Volume 10, Issue 37

Original Article

1. Article

   Crude ethyl acetate extract of marine microalga, Chaetoceros calcitrans, induces Apoptosis in MDA-MB-231 breast cancer cells

   Su Hua Goh, Noorjahan Banu Mohamed Alitheen, Fatimah Md Yusoff, Swee Keong Yap, Su Peng Loh

   pp. 1–8 · DOI: 10.4103/0973-1296.126650 · Published 7 February 2014

   Background: Marine brown diatom Chaetoceros calcitrans and green microalga Nannochloropsis oculata are benefi cial materials for various applications in the food, nutraceutical, pharmaceutical and cosmeceutical industries…

2. Article

   Effect of various absorption enhancers based on tight junctions on the intestinal absorption of forsythoside A in Shuang-Huang-Lian, application to its antivirus activity

   Wei Zhou, Xuan Xuan Zhu, Ai Ling Yin, Bao Chang Cai, Hai Dan Wang, Liuqing Di, Jin Jun Shan

   pp. 9–17 · DOI: 10.4103/0973-1296.126651 · Published 7 February 2014

   Background: Forsythoside A (FTA), one of the main active ingredients in Shuang-Huang-Lian (SHL), possesses strong antibacterial, antioxidant and antiviral effects, and its pharmacological effects was higher than that of …

3. Article

   Compounds isolated from Ageratum houstonianum inhibit the activity of matrix metalloproteinases (MMP-2 and MMP-9): An oncoinformatics study

   Anupriya Verma, Syed Mohd. Danish Rizvi, Sibhghatulla Shaikh, Mohd. Afaque Ansari, Shazi Shakil, Fauzia Ghazal, Mohd. Haris Siddiqui, Mohd. Haneef, Ajijur Rehman

   pp. 18–26 · DOI: 10.4103/0973-1296.126653 · Published 7 February 2014

   Background: In osteosarcoma tissue, both MMP-2 and MMP-9 are over expressed compared to their expression in non-affected stromal tissue. Hence, gelatinases are attractive targets for anti-osteosarcoma drugs. Objective: T…

4. Article

   Heartwood extract of Acacia catechu induces apoptosis in human breast carcinoma by altering bax/bcl-2 ratio

   Nikhil Baban Ghate, Bibhabasu Hazra, Rhitajit Sarkar, Nripendranath Mandal

   pp. 27–33 · DOI: 10.4103/0973-1296.126654 · Published 7 February 2014

   Background: The heartwood extract of A. catechu, called pale catechu or “Katha” in Hindi has been widely used in traditional Indian medicinal system. Although various pharmacological properties of this plant had been rep…

5. Article

   High-performance liquid chromatography determination and pharmacokinetics of coumarin compounds after oral administration of Samul-Tang to rats

   Youn-Hwan Hwang, Won-Kyung Cho, Doorye Jang, Jeong-Ho Ha, Jin Yeul Ma

   pp. 34–39 · DOI: 10.4103/0973-1296.126656 · Published 7 February 2014

   Background: Samul-tang has been traditionally used for the treatment of cardiovascular, gynecologic, cutaneous, and chronic infl ammation disorders. Although coumarin compounds do have various pharmacological activities a…

6. Article

   Aliphatic and eudesmalolide esters extracted from the roots of Inula racemosa Hook

   Maria Khan, S.R. Mir, Abuzar Ali, Mohammad Yusuf, Mohammed Ali

   pp. 40–46 · DOI: 10.4103/0973-1296.126657 · Published 7 February 2014

   Background: Phytochemical investigation of hydroalcoholic extract of the root of Inula racemosa Hook. Materials and Methods: Open silica gel column chromatographic techniques with different solvent systems was used for i…

7. Article

   Role of different types of potassium channels in the relaxation of corpus cavernosum induced by resveratrol

   Selvinaz Dalaklioglu, G. Ozbey

   pp. 47–52 · DOI: 10.4103/0973-1296.126658 · Published 7 February 2014

   Background: Resveratrol (RVT), one of the most commonly employed dietary polyphenol, is used in traditional Japanese and Chinese medicine for treatment of cardiovascular diseases. Recently, we have shown that RVT has a p…

8. Article

   Fatty acid composition and preclinical resarches on Anthemis wiedemanniana Fisch. & Mey.: Discovery of a new anti-infl ammatory agent

   Tuba Mert Gönenç, Esra Küpeli Akkol, Ipek Süntar, Tuğçe Fafal Erdoğan, Bijen Kıvçak

   pp. 53–60 · DOI: 10.4103/0973-1296.126660 · Published 7 February 2014

   Background: Anthemis species have been used for the treatment of gastrointestinal disorders, hemorrhoid, stomachache and infl ammatory diseases in Turkish folk medicine. Anthemis wiedemanniana Fisch. And Mey. is an endemi…

9. Article

   Curcumin attenuates neurotoxicity induced by fl uoride: An in vivo evidence

   Chhavi Sharma, Pooja Suhalka, Piyu Sukhwal, Neha Jaiswal, Maheep Bhatnagar

   pp. 61–65 · DOI: 10.4103/0973-1296.126663 · Published 7 February 2014

   Background: Curcumin (Cur), an active ingredient of turmeric is known to have multiple activities, including an antioxidant property and has been suggested to be useful in treatment of several neurological diseases. Obje…

10. Article

    Fraction and chemical analysis of antioxidant active polysaccharide isolated from fl ue-cured tobacco leaves

    Chunping Xu, Chenchen Yang, Duobin Mao

    pp. 66–69 · DOI: 10.4103/0973-1296.126664 · Published 7 February 2014

    Background: The metabolic compounds from tobacco were investigated to posses various biological activities, such as antioxidant, antimicrobial and neuroprotective activities. Materials and Methods: Polysaccharides were i…

11. Article

    Cytotoxic activity of Alpinia murdochii Ridl.: A mountain ginger species from Peninsular Malaysia

    Kae Shin Sim, Halijah Ibrahim, Sri Nurestri Abdul Malek, Devi Rosmy Syamsir, Khalijah Awang

    pp. 70–72 · DOI: 10.4103/0973-1296.126666 · Published 7 February 2014

    Background: Alpinia murdochii (Zingiberaceae) is a wild ginger species restricted to mountain areas of Peninsular Malaysia. Due to rapid development and deforestation activities, this species is becoming rare. This is th…

12. Article

    Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans Hance

    Chao Wang, Jinfu Wan, Zhinan Mei, Xinzhou Yang

    pp. 73–76 · DOI: 10.4103/0973-1296.126669 · Published 7 February 2014

    Background: Zanthoxylum simullans Hance is a popular natural spice belonging to the Rutaceae family and it is one of the common prescribed herbs in traditional Chinese medicine. Materials and Methods: The chemical consti…

13. Article

    Optimal inductive and cultural conditions of Polygonum multifl orum transgenic hairy roots mediated with Agrobacterium rhizogenes R1601 and an analysis of their anthraquinone constituents

    Bing Huang, Huanjie Lin, Chuanyan Yan, Hongyan Qiu, Lipeng Qiu, Rongmin Yu

    pp. 77–82 · DOI: 10.4103/0973-1296.126671 · Published 7 February 2014

    Background: Polygonum multiflorum is an important medicinal plant. Hairy roots systems obtained by transforming plant tissues with the natural genetic engineer Agrobacterium rhizogenes can produce valuable biological acti…

14. Article

    A validated high performance liquid chromatograph-photodiode array method for simultaneous determination of 10 bioactive components in compound hongdoushan capsule

    Liancai Zhu, Xian Yang, Jun Tan, Bochu Wang, Xue Zhang

    pp. 83–88 · DOI: 10.4103/0973-1296.126673 · Published 7 February 2014

    Background: The compound Hongdoushan capsule (CHC) is widely known as compound herbal preparation and is often used to treat ovarian cancer and breast cancer, and to enhance the body immunity, etc., in clinical practice.…