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    GC-MS Analysis of Bio-Active Compounds in Hydroethanolic Extract of Caesalpinia sappan

    Rangenahalli Chidananada Murthy Pooja1, Doddla Raghunathanaidu Bharathi1 Corresponding author

    1. 1Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, BG. Nagar, Karnataka, INDIA.

    CORRESPONDENCE

    Doddla Raghunathanaidu Bharathi

    Dr. Bharathi Doddla Raghunathanaidu, Dean of Pharmacy, Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, BG. Nagar, Karnataka, INDIA.

    rambha.eesh@gmail.com

    ORCID: 0000-0003-2625-3711

    Received: 22-02-2024; Revised: 20-03-3; Accepted: 04-04-2024.

    Volume 17, Issue 1 · pp. 307–312 · PUBLISHED 2025 · DOI: 10.5530/pres.20251348

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Background The presence of phytochemical constituents has been reported from species of the Compositae Caesalpiniaceae. Objectives The present study was designed to determine the bioactive compounds in the heartwood of hydroethanolic extract. Materials and Methods Phytochemical screening of the entire herb of Caesalpinia sappan revealed the presence of some bioactive components. Gas Chromatography-Mass Spectrometry (GC-MS) analysis of the heartwood of hydroethanolic extract was performed on GC-MS equipment. Results The phytochemical tests showed the presence of alkaloids, alkaloids, cardiac glycosides, flavonoids, phenols, phlorotannins, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, protein/amino acids in the hydroethanolic extract of Caesalpinia sappan. The GC-MS analysis has shown the presence of different phytochemical compounds in the hydroethanolic extract of Caesalpinia sappan. A total of 38 compounds were identified. The major components are 9-octadecenoic acid, Oleic Acid, Sarcosine and Dinonanoin. Conclusion From the results, it is evident that Caesalpinia sappan contains various photo components and is recommended as a plant of phytopharmaceutical importance.

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      Pooja, R. C. M., & Bharathi, D. R. (2025). GC-MS Analysis of Bio-Active Compounds in Hydroethanolic Extract of Caesalpinia sappan. Pharmacognosy Research, 17(1), 307–312. https://doi.org/10.5530/pres.20251348