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    GC-MS Analysis of Bioactive Compounds Present in the Different Extracts of the Whole Plant Impatiens minor (DC.) Bennet

    Akila Sukumaran1, Ansa Mathew2, Sebastin Varghese3, Ajithbabu Tharackal Kannankutty3 Corresponding author

    1. 1Department of Pharmacognosy, Malik Deenar College of Pharmacy, Seethangoli, Kasaragod, Kerala, INDIA.
    2. 2Department of Pharmacognosy, Dr. Joseph Mar Thoma Institute of Pharmaceutical Sciences and Research, Kayamkulam, Alappuzha, Kerala, INDIA.
    3. 3Department of Pharmaceutical Chemistry, Malik Deenar College of Pharmacy, Seethangoli, Kasaragod, Kerala, INDIA.

    CORRESPONDENCE

    Akila Sukumaran

    Associate Prof. Akila Sukumaran, Department of Pharmacognosy, Malik Deenar College of Pharmacy, Seethangoli, Kasaragod, Kerala, INDIA.

    akhilasuku@yahoo.com

    Received: 24-09-2024; Revised: 04-11-11; Accepted: 06-12-2024.

    Volume 17, Issue 1 · pp. 126–132 · PUBLISHED 2025 · DOI: 10.5530/pres.20251952

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Background and Objectives The systematic assessment of herbs utilized in the traditional medicine could provide more promising data regarding their therapeutic properties helping to address the increasing need for innovative treatments for infections and illnesses. Considering this perspective, Impatiens minor, an important medicinal plant distributed in the wet wastelands throughout India and also in the wet forests of Western Ghats was selected for our research. Materials and Methods In this study, the plant I. minor in whole was collected, authenticated and subjected to shade drying for powdering which was done by mechanical grinder. Soxhlation technique was employed for the extraction of powdered plant material using different solvents to prepare the dried extract which was subjected to preliminary phytochemical evaluation and GC-MS analysis. Results Presence of glycosides, phenolic compounds, flavonoids, terpenoids, sterols and carbohydrates was found in the preliminary phytochemical evaluation of different extracts. In the GC-MS analysis, presence of eight major compounds were found in the petroleum ether extract, while the chloroform extract showed the presence of six major compounds and twelve major compounds were found in the ethanol extract. Conclusion It is worth noting that certain compounds identified in the GC-MS analysis have been documented to possess anti-oxidant, anti-inflammatory, and anticancer properties in previous studies. This study has the potential to contribute valuable insights for future in-depth investigations.

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      Sukumaran, A., Mathew, A., Varghese, S., & Kannankutty, A. T. (2025). GC-MS Analysis of Bioactive Compounds Present in the Different Extracts of the Whole Plant Impatiens minor (DC.) Bennet. Pharmacognosy Research, 17(1), 126–132. https://doi.org/10.5530/pres.20251952