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    Article

    Content Determination and Anti-fatigue Effect of the Purified Anthocyanin from Purple Daucus carota

    Fang-Rong Cheng1, Yue-Yue Mao1, Song-Heng Jin2★, Rong-Rong Cai2★, Ke Yuan2★ Corresponding author

    1. 1College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, China.
    2. 2Jiyang College of Zhejiang Agriculture and Forestry University, Zhu’ji, P.R, China.

    CORRESPONDENCE

    Song-Heng Jin

    Jiyang College of Zhejiang Agriculture and Forestry University, Zhu’ji, P.R, China.

    shjin@zafu.edu.cn

    Received: 24-10-2019; Revised: 19-11-2019; Accepted: 21-04-2020.

    Volume 16, Issue 71 · pp. 670–674 · PUBLISHED 20 October 2020 · DOI: 10.4103/pm.pm_452_19

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant used in traditional medicine for bone healing. Objective: The present study was aimed to evaluate the anti-inflammatory and analgesic activities of the methanolic extract of <em>Cissus quadrangularis</em> (MECQ) in experimental animal models. Materials and Methods: The anti-inflammatory activity was evaluated using carrageenan-induced rat paw edema model, and analgesic activity was evaluated using acetic acid-induced writhing and tail-flick models in mice. Results: MECQ at doses of 200 and 400 mg/kg showed significant (P < 0.01) anti-inflammatory activity in carrageenan-induced rat paw edema. In analgesic models, MECQ showed significant (P < 0.01) reduction in the number of writhes in acetic acid-induced writhing model and increased the reaction time in tail-flick model. Conclusion: The results suggest that MECQ possesses significant anti-inflammatory and analgesic activities, which supports its traditional use.

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      Cheng, F., Mao, Y., Jin, S., Cai, R., & Yuan, K. (2020). Content Determination and Anti-fatigue Effect of the Purified Anthocyanin from Purple Daucus carota. Pharmacognosy Magazine, 16(71), 670–674. https://doi.org/10.4103/pm.pm_452_19