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    Free Radicals and AntioxidantsNOW IN
    Article

    Evaluation of Antioxidant Properties in Thirteen Fijian Medicinal Plants Used in Alzheimer’s Disease and Related Illness

    Ranish Nitesh Chand1,2, Romila Devi Gopalan1★, Ketan Christi1★ Corresponding author

    1. 1School of Biological and Chemical Sciences, Faculty of Science, Technology and Environment, The University of the South Pacific, Suva, FIJI..
    2. 2Senior Education Officer Research, Ministry of Education Heritage and Arts, FIJI..

    CORRESPONDENCE

    Romila Devi Gopalan

    School of Biological and Chemical Sciences, Faculty of Science, Technology and Environment, The University of the South Pacific, Suva, FIJI..

    devi_rd@usp.ac.fj

    Received: 18-04-2017; Revised: 27-05-2017; Accepted: 15-06-2017.

    Volume 8, Issue 1 · pp. 11–17 · PUBLISHED · DOI: 10.5530/fra.2018.1.3

    View on Free Rad. Antiox. original site ↗

    ABSTRACT

    Objective: The present study aims to evaluate antioxidant properties of decoction and ethanol extracts of Fijian medicinal plants using 2,2-diphenyl-1-picryl-hydrazyl (DPPH) scavenging assay. Method: Thirteen plant species belonging to Melastomataceae, Asteraceae, Apiaceae, Rutaceae, Goodeniaceae, Loganiaceae, Araliaceae, Solanaceae, Polygonaceae, Zingiberaceae and Anacardiaceae families were tested at 0.2 mg/mL, 0.4 mg/mL, 0.6 mg/mL, 0.8 mg/mL, 1.0 mg/mL, 1.5 mg/mL and 2.0 mg/mL concentrations for antioxidant properties. The antioxidant capabilities were compared with ascorbic acid standard.Results and Discussions: Among the decoction and ethanol extracts tested, all plants showed DPPH scavenging activity. The most potent antioxidant activity was seen in C. hirta with an IC50 value of 0.64 mg/mL. The activity ofC. hirta was twofold more potent than the standard ascorbic acid (IC50 = 1.33 mg/mL) indicating that polar extracts of C. hirta contains compounds with relatively better antioxidant properties than ascorbic acid.Conclusion: The plant extracts used in this study were crude extracts, as it is envisaged that if the phytochemicals were isolated and purified from these plants, more prominent results could be expected. These plants could prove leads to safer and better candidates for the future selection of antioxidant.

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        Chand, R. N., Gopalan, R. D., & Christi, K. (). Evaluation of Antioxidant Properties in Thirteen Fijian Medicinal Plants Used in Alzheimer’s Disease and Related Illness. Free Radicals and Antioxidants, 8(1), 11–17. https://doi.org/10.5530/fra.2018.1.3