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    Comparative assessment on in vitro antioxidant activities of ethanol extracts of Averrhoa bilimbi, Gymnema sylvestre and Capsicum frutescens

    Md. Mominur Rahman1, Md. Razibul Habib2, Md. Anayet Hasan3, Mohammad Al Amin3, Ayan Saha3, Adnan Mannan3★★ Corresponding author

    1. 1Department of Pharmacy, International Islamic University Chittagong, Chittagong, Bangladesh
    2. 2Superintendent of Drugs, Directorate General of Drug Administration, Dhaka
    3. 3Department of Genetic Engineering and Biotechnology, Faculty of Biological Sciences, University of Chittagong, Chittagong-4331, Bangladesh

    CORRESPONDENCE

    Adnan Mannan

    *Address for correspondence: Dr. Adnan Mannan, Department of Genetic Engineering and Biotechnology, Faculty of Biological Sciences, University of Chittagong, Chittagong - 4331, Bangladesh.

    adnan.mannan@cu.ac.bd

    Revised: 21-07-2013.

    Volume 6, Issue 1 · pp. 36–41 · PUBLISHED January-March 2014 · DOI: 10.4103/0974-8490.122915

    View on Pharmacogn. Res. original site ↗

    ABSTRACT

    Background Averrhoa bilimbi, Gymnema sylvestre and Capsicum frutescens are medicinal plants commonly used as traditional medicine for the treatment of various diseases. The present study was designed to investigate the antioxidant activities of Ethanolic extract of A. bilimbi, G. sylvestre and C. frutescens. Materials and Methods The antioxidant activity of the extracts were evaluated using total phenolic and flavonoid contents, ferric reducing power and the free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH). Results Total phenolic and flavonoid contents were higher in G. sylvestre (53.63636 ± 0.454545 mg/g gallic acid equivalent) and C. frutescens (26.66667 ± 2.081666 mg/g quercetin equivalent) respectively. Reducing power of the crude ethanol extracts increased with the concentrations of the extracts and all the extracts showed moderate free radical scavenging activity against DPPH. The plant extract displayed moderate phenolic and flavonoid contents compared to gallic acid and quercetin equivalent respectively, whereas also exhibited significant scavenging of DPPH radical and reducing power compared with ascorbic acid as standard. Conclusion Our study suggests that G. sylvestre has significant antioxidant activity. The antioxidant compound of this plant might be a therapeutic candidate against oxidative stress related diseases. Different sub-fraction of A. bilimbi and C. frutescens should be studied further to assess the effect. Further study is necessary for isolation and characterization of the active antioxidant agents for better treatment.

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      Rahman, M. M., Habib, M. R., Hasan, M. A., Amin, M. A., Saha, A., & Mannan, A. (2014). Comparative assessment on in vitro antioxidant activities of ethanol extracts of Averrhoa bilimbi, Gymnema sylvestre and Capsicum frutescens. Pharmacognosy Research, 6(1), 36–41. https://doi.org/10.4103/0974-8490.122915