Volume 10, Issue 39

Direct proof by 13C‑nuclear magnetic resonance of semi‑purified extract and isolation of ent‑Catechin from leaves of Eucalyptus cinerea

Sayonara Mendes Silva, Simone Yae Abe, Fernanda Giacomini Bueno, Norberto Peporine Lopes, João Carlos Palazzo de Mello, Tomoe Nakashima

pp. 191–194 · DOI: 10.4103/0973-1296.137355 · Published 24 July 2014

Background: Eucalyptus cinerea F. Muell. ex Benth. is native to Australia and acclimatized to Southern Brazil. Its aromatic leaves are used for ornamental purposes and have great potential for essential oil production, a…

Simultaneous determination of four neuroprotective compounds of Tilia amurensis by high performance liquid chromatography coupled with diode array detector

Bohyung Lee, Jin Bae Weon, Bo‑Ra Yun, Jiwoo Lee, Min Rye Eom, Choong Je Ma

pp. 195–199 · DOI: 10.4103/0973-1296.137353 · Published 24 July 2014

Background: Tilia amurensis consists of various compounds, such as flavonoids and terpenoids. Objective: A simple and reliable high performance liquid chromatography (HPLC) coupled with the diode array detector (DAD) met…

Comparison of toad skins Bufo bufo gargarizans Cantor from different regions for their active constituents content and cytotoxic activity on lung carcinoma cell lines

Congyan Liu, Wei Cao, Yan Chen, Ding Qu, Jing Zhou

pp. 207–212 · DOI: 10.4103/0973-1296.137358 · Published 24 July 2014

Background: The skin of Bufo bufo gargarizans Cantor, rich in bufadienolides, peptides, and alkaloids, has approved pharmacological activity for preliminary anti‑liver and lung tumor treatment. However, few studies have …

New Sesquiterpene and Polymethoxy‑Flavonoids from Artemisia annua L

Yang Chu, Hongbo Wang, Jing Chen, Yue Hou

pp. 213–216 · DOI: 10.4103/0973-1296.137359 · Published 24 July 2014

Preparation and pharmacokinetics in beagle dogs of ganershu sustained‑release pellets

Jin-huo Pan, Jian-chun Wang, Zhi-tao Jiang, Ting Zhang, Shao-bo Ge, Ye-xia Zhang, Xin Jin, Guo-jun Yan

pp. 217–226 · DOI: 10.4103/0973-1296.137360 · Published 24 July 2014

Background: The active ingredients of Ganershu compound recipe, which are effective for hepatitis treatment in liver protection and transaminase reduction. However, the active ingredients of Ganershu compound recipe are …

Stability indicating studies on NMITLI 118RT+ (standardized extract of withania somnifera dunal)

Hafsa Ahmad, Kiran Khandelwal, Shakti Deep Pachauri, Rajender Singh Sanghwan, Anil Kumar Dwivedi

pp. 227–233 · DOI: 10.4103/0973-1296.137361 · Published 24 July 2014

Background: Withania somnifera Dunal (Ashwagandha) is an Indian medicinal plant of great medicinal value; used in many clinically proven conditions. NMITLI‑118RT+ is a candidate drug under a Council of Scientific and Ind…

Efficient production of flavonoids in Fagopyrum tataricum hairy root cultures with yeast polysaccharide elicitation and medium renewal process

Jiang‑Lin Zhao, Liang Zou, Cai‑Qiong Zhang, Yuan‑Yuan Li, Lian‑Xin Peng, Da‑Bing Xiang, Gang Zhao

pp. 234–240 · DOI: 10.4103/0973-1296.137362 · Published 24 July 2014

Background: Tartary buckwheat (Fagopyrum tataricum), an excellent edible and medicinal crop, has been widely used as a daily diet and traditional medicine for a long time. The major functional components of Fagopyrum tat…

LC‑MS/MS determination and pharmacokinetics study of puerarin and daidzein in rat plasma after oral administration of Gegenqinlian decoction and Radix Puerariae extract

Yifan Zhang, Jin Yuan, Ying Wang, Yue Wang, Rui An, Xinhong Wang

pp. 241–248 · DOI: 10.4103/0973-1296.137363 · Published 24 July 2014

Background: Gegenqinlian decoction (GQD) is a famous traditional medicine recipe. It is composed of four herbs including Radix Puerariae (GG), Radix Scutellariae (HQ), Rhizoma Coptidis (HL) and Radix Glycyrrhizae (GC), w…

Fast analysis of principal volatile compounds in crude and processed Atractylodes macrocephala by an automated static headspace gas chromatography‑mass spectrometry

Jida Zhang, Gang Cao, Yunhua Xia, Chengping Wen, Yongsheng Fan

pp. 249–253 · DOI: 10.4103/0973-1296.137364 · Published 24 July 2014

Objective: Atractylodes macrocephala, a famous herbal medicine, is used extensively in the practice of Traditional Chinese Medicine (TCM). Processing procedure is a common approach that usually occurs before A. macroceph…

Qualitative and quantitative analysis of the major constituents in traditional Chinese medicine Danmu injection using LC‑ESI‑MSn and LC‑DAD

Fen‑Xia Zhu, Jing‑Jing Wang, Xiu‑Feng Li, E Sun, Xiao‑Bin Jia

pp. 254–264 · DOI: 10.4103/0973-1296.137365 · Published 24 July 2014

Background: Danmu injection, a traditional Chinese medicine (TCM) preparation made from Nauclea officinalis, has been commonly used for the treatment of cold, fever, swelling of throat in China. However, the chemical con…

Rapid and undamaged analysis of crude and processed Radix Scrophulariae by Fourier transform infrared spectroscopy coupled with soft independent modeling of class analogy

Huiping Zhu, Gang Cao, Hao Cai, Baochang Cai, Jue Hu

pp. 265–270 · DOI: 10.4103/0973-1296.137366 · Published 24 July 2014

Objective: The main objective of this work is to determine the feasibility of identification of crude and processed Radix Scrophulariae using the Fourier transform infrared spectroscopy couple with soft independent model…

Antidepressant‑like effects of Chaihu‑Shugan‑San via SAPK/JNK signal transduction in rat models of depression

Yun‑Hui Li, Chun‑Hu Zhang, Juan Qiu, Su‑E Wang, Sui‑Yu Hu, Xi Huang, Ying Xie, Yang Wang

pp. 271–277 · DOI: 10.4103/0973-1296.137367 · Published 24 July 2014

Background: Chaihu‑Shugan‑San (CHSGS), a traditional Chinese medicinal herbal formula, registered in Jingyue Quanshu, has been indicated that oral administration of the extract from it can remit depressive disorder. C‑Ju…

Content determination of the flavonoids in the different parts and different species of Abelmoschus esculentus L. by reversed phase‑high performance liquid chromatograph and colorimetric method

Yin Lin, Min-feng Lu, Hai-bing Liao, Yu-xian Li, Wei Han, Ke Yuan

pp. 278–284 · DOI: 10.4103/0973-1296.137368 · Published 24 July 2014

Background: This research will establish the ultraviolet colorimetric method to determine the total flavonoid content in different species and different parts of Abelmoschus esculentus L. Materials and Methods: We establ…

Pharmacokinetics and tissue distribution study of tanshinone IIA after oral administration of Bushen Huoxue Qubi granules to rats with blood stasis syndrome

Yuanqing Wang, Jianye Yan, Shunxiang Li, Xiong Cai, Wei Wang, Kun Luo, Dan Huang, Jiesheng Gao

pp. 285–291 · DOI: 10.4103/0973-1296.137369 · Published 24 July 2014

Background: Bushen Huoxue Qubi (BHQ) granules, a traditional Chinese medicine preparation, has been clinically used for the treatment of the blood stasis syndrome. Objective: The main objective is to investigate whether …

Optimization of simultaneous ultrasonic‑assisted extraction of water‑soluble and fat‑soluble characteristic constituents from Forsythiae Fructus Using response surface methodology and high‑performance liquid chromatography

Yong‑Gang Xia, Bing‑You Yang, Jun Liang, Di Wang, Qi Yang, Hai‑Xue Kuang

pp. 292–303 · DOI: 10.4103/0973-1296.137370 · Published 24 July 2014

Background: The compounds (+)‑pinoresinol‑β‑glucoside (1) forsythiaside, (2) phillyrin (3) and phillygenin (4) were elucidated to be the characteristic constituents for quality control of Forsythiae Fructus extract by ch…

Analysis of the influence of sulfur‑fumigation on the volatile components of Angelicae sinensis Radix by comprehensive two‑dimensional gas chromatography/ time‑of‑flight mass spectrometry

Gang Cao, Hao Cai, Yajing Lou, Sicong Tu, Xiao Liu, Kunming Qin, Baochang Cai

pp. 304–313 · DOI: 10.4103/0973-1296.137371 · Published 24 July 2014

Background: Sulfur‑fumigation of Angelicae sinensis Radix causes changes in the structure and composition of volatile components. These changes alter the curative effect and the quality of A. sinensis Radix. Materials an…

Antitumor effects of dammarane‑type saponins from steamed Notoginseng

Fan He, Yan Ding, Chun Liang, Seok Bean Song, De‑Qiang Dou, Gyu Yong Song, Young Ho Kim

pp. 314–317 · DOI: 10.4103/0973-1296.137372 · Published 24 July 2014

Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells

Yang Bai, Xiao‑Yuan Qu, Jun‑Qiang Yin, Liangcai Wu, Hong Jiang, Han‑Wu Long, Qiang Jia

pp. 318–324 · DOI: 10.4103/0973-1296.137373 · Published 24 July 2014

Background: Methyl protodioscin (MPD) is a furostanol bisglycoside with antitumor properties. It has been shown to reduce proliferation, cause cell cycle arrest. Objective: The present study elucidates the mechanism unde…

Induction of apoptosis by Cordyceps militaris fraction in human chronic myeloid leukemia K562 cells involved with mitochondrial dysfunction

Tian Tian, Liyan Song, Qin Zheng, Xianjing Hu, Rongmin Yu

pp. 325–331 · DOI: 10.4103/0973-1296.137374 · Published 24 July 2014

Background: Cordyceps militaris is widely used for various ethno medical conditions including cancer and inflammation complications in traditional Chinese medicine. Objective: To investigate the in vitro antitumor activi…

Enhanced dissolution and stability of Tanshinone IIA base by solid dispersion system with nano‑hydroxyapatite

Yan‑rong Jiang, Zhen‑hai Zhang, Sai‑yan Huang, Yan Lu, Tian‑tian Ma, Xiao‑bin Jia

pp. 332–337 · DOI: 10.4103/0973-1296.137375 · Published 24 July 2014

Background: Tanshinone IIA (TSIIA) exhibits a variety of cardiovascular effects; however, it has low solubility in water. The preparation of poorly soluble drugs for oral delivery is one of the greatest challenges in the…

Novel characterization of Radix Angelicae Dahuricae before and after the sulfur‑fumigation process by combining high performance liquid chromatographic fingerprint and multi‑ingredients determination

Xiao Liu, Jingjing Liu, Hao Cai, Songlin Li, Xiaoqing Ma, Yajing Lou, Kunming Qin, Hongyue Guan, Baochang Cai

pp. 338–345 · DOI: 10.4103/0973-1296.137376 · Published 24 July 2014

Background: Harmful sulfur‑fumigation processing method is abused during Radix Angelicae Dahuricae preparation. However, the analytical technique characterizing Radix Angelicae Dahuricae before and after the sulfur‑fumig…

Phytochemical compositions of volatile oil from Blumea balsamifera and their biological activities

Zhi‑long Jiang, Yan Zhou, Wei‑chen Ge, Ke Yuan

pp. 346–352 · DOI: 10.4103/0973-1296.137377 · Published 24 July 2014

Background: This research, extract compositions of volatile oil in Blumea balsamifera (Linn.) DC by steam distillation method. The gas chromatograph‑mass spectrometer technology (GC‑MS) was used to separate and determine…

A rapid identification of four medicinal chrysanthemum varieties with near infrared spectroscopy

Bangxing Han, Hui Yan, Cunwu Chen, Houjun Yao, Jun Dai, Naifu Chen

pp. 353–358 · DOI: 10.4103/0973-1296.137378 · Published 24 July 2014

Background: For genuine medicinal material in Chinese herbs; the efficient, rapid, and precise identification is the focus and difficulty in the filed studying Chinese herbal medicines. Chrysanthemum morifolium as herbs …

Simultaneous determination of esculetin, quercetin‑3‑O‑β‑D‑glucuronide, quercetin‑3‑O‑β ‑D-glucuronopyranside methyl ester and quercetin in effective part of Polygonum Perfoliatum L. using high performace liquid chromatography

Dongsheng Fan, Yang Zhao, Xin Zhou, Xiaojian Gong, Chao Zhao

pp. 359–366 · DOI: 10.4103/0973-1296.137379 · Published 24 July 2014

Objective: In the present study, a high performance liquid chromatography (HPLC) coupled with photodiode array detection was developed for simultaneous quantitation of esculetin, quercetin‑3‑O‑b‑D‑glucuronide, quercetin‑…

In vivo anti‑fatigue activity of sufu with fortification of isoflavones

Yunxian Liu, Yun Zhou, Satoru Nirasawa, Eizo Tatsumi, Yongqiang Cheng, Lite Li

pp. 367–373 · DOI: 10.4103/0973-1296.137380 · Published 24 July 2014

Background: Sufu is a traditional Chinese fermented soybean food. Isoflavones are abundant in soybean and products incorporated with isoflavones exert many health benefits. The aim of this study was to investigate anti‑f…

Development and validation of an UPLC‑ESI‑MS/ MS method for determination of dehydroevodiamine, limonin, evodiamine, and rutaecarpine in Evodiae Fructus

Yang Zhao, Yunling Zhao, Xin Zhou, Xiaojian Gong

pp. 374–383 · DOI: 10.4103/0973-1296.137381 · Published 24 July 2014

Objective: Evodiae Fructus (EF), one of the most widely used traditional Chinese medicines, mainly consists of alkaloids, is widely used for the treatments of headache and gastrointestinal disorders. In this study, a sen…

Anticancer activity of cissampelos pareira against dalton’s lymphoma ascites bearing mice

B. Samuel Thavamani, Molly Mathew, S. P. Dhanabal

pp. 200–206 · DOI: 10.4103/0973-1296.137356 · Published 24 July 2014

Background: Cissampelos pareira (Menispermaceae) is used in folk Indian system of alternative medicine, for its analgesic, antipyretic, diuretic, antilithic, and emmenagogue properties. Objective: To evaluate Cissampelos…