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    GC-MS analysis of bioactive compounds in the methanol extract of Clerodendrum viscosum leaves

    Goutam Ghosh1★, Pritipadma Panda1, Meera Rath2, Abhisek Pal2, Tripti Sharma3, Debajyoti Das1★ Corresponding author

    1. 1Department of Pharmacognosy, School of Pharmaceutical Sciences
    2. 2Departments of Pharmacology
    3. 3Departments of Medicinal Chemistry, Institute of Medical Science, Siksha ‘O’ Anusandhan University, Bhubaneswar, Odisha, India

    CORRESPONDENCE

    Goutam Ghosh

    *Address for correspondence: Dr. Goutam Ghosh, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan University, Khandagiri Square, Bhubaneswar - 751 003, Odisha, India.

    goutamghoshsps@gmail.com

    Revised: 13-07-2014.

    Volume 7, Issue 1 · pp. 110–113 · PUBLISHED January-March 2015 · DOI: 10.4103/0974-8490.147223

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Background Clerodendrum viscosum is commonly found in India and Bangladesh. Previously, various parts of this plant were reported for treatment of different types of diseases and there was no report on GC-Ms analysis. Objective To analyze and characterize the phytochemical compounds of methanol extract of Clerodendrum viscosum using GC-MS. Materials and Methods The preliminary phytochemical screening of methanol extract was carried out according to standard procedures described in WHO guidelines. Various bioactive compounds of the extract were determined by GC-MS technique. Results The presence of steroids, triterpenoids, alkaloids, saponins, flavonoids, tannins and carbohydrate was found on phytochemical screening of methanol extract of the leaves. The GC-MS analysis showed 16 peaks of different phytoconstituents namely acetamide,N,N-carbonylbis-, 4-Pyranone,2,3-dihydro-, alpha-D-Galactofuranoside, methyl 2,3,5,6-tetra-O-methyl-, Glycerin, Xylitol, N,N-Dimethylglycine, 4H-Pyran-4-one,2,3-dihydro-3, 5-dihydroxy-6- methyl-, Benzofuran,2,3-dihydro-, 5-Hydroxymethylfurfural, 2(1H)Pyrimidinone,1-methyl-, 2,4-Dihydroxy-5,6-dimethylpyrimidine, 3-Deoxy-d-mannoic lactone, 1,3-Methylene-d- arabitol, Orcinol, n-Hexadecanoic acid and Phenol,4,4'-(1-methyl ethylidene) bis etc. Conclusion The bioactive compounds present in the methanol extract of Clerodendrum viscosum suggest the application of this extract for the treatment of various diseases by the aborigine tribes.

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      Ghosh, G., Panda, P., Rath, M., Pal, A., Sharma, T., & Das, D. (2015). GC-MS analysis of bioactive compounds in the methanol extract of Clerodendrum viscosum leaves. Pharmacognosy Research, 7(1), 110–113. https://doi.org/10.4103/0974-8490.147223