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    Identification and Quantification Bioactive Compounds on Liquid Extract of Capsicum chinense Jacq. Biquinho variety: Standardization and Quality Control is Frontier to Acceptance of Herbal Products on Market

    Lucélia de Sousa Brito1★, Aline Neves Pereira1, Emannuel Ítalo Alves Campos1, Andressa Tuane Santana Paz1, Mariana Cristina de Morais1, Leonardo Luiz Borges2,3, Edemilson Cardoso da Conceição1★ Corresponding author

    1. 1Bioproducts Research, Development and Innovation Department, Faculty of Pharmacy, Federal University of Goiás, Goiânia, Brazil.
    2. 2School of Medical, Pharmaceutical and Biomedical Sciences, Pontifical Catholic University of Goiás, 74605-010 Goiânia, Goiás, Brazil.
    3. 3Campus of Exact Sciences and Technologies, Campus Henrique Santillo, State University of Goiás Anápolis, Goiás 75001-970, Brazil.

    CORRESPONDENCE

    Lucélia de Sousa Brito

    Bioproducts Research, Development and Innovation Department, Faculty of Pharmacy, Federal University of Goiás, Goiânia, Brazil.

    luceliacos@gmail.com

    Received: 22-07-2019; Revised: 04-09-2019; Accepted: 01-10-2019.

    Volume 16, Issue 69 · pp. 288–293 · PUBLISHED 15 June 2020 · DOI: 10.4103/pm.pm_303_19

    View on Pharmacogn. Mag. original site ↗

    ABSTRACT

    Objectives: The aim of the present study was to develop and characterize the liquid extract of Capsicum chinense Jacq. Biquinho variety standardized in capsanthin. Materials and Methods: The liquid extract of the pepper was obtained by percolation and characterized about the solids content, pH, density and viscosity. Subsequently, the total carotenoids were determined by spectrophotometry in the pepper liquid extract, and an analytical method by high performance liquid chromatography was validated to quantify the capsanthin in the same sample. Results: The extract showed the following physicochemical properties: 19.16% ±1.03% (w/w) to solids content, a pH of 3.7 ± 0.06, density of 1.040 ± 0.0014 g/mL, and a viscosity of 3.22 mPas. The concentration of total carotenoids was 84.403 mg expressed as β‑carotene/100 g of the extract. Conclusion: The analytical method developed was considered simple, fast, selective, linear (in the range of 0.48 to 7.2 μg/mL for the liquid extract), precise, exact, and robust, and the found content of capsanthin was 1.13%. The analytical method used for the quantification of capsanthin was validated, proving the simplicity and speed of analysis of the evaluated sample.

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      Brito, L. D. S., Pereira, A. N., Campos, E. Í. A., Paz, A. T. S., Morais, M. C. D., Borges, L. L., & Conceição, E. C. D. (2020). Identification and Quantification Bioactive Compounds on Liquid Extract of Capsicum chinense Jacq. Biquinho variety: Standardization and Quality Control is Frontier to Acceptance of Herbal Products on Market. Pharmacognosy Magazine, 16(69), 288–293. https://doi.org/10.4103/pm.pm_303_19