plant that is a member of the family Crassulaceae. Objectives:The present study desired to explore the antidepressant and muscle relaxant activities of hydroalcoholic ex…
Article
Investigation of Medicinal Plants Used to Treat Malaria by the Ethnic People of Purulia District, West Bengal, India
Rajani Kanta Mahato, Arup Kumar Mandal, Shyamal Kanti Mallick, Arijit Sinhababu
pp. 810–816 · DOI: 10.5530/pres.16.4.93 · Published 1 October 2024
Background: One of the most prevalent serious medical issues worldwide is Malaria. It is caused by different Plasmodium sp. and can infect people by the bite of a female Anopheles sp. mosquito. It is important to explore…
Article
Exploring the Antioxidant and Antiproliferative Properties of Four Medicinal Plants from Veracruz, Mexico for Urinary and Prostate Health
Oscar Antonio Sánchez-Aguirre, Cynthia Fernández-Pomares, Enrique Juárez-Aguilar, Alberto Sánchez-Medina, Leticia Margarita Cano-Asseleih
pp. 817–827 · DOI: 10.5530/pres.16.4.94 · Published 1 October 2024
Background: C. scaber, P. aequale, S. oleraceus and S. racemosa play a vital role in traditional medicine in Veracruz, Mexico, known for their effectiveness in treating a wide range of health issues. Particularly notewor…
Article
Histological Analysis Reveals that Red Grape Seed Extract (Vitis vinifera L.) Rejuvenates Antioxidant Enzymes in Male Albino Rats (Wistar strain) with D-Galactose-Induced Alzheimer's Disease (AD) Brain Regions
V. Uday Kiran, H. Ramasubba Reddy, P. Ramesh Kumar, M. Muniya Naik, C. Narasimha Rao, A. Jayasankar, C. Aruna, D. Veera Nagendra Kumar
pp. 828–836 · DOI: 10.5530/pres.16.4.95 · Published 1 October 2024
Aim:Oxidative stress is a significant risk factor for Alzheimer’s Disease (AD) as it promotes lipid peroxidation and diminishes antioxidants in the nervous system. This study investigates the effect of Red Grape Seed Ext…
Article
Modification and Physicochemical Evaluation of Naque Nazla a Unani Infusion Preparation for Cold and Flu into Soluble Granules
Mohammad Zaigham, Hamiduddin h, Mohd Akhtar Ali, Mohammed Abdul Waheed
pp. 837–853 · DOI: 10.5530/pres.16.4.96 · Published 1 October 2024
Background:Infusions and decoctions for Nazla/Zukam (Cold and Flu) are time tested in Unani System of Medicine. Naque Nazla (NN) Infusion containing Viola odorataLinn. flower,Zizyphus jujuba Linn. fruit, Cordia dichotama…
Article
Analysis of Volatile Compounds in Caulerpa lentillifera for Anti-Proliferative Studies in HEPG2 Liver Cancer Cells and in silico Comparison
Rammiya Rajasegaran, Asita Elengoe, Sau Pin Woo, Muhammad Ariffuddin Abd Hamd, Noorfatimah Yahaya, Shahrul Hamid
pp. 854–860 · DOI: 10.5530/pres.16.4.97 · Published 1 October 2024
Background: Liver cancer remains a significant cause of mortality despite standard therapies. Recent studies have highlighted the anti-inflammatory properties and cancer prevention potential of certain agents. Caulerpa l…
Article
Determination of Dried Root Extract of Rheum emodi and its Commercial Products Using Rhein and Chrysophanol as Standard Markers by HPTLC Densitometric Analysis
Rizwan Ahmad, Zeeshan Fatima, Sadath Ali, Suneela Dhaneshwar, Sayeed Ahmad
pp. 861–871 · DOI: 10.5530/pres.16.4.98 · Published 1 October 2024
Background:Standardization and quality control of medicinal plants and their commercial products are one of the critical needs for ensuring their quality, safety and efficacy which assists in validation as well as regula…
Article
Development and Evaluation of Herbal-Enriched Nutraceutical Gummies for Pediatric Health
Kanchana Yadav, Nitin Motiram Gawai, Brijesh Shivhare, Laxman Sureshbabu Vijapur, Gaurav Tiwari
pp. 872–878 · DOI: 10.5530/pres.16.4.99 · Published 1 October 2024
Background: Nutraceuticals, which combine the nutritional benefits of food with the therapeutic effects of pharmaceuticals, offer a promising approach to enhancing children's health and well-being. Among these, herbal-en…
Article
Enhanced Antifungal Efficacy of KZ-β/γ-CD Capped Silver Nanoparticles against Trichophyton rubrum
Bhargavi Kumaraswamy, Sunil More, Aneesa Fasim, Raju Koneri
pp. 879–886 · DOI: 10.5530/pres.16.4.100 · Published 1 October 2024
Background:The present medications are inefficient in treating fungal infections, so there is a need to develop an efficient antifungal treatment with minimal side effects and rapid healing. Ketoconazole (KZ) is frequent…
Article
Melezitose a Potential of Bioactive Compound from Aqueous Extract of Indian Satavari: An Web Based in silico Study Utilizing GC-MS Analysis
Sandip Sen, Kalepu Swathi, Dubbasi Vishwanath, Bairam Ravindar, Mitta Chaitanya, Srinivas Cherukupally, Shapuram Tejasree, Hema Varaha Santhoshi Allu
pp. 887–896 · DOI: 10.5530/pres.16.4.101 · Published 1 October 2024
Background:Historical records indicate that medicinal plants and their components have been utilized for treating diverse conditions since antiquity. Asparagus racemosus, in particular, demonstrates a broad spectrum of t…
Article
Evaluation of Fractions of Artocarpus lakoocha R. on Doxorubicin Induced Myocardial Toxicity in Wistar Rats
Shreya Nagmoti, Shrishail K. Nimbal, Hasanpasha N. Sholapur, Navya S, Siddalingaswamy Hiremath
pp. 897–907 · DOI: 10.5530/pres.16.4.102 · Published 1 October 2024
Background: Doxorubicin, an anthracycline derivative, is a cytotoxic drug that has been shown to be effective against a variety of cancers. Its clinical utility has been limited due to dose-dependent cardiac toxicity. Ob…
Article
Evaluating Bioactive Potential of Lichen Secondary Metabolites for the Formulation of Mosquito Repellent
Shanmugam Poornima, Vivekanandhan Vidhya Sree, Jaganathan Geethanjali, Rajamanickam Karishma, Moorthy Viksha, Balasubramani Suresh Gopi, Ganesan Kishore
pp. 908–916 · DOI: 10.5530/pres.16.4.103 · Published 1 October 2024
Background:Mosquitoes belong to the major disease transmitters causing millions of deaths every year. The cost of commercially available pyrethroids, environmental regulations and toxicity of commercial repellents force …
Article
Formulation and Evaluation of Jatropha curcas Latex Based Gel for the Treatment of Canker Sores
Shanmugam Poornima, Manickam Sanjeev Kumar, Palanisamy Divya, Balasubramani Suresh Gopi, Ganesan Kishore, Srinivasan Naresh, Balachandiran Harinidevi
pp. 917–922 · DOI: 10.5530/pres.16.4.104 · Published 1 October 2024
Background:The recent food habits of the people causing severe health issues. One of the most relevant oral problems that disturb the daily life of the people is canker sores. The latex of Jatropha curcas can be used as …
Article
Evolution and Confirmation of UV Spectrophotometric Approach for Simultaneously Estimating Allicin and Azadirachta indica Extracts in Niosomal Formulation
Shilpa Pravin Chaudhari, Abhishek Sunil Nemmaniwar, Sarika Ankushrao Nikam
pp. 923–928 · DOI: 10.5530/pres.16.4.105 · Published 1 October 2024
Background:Generally, it is quite difficult to precisely tell the exact amount of drug in any formulation after formulating it using the active ingredient and other excipients.Aim:Based on the simultaneous equation metho…
Article
High-Performance Thin Layer Chromatography (HPTLC) Analysis for the Quantification of Constituents in Ficus religiosa
Jyothisree Gangadharan, Umadevi Sankararajan
pp. 929–934 · DOI: 10.5530/pres.16.4.106 · Published 10 October 2024
Background: Ficus religiosa, revered for its medicinal properties in traditional medicine, has drawn scientific interest due to its diverse chemical composition. This study aimed to develop a densitometric High-Performan…
Article
Evaluating the Efficacy of a Ginger Extract-Infused Mustard Oil Transdermal Patch for Arthritis Management
Arpitha Jayatheertha Lokapur, Vedamurthy Joshi
pp. 935–942 · DOI: 10.5530/pres.16.4.107 · Published 1 October 2024
Aim: The aim of this study is to develop and characterize a novel herbal transdermal patch containing mustard oil and ginger extract for the management of arthritis, addressing the significant pain and reduced quality of…
Article
Controlling of Oral Pathogens and Anti-Inflammatory Activity of Copper Oxide Nanoparticles Synthesized Using Cymbopogon citratus and Zingiber officinale
Rajeshkumar Shanmugam, Rohit Ravikumar, Ashwin Senthil Kumar, Jayasree Anandan, Akshetha Loganathan, Kushi Jain
pp. 943–948 · DOI: 10.5530/pres.16.4.108 · Published 1 October 2024
Introduction: Green chemistry is considered a preferable alternative to hazardous chemical compounds when it comes to producing non-toxic nanomaterials. Copper Oxide Nanoparticles (CuONPs) are well-known for its antimicr…
Article
Profiling of Iron Weed: An Ethnopharmacological Approach
Saloni Kothari, Devangi Chachad
pp. 949–967 · DOI: 10.5530/pres.16.4.109 · Published 20 October 2024
Background: Baccharoides anthelmintica L., known as Iron weed or Kali Jeeri, is a traditional medicinal plant used for treating asthma, sores, inflammation, and various other ailments. It boasts pharmacological activitie…
Article
Evaluation of Wound Healing Activity of Polyherbal Gel Containing Azadirachta indica, A. Juss. and Tridax procumbens L. Extracts
Suraj Bhivasan Satpute, Aishwarya Ramchandra Balap
pp. 968–976 · DOI: 10.5530/pres.16.4.110 · Published 3 October 2024
Background: Azadirachta indicaA. Juss. and Tridax procumbens L. have been utilized for wound management and therapy since ancient times and offer huge potential.Objectives: To formulate polyherbal gel containing Azadirac…
Article
Antioxidant and Anti-Inflammatory Impact of Jujuboside B on LPS-Stimulated RAW 264.7 Cells
Faiz Abdulaziz Alfaiz
pp. 977–984 · DOI: 10.5530/pres.16.4.111 · Published 3 October 2024
Aim: Zizyphus jujuba Mill, a well-known traditional Eastern medicine, has been documented to display a variety of biological system-related actions. Zizyphus jujuba fruits contain a natural saponin called jujuboside B (J…
Article
Antimicrobial, Phytochemical Screening and GC-MS Analysis of Ruta chalepensis L. Leaves and Stems Extracts
Sara Hussein Altayeb, Fatima Abdalgalill Khleefa, Solima Ibrahim Yagoob, Rasha Abdelnaser Abdelhadi, Omrana Ahmad Kamli, Husham Elraih Homeida, Asaad Khalid Ahmed, Noha Abdullah Arishi, Lolah Nasser Ogdi
pp. 985–991 · DOI: 10.5530/pres.16.4.112 · Published 1 October 2024
Background: Ruta chalepensisL. is considered as a medicinal plant with many important secondary metabolites and essential oils which widely used against many diseases. Objectives:This study aimed to examine different pol…