An in vitro evaluation of the anthelmintic activity of Hedychium spichatum rhizomes and Zingiber zerumbet rhizomes on the Pheritima Posthuma model: A comparative study
Shambaditya Goswami1★, Awanish Pandey1, Poonam Tripathi1, Asheesh Singh1, Amrita Rai1★ Corresponding author
- 1Department of Pharmacy, Institute of Technology and Management, Gorakhpur, India
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Shambaditya Goswami
*Address for correspondence: Mr. Shambaditya Goswami, Department of Pharmacy, Institute of Technology and Management, Faculty Residence, Block-C, AL-, SEC-7, GIDA, Gorakhpur, India.
Revised: 11-11-2010.
Volume 3, Issue 2 · pp. 140–142 · PUBLISHED January 2011 · DOI: 10.4103/0974-8490.81963
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ABSTRACT
Ethanolic extracts of Hedychium spichatum rhizomes and Zingiber zerumbet rhizomes were taken for in vitro comparative studies on the anthelmintic activity against Pheritima posthuma. Different concentrations (25, 50, 100 mg/ml) of both the extracts were used for the activity. Varying albendazole concentrations (25, 50, 100 mg/ml) were used as a reference standard and normal saline (0.9% NaCl) was used for the control treatment. The results were expressed in terms of time in minutes to report the paralysis and time of death of the earthworms. The results obtained from the study indicate toward the anthelmintic activity, supporting folk use of both the plants when compared with the standard. The results also established that Z. zerumbet was a more potent candidature of as compared with H. spichatum.
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Goswami, S., Pandey, A., Tripathi, P., Singh, A., & Rai, A. (2011). An in vitro evaluation of the anthelmintic activity of Hedychium spichatum rhizomes and Zingiber zerumbet rhizomes on the Pheritima Posthuma model: A comparative study. Pharmacognosy Research, 3(2), 140–142. https://doi.org/10.4103/0974-8490.81963