Volume 13, Issue 1

2022 · pp. 5–107 · 16 articles

Volume: 13
Issue: 1
Published: 2022
Pages: 5–107
Articles: 16
Sections: 4
ISSN: ISSN: Print - 0976-500X, Online - 0976-5018
Journal: J Pharmacol. Pharmacother.

Review Article Case Report Research Article Research Letter

In this issue

Review Article

Review
Antivitamins: A Silver Lining in the Era of Antimicrobial Resistance
Nayesha Mahwish, Laxminarayana Kurady Bairy, Sureshkumar Srinivasamurthy
pp. 5–13 · DOI: 10.1177/0976500X221080378 · Published 2022
Antivitamins are compounds that negate the biological effects of vitamins. They have been successfully exploited for the development of various classes of drugs. In the early 19th century, the antifolate prontosil was de…

Case Report

Article
Xylometazoline Induced Isolated Left Medial Cerebellar Peduncle Infarct: A Rare Case Report
Ankit Bhardwaj, Shoma Mukherjee, Vandana Roy
pp. 102–107 · DOI: 10.1177/0976500X221080224 · Published 2022
Xylometazoline, a sympathomimetic available as over the counter drug, acts as a nasal decongestant and has been reported as an independent risk factor for hemorrhagic and ischemic stroke. The chronic use of xylometazolin…
Article
Bullous Drug Reaction with Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
K. Geetha, Puja Puja
pp. 99–101 · DOI: 10.1177/0976500X221080309 · Published 2022
Hypoglycemic drugs in the dipeptidyl peptidase-4 (DPP-4) inhibitor class are used as a second-line treatment for type 2 diabetes mellitus. With DPP-4 inhibitors, there have been a few reports of cutaneous side effects su…

Research Article

Article
Systematic Review and Meta-Analysis Comparing the Safety of Natalizumab, Ocrelizumab, and Alemtuzumab in Treating Relapsing–Remitting, Primary Progressive, and Secondary Progressive Multiple Sclerosis
Pooja Raina, Somnath Basu, Ramesh K Goyal, Pravat K Sahoo, Rajani Mathur
pp. 14–23 · DOI: 10.1177/0976500X221080225 · Published 2022
Three monoclonal antibodies—natalizumab (NTZ), ocrelizumab (OCR), and alemtuzumab (ALM)—are the mainstays for the treatment of both relapsing and progressive forms of multiple sclerosis (MS). Here, their safety in patien…
Article
Review of the Long-Term Effect of the Atypical Antipsychotic Medication on the Bone Mineral Density of the Pediatric Patient with Consideration of Autism Spectrum Disorder
Wisam Al Jumaili, Ashraf Muzwagi
pp. 24–30 · DOI: 10.1177/0976500X221080296 · Published 2022
Objectives: To shed some light on the understudied complication of chronic prolonged exposure to antipsychotics (AP) in children with consideration to with autism spectrum disorder (ASD). Methods: We electronically searc…
Article
The Role of Olfactory System in the Etiogenesis of Parkinson’s Diseases: An Overview
Jiju Narayanan Avanipully, Dithu Thekkekkara, Sahyadri M, Vipan K. Parihar, Santhepete Nanjundaiah Manjula
pp. 31–39 · DOI: 10.1177/0976500X221085802 · Published 2022
Parkinson’s disease (PD) mainly affects the dopaminergic neuronal networks of the substantia nigra, which leads to both motor and nonmotor symptoms of the disease. Based on the reports from the previous studies, 95% of t…
Article
COVID-19 and Substance Use: A Scientometric Assessment of Global Publications During 2020 and 2021
Sandeep Grover, B.M. Gupta, K.K. Mueen Ahmed
pp. 40–47 · DOI: 10.1177/0976500X221080393 · Published 2022
Aim: This study aimed to assess the characteristics and trends of research on substance use and COVID-19. Methods: Keywords related to “Covid-19” and “Substance Use” were used in a search query formulated for the Scopus …
Article
Ethnopharmacology Research: A Scientometric Assessment of Indian Publications During 2011 to 2020
Chaman Sab M., Mallikarjun Kappi, K.K. Mueen Ahmed
pp. 48–58 · DOI: 10.1177/0976500X221082839 · Published 2022
The current research has been conducted to study the ethnopharmacology research output in the past 10 years (2011–2020) after using Web of Science (WoS) database. The present study has used WoS database to collect the et…
Article
Comparison Between Dexamethasone and Fentanyl as an Adjuvant to Bupivacaine and Lignocaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgery
Shilpa Sarang Kore, Smita Bhau Ubhe, Fathima Fasil
pp. 59–65 · DOI: 10.1177/0976500X221085803 · Published 2022
Objective: To compare the effects of dexamethasone and fentanyl when added to a mixture of bupivacaine and lignocaine in supraclavicular blocks in patients undergoing forearm surgeries. Methods: Sixty-six patients aged b…
Article
Predictors of Pharmacotherapy and Quality of Life Among Patients With Diabetic Foot Syndrome: A Cross-Sectional Study from a Tertiary Care Hospital in India
E. Pasangha, B. George, K. B. Bhuvana, D. Padmini
pp. 66–71 · DOI: 10.1177/0976500X221080291 · Published 2022
Objective: To assess the patterns and predictors of pharmacotherapy and QOL in DFS patients in an Indian tertiary care hospital. Methods: A cross-sectional study was conducted among inpatients with DFS. Data on sociodemo…
Article
Development of Physiologically Based Pharmacokinetic Model and Assessment of the Impact of Renal Underdevelopment in Preterm Infants on the Pharmacokinetics of Aminophylline
Hari Prabhath Tummala, Rachana Balusu, Sahithi Thotakura, Achyuth Kumar Pasnoor, Arun Prasath Raju, Shivakumar Mahadeva Lal, Leslie Edwards Lewis, Surulivelrajan Mallayasamy
pp. 72–78 · DOI: 10.1177/0976500X221080209 · Published 2022
Objective: To develop a physiologically based pharmacokinetic (PBPK) model for individualization of the dosing regimen considering the physiological requirements of these preterm neonates. Methods: The study comprised pr…
Article
A Randomized Double-Blind Comparative Study of Efficacy and Safety Between Low-Dose Etoricoxib and Ibuprofen Coadministered with Low-Dose Paracetamol for Dental Pain
Kothari Saroj, Bansal Haresh, Paharia Yogendra
pp. 79–84 · DOI: 10.1177/0976500X221080380 · Published 2022
Objective: To study the safety and efficacy of low-dose etoricoxib and low-dose paracetamol versus ibuprofen and low-dose paracetamol treatments in patients who experienced acute pain after tooth extraction. Methods: A t…
Article
Study of Hemodynamic Effects of Preoperative Single-Bolus Dexmedetomidine in Elective Laparoscopic Surgeries
Fathima Fasil, Girish Saundattikar, Reema Hemant Jawale, Naveen Kumar J.
pp. 85–91 · DOI: 10.1177/0976500X221080390 · Published 2022
Objective: To observe the hemodynamic effects of a single bolus dose of dexmedetomidine in patients undergoing elective laparoscopic surgeries. Methods: A total of 60 adult patients were randomized into two groups of 30 …

Research Letter

Article
Availability of the Essential Medicines is Community Pharmacies: A Cross-Sectional Study
Pallavi Jha, Sneha Ambwani, Surjit Singh, Pankaj Bhardwaj, Shobhan Babu Varthya, Jaykaran Charan
pp. 92–94 · DOI: 10.1177/0976500X221080370 · Published 2022
World Health Organization (WHO) defines essential drugs or medicines as “those drugs that satisfy the healthcare needs of majority of the population; they should therefore be available at all times in adequate amounts an…
Article
Can We Use Terminalia Arjuna (Roxb.) Wight and Arn in Place of Novel Oral Anticoagulants (NOACs) in Post-COVID-19 Cardiac Conditions?
Shridhar Dwivedi, Vinod Sharma, C. R. Patil
pp. 95–96 · DOI: 10.1177/0976500X221080202 · Published 2022
COVID-19 is known to cause several cardiac disorders such as pancarditis, coronary artery disease (CAD), arrhythmias, cardiomyopathy, and stroke during and after the active stage of the COVID-19 infection, even when the …
Article
Physician Preferences for Olanzapine Standard Oral Tablets and Orally Disintegrating Tablets: A Cross-Sectional Survey
Hardik Gandhi
pp. 97–98 · DOI: 10.1177/0976500X221080392 · Published 2022
Olanzapine, a second-generation antipsychotic, is indicated for the treatment of schizophrenia and bipolar disorder.1 Oral formulations of olanzapine include standard oral tablets (SOT) and orally disintegrating tablets …