Volume 17, Issue 2

2026 · pp. 161–314 · 17 articles

Volume: 17
Issue: 2
Published: 2026
Pages: 161–314
Articles: 17
Sections: 3
ISSN: ISSN: Print - 0976-500X, Online - 0976-5018
Journal: J Pharmacol. Pharmacother.

Review Article Original Research Article Case Report

In this issue

Review Article

Review
Diabetes Mellitus-related Pathogeny: A Precipitating Factor for Alzheimer’s Disease—An Insight on Repurposing Diabetes Pharmacological Treatments in Alzheimer’s Disease
Chiamaka Onyekwuluje, Nokwanda Ngcobo, Ntethelelo Sibiya
pp. 161–173 · DOI: 10.1177/0976500X251365078 · Published 2026
Background: The brain, through the sensory action of neurons situated in the hypothalamus and brainstem, plays a pivotal role in the homeostatic regulation of glucose metabolism. The brain senses changes in nutrients and…
Review
Clinical Frontiers of Exosome Research: A Comprehensive Analysis of Human Trials in Diagnostics, Therapeutics, and Regenerative Medicine
Syam Mohan, Nizar A. Khamjan, Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Jobran M. Moshi, Abrar Fahad Alshahrani, Jeraiby A. Mohammed, Saeed Alshahrani, Khaled A. Sahli, Hatem Ahmed Salem Alqhtani, Muhammad H. Sultan, Marwa Qadri, Ali Ibrahim Ali Ashgar, Abdullah Farasani, Hussain Ali I. Shobaili, Abdualmagid Mohammed Tobaiqi, Tariq Idris Somily
pp. 174–190 · DOI: 10.1177/0976500X251361201 · Published 2026
Background: Exosomes, key mediators of intercellular communication, transport functional biomolecules, making them promising tools for diagnostics and therapeutics across various human diseases. Objectives: To systematic…

Original Research Article

Article
Partial Purification and Characterizations of Bacteriocin from Lactobacillus casei Isolated from Goat Milk: A Novel Antimicrobial Agent
Jumaila Kooriparambil, Vijaya Chitra Arumugam, Vajid Nettoor Veettil, Shamla Alikadavath
pp. 191–198 · DOI: 10.1177/0976500X251347425 · Published 2026
Purpose/Background: This study aimed to isolate, purify, and characterize a novel bacteriocin produced by Lactobacillus casei strain GO3, isolated from goat milk. Bacteriocins are promising natural antimicrobial agents w…
Article
Perception of MBBS Students About Pharmacology Teaching in New Competencybased Medical Education (CBME) Curriculum at a Tertiary Care Medical Institute of Haryana
Jyoti Sharma, Himani Deswal, Jyoti Kaushal, Suneel Rohilla
pp. 199–205 · DOI: 10.1177/0976500X251336881 · Published 2026
Background: Competency-based medical education (CBME) is an approach that ensures that the focus of teaching, learning, and assessment is on real-life medical practice. There is a radical shift in the teaching, learning,…
Article
Intranasal Application of Ubrogepant Nanoparticles Improve the Brain Penetration and Efficacy in Migraine
Vignesh Mohan, Anil M. Pethe
pp. 206–213 · DOI: 10.1177/0976500X251336879 · Published 2026
Background: Ubrogepant is a successful drug used for the therapy of migraine. Objectives: The objective of this work was to formulate a novel nanoparticle-based therapy using ubrogepant for optimum therapeutic efficacy b…
Article
Evaluation of Potential Drug–Drug Interactions in Cardiac Inpatients at a Tertiary Care Hospital: A Cross-sectional Study Pushpa V. H.1 , Shurti Pareek1 , Manjappa M.2 , Ranjith Raj1 , Sulochanadevi B. C.3
and Vidya Gowdappa Doddawad
pp. 214–219 · DOI: 10.1177/0976500X251371105 · Published 2026
Background: Drug–drug interactions (DDIs) are a significant concern among cardiac inpatients, potentially impacting therapeutic outcomes and patient safety. Early identification and management of potential DDIs are cruci…
Article
Optimizing Geriatric Prescriptions: Development, Validation, and Pilot Testing of Novel Quality Assessment Tool
Danisha Pattani, Dilip Chandrasekhar
pp. 220–230 · DOI: 10.1177/0976500X251345885 · Published 2026
Background: Prescriptions are medication plans communicated between prescribers and pharmacists for patients. An ideal prescription must be rational, evidence-based, complete, and clear, and enhance the therapeutic outco…
Article
Investigation of a Gel Formulation Using a Halobetasol–Phospholipid Complex for Managing the Symptoms of Psoriasis
Kashish Wilson, Chander Parkash Dora, Garima, Bharat Bhushan, Anjali Bhardwaj, Pramila Chaubey, Sumeet Gupta
pp. 231–243 · DOI: 10.1177/0976500X251347400 · Published 2026
Background: Several therapies are available for psoriasis, including oral, parenteral, and phototherapy. However, these treatments present various drawbacks, like mucosal ulceration, stomatitis, bioavailability issues, p…
Article
A Nasal Gel Formulation of Ubrogepant Nanoparticles for Enhanced and Rapid Brain Delivery in the Treatment of Migraine
Vignesh Mohan, Anil Meghrajji Pethe
pp. 244–252 · DOI: 10.1177/0976500X251347402 · Published 2026
Background: Ubrogepant is a first-generation gepant-class drug approved for the oral treatment of migraine. Objectives: This work aimed at developing an intranasal gel consisting of ubrogepant nanoparticles (NPs), with t…
Article
Comparative Real-world Adverse Drug Reactions of Fluoxetine and Sertraline in Outpatients with Depression
Chompoonuch Werawattanachai, Pattaramart Hadee, Jitapa Sornsoongneon, Tuanthon Boonlue
pp. 253–259 · DOI: 10.1177/0976500X251390085 · Published 2026
Background: Selective serotonin reuptake inhibitors (SSRIs), including fluoxetine and sertraline, are widely prescribed for depression due to their favorable safety profiles compared to older anti-depressants. However, t…
Article
Multilevel Deep Learning Technique Based Classification of Lung Cancer as Per Tumor Node Metastasis Coding
Vanita Dnyandev Jadhav, Lalit Vasantrao Patil
pp. 260–270 · DOI: 10.1177/0976500X251353660 · Published 2026
Aim/Background: Accurate staging of lung cancer is critical for treatment planning and prognosis. Traditional methods typically rely on binary classification and manual analysis of computed tomography (CT) scans, limitin…
Article
Mapping the Scientific Landscape of Leopoldia comosa (L.) Miller Research: A Comprehensive Bibliometric and Thematic Analysis (1877–2024)
Abdullah Farasani
pp. 271–278 · DOI: 10.1177/0976500X251355425 · Published 2026
Background: Leopoldia comosa is a traditional Mediterranean plant with medicinal and nutritional value. Despite its long history of use, scientific exploration remains limited. Objectives: This study aimed to provide the…
Article
Development and Validation of a Risk Prediction Model for Intraoperative Hypothermia in Elderly Patients Undergoing Total Hip Replacement Surgery
Yu Hao Cui, JinYi Zhu
pp. 279–283 · DOI: 10.1177/0976500X251383596 · Published 2026
Background: Intraoperative hypothermia is a common complication in elderly patients undergoing joint replacement surgery that can lead to adverse outcomes. Objectives: This study aimed to analyze the pertinent risk facto…
Article
Impact of Pulmonary Rehabilitation on Qualityof-life Metrics in Patients with Chronic Respiratory Diseases: A Comparative Analysis of SF-36, SGRQ, and SOBQ Outcomes
Sneha Chacko, Gaurang Shah, Tushar Patel, Aviral R. Tripathi, Indermeet Singh Anand, Chirag Shah
pp. 284–291 · DOI: 10.1177/0976500X251350484 · Published 2026
Background: Chronic respiratory diseases (CRDs) significantly impact patients’ quality-of-life (QoL), necessitating effective interventions for symptom management and functional improvement. Pulmonary rehabilitation (PR)…
Article
Association of NAT2 341C/T Gene Polymorphism and Risk of Periodontitis in Smokers: A Case-control Study
Sangeetha Subramanian, Kavitha Sanjeev, Prakash PSG, Devapriya Appukuttan, Jasmine Crena, Santo Grace Umesh
pp. 292–298 · DOI: 10.1177/0976500X251355377 · Published 2026
Background: Periodontitis, an inflammatory disease, is caused by oral biofilm, and several risk factors propagate it. Smoking is a significant risk factor that increases the severity of the disease. Arylamine N-acetyltra…
Article
Understanding the Application of Selective Serotonin Reuptake Inhibitors (SSRIs) in the Management of Premature Ejaculation
Ahmed S. Alamer
pp. 299–307 · DOI: 10.1177/0976500X251357060 · Published 2026
Background: Premature ejaculation (PE) is one of the most common sexual dysfunctions affecting men. Among the available treatments, selective serotonin reuptake inhibitors (SSRIs) have gained considerable attention. Obje…

Case Report

Article
Drug-induced Acneiform Breakout in a Postpartum Psychosis Patient: A Case Report with Literature Review Deepalakshmi M1 , Sudharsan M2,3 , Rajalakshmi S4
Dharini Boopathi, Suganya P, Arunkumar Subramanian, Rajamohamed H
pp. 308–314 · DOI: 10.1177/0976500X251347404 · Published 2026
Background: Acneiform eruption is a dermatological condition resembling acne vulgaris, with a similar clinical presentation that is often difficult to differentiate. Several medications like corticosteroids, anti-convuls…