Biological activity of Crambe orientalis L. growing in Iran
S. M. Razavi1★, G. Zarrini2, S. Zahri1, K. Ghasemi1, S. Mohammadi1★ Corresponding author
- 1Department of Biology, University of Mohaghegh Ardabili, Ardabil, Iran.
- 2Depatrment of Animal Sciences, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran
Received: 10-03-2009; Accepted: 09-04-2009.
Volume 1, Issue 3 · pp. 125–129 · PUBLISHED May-Jun 2009 · DOI:
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ABSTRACT
Crambe orientalis (Brassicaceae) is a perennial herb growing wild in Iran. Cytotoxic, antioxidant, antimicrobial and phytotoxic effects of the plant leaves extracts have been evaluated by MTT, DPPH, Disc diffusion and lettuce assays, respectively. Our results showed that dichloromethane and methanol extracts of the plant leaves exhibited high cytotoxic effects against Mc-Coy cell line with IC50 value of 659 and 432 µg/ml, respectively. The extracts indicated high antioxidant activity with RC50 value of 33.3 and 40.5 µg/ml, respectively. Methanol extract showed strong antibacterial activity against both gram-positive and gram-negative bacteria. All the extracts displayed significant allelopatic potential, as well as. It is assumed that biological activity of the plant may be related to presence of isothiocyanates in the plant leaves.
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Razavi, S. M., Zarrini, G., Zahri, S., Ghasemi, K., & Mohammadi, S. (2009). Biological activity of Crambe orientalis L. growing in Iran. Pharmacognosy Research, 1(3), 125–129.