Cover: Free Radicals and Antioxidants
Free Radicals and Antioxidants
Volume 16, Issue 1
2026 · pp. 1–33 · 7 articles
- Volume
- 16
- Issue
- 1
- Published
- 2026
- Pages
- 1–33
- Articles
- 7
- Sections
- 4
- ISSN
- 2231-2536
- Journal
- Free Rad. Antiox.
In this issue
Review Article
- Review
Oxidative Stress Modulation in Chronic Rhinosinusitis with Nasal Polyps: Mechanistic Perspectives on Teucrium marum Varum
Mukesh Maity, Krishna Chandra Maity, Saikat Hazra, Arnab Kheto, Samik Banerjee, Sinchan Das
pp. 1–11 · DOI: 10.5530/fra.20260001 · Published 2026
It is becoming more well recognized that Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a self-sustaining mucosal ecosystem in which oxidant-antioxidant imbalance, microbial dysbiosis, stromal remodeling, type 2 im…
Original Article
- Article
Effect of the Ethanolic Extract of the Rhizome of Gastrodia elata on Spermatogenesis in Male Sprague-Dawley Rats
Chai Zi Wei, Chuah Jia Jun, Subramani Parasuraman
pp. 12–17 · DOI: 10.5530/fra.20260002 · Published 2026
Background: Gastrodia elata is a traditional Chinese herb used to treat neurological disorders. Gastrodin, its main bioactive component, has been extensively studied for pharmacological effects. This study aimed to evalu…
- Article
Hypoglycemic, Hypolipidemic and Antioxidant Effects of Chloroform Seed Extracts of Three Cleome Species and their Synergistic Combination in Streptozotocin-Induced Diabetic Rats
Pounraj Kanimathi, Karanam Satya Ramya, Rose Mary Kiriyanthan, Arunachalam Radha
pp. 18–25 · DOI: 10.5530/fra.20260003 · Published 2026
Background: Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia, dyslipidaemia, oxidative stress, and progressive tissue damage. This study evaluated the antidiabetic, hypolipidaemic, and an…
Commentary
- Article
Hormesis in Motion: Exercise-Induced Oxidative Stress and the Case Against Antioxidant Supplementation in Athletes
Mueen Ahmed KK
pp. 26–27 · DOI: 10.5530/fra.20260004 · Published 2026
Exercise has long been framed as a double-edged metabolic sword. Vigorous muscular contraction increases mitochondrial oxygen flux and generates Reactive Oxygen Species (ROS) at rates well above resting baseline, and for…
- Article
Diet, Oxidative Stress, and Healthy Aging: Separating Whole-Food Evidence from Supplement Hype
Mohammed Yunus, Mueen KK Ahmed
pp. 28–29 · DOI: 10.5530/fra.20260005 · Published 2026
The marketing logic behind antioxidant supplements is intuitive almost to the point of being seductive: oxidative stress contributes to aging and disease, fruits and vegetables contain antioxidants, therefore concentrate…
- Article
The Antioxidant Paradox in Cancer: When Neutralizing Free Radicals Protects the Tumor
Mueen Ahmed KK
pp. 30–31 · DOI: 10.5530/fra.20260006 · Published 2026
For half a century, the public has absorbed a simple message: free radicals damage DNA, DNA damage causes cancer, and antioxidants mop up free radicals-therefore antioxidants should prevent cancer. The logic is so intuit…
Letter to the Editor
- Article
significant dose-response relationship emerging above roughly 150 IU/day, leading the authors to recommend that high-dosage Vitamin E be avoided. This is not a marginal caveat; it is a direct contradiction of the protective benefit that such products imply. The pattern extends well beyond a single nutrient. According to PubMed, a systematic review and meta-analysis spanning 884 randomized trials and more than 880,000 participants reported
Mueen Ahmed KK
pp. 32–33 · DOI: 10.5530/fra.20260007 · Published 2026
Antioxidant dietary supplements continue to be marketed to the public with broad implications of disease prevention and “healthy aging,” yet the weight of randomized evidence has not kept pace with the confidence of the …