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    Phcog.Net PHARMACOGNOSY RESEARCH Volume 11 · Issue 1 · pp. 1–101
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    Cover: Pharmacognosy Research

    Pharmacognosy Research

    Volume 11, Issue 1

    · pp. 1–101 · 17 articles

    Volume
    11
    Issue
    1
    Published
    Pages
    1–101
    Articles
    17
    Sections
    2
    ISSN
    ISSN: Print - 0976-4836, Online - 0974-8490
    Journal
    Pharmacogn. Res.
    Original ArticleSHORT COMMUNICATION

    In this issue

    Original Article

    1. Article

      Chemical Characterization and Evaluation of Antioxidant and Antimicrobial Activities of Litchi chinensis Sonn

      Marisa De Oliveira Lopes, Ana Flávia Da Silva, Cláudio Daniel Cerdeira, Ingridy Simone Ribeiro, Isael Aparecido Rosa, Luis Felipe Cunha Dos Reis, Marcelo Aparecido Da Silva, Marcos José Marques, Jorge Kleber Chavasco, Geraldo Alves Da Silva

      pp. 1–7 · DOI: 10.4103/pr.pr_105_18 · Published

      Background: Litchi chinensis is used in traditional Chinese medicine and by Indian medical system. Ethnopharmacological studies show anti‑inflammatory, antidiabetic and analgesic activities, among others. However, there …

    2. Article

      Screening and Validating of 1, 1‑Diphenyl‑2‑Trinitrophenylhydrazine Scavengers from Danshen‑Honghua Herbal Pair

      Ya‑Li Wang, Shi‑Jun Yin, Sheng‑Li Huang, Qian Zhang, Hua Chen, Feng‑Qing Yang

      pp. 14–19 · DOI: 10.4103/pr.pr_94_18 · Published

      Background: Salvia miltiorrhiza (Danshen [DS]) and Carthamus tinctorius (Honghua [HH]) are commonly used traditional Chinese medicines for activating blood and removing stasis, and they were usually used as DS‑HH (Danshe…

    3. Article

      Mitochondrial Nephrotoxicity induced by Tacrolimus (FK‑506) and Modulatory Effects of Bacopa monnieri (Farafakh) of Tabuk Region

      Atif Abdulwahab A Oyouni, Shalini Saggu, Ehab Tousson, Anand Mohan, Abdullah Farasani

      pp. 20–24 · DOI: 10.4103/pr.pr_100_18 · Published

      Background: Tacrolimus is a known immunosuppressive drug used widely for organ transplantation, but its nephrotoxicity mechanism is still unclear. Objectives: The present study investigates the protective efficacy of Bac…

    4. Article

      Efficacy of Salivary and Diastase Extracts of Piper betle in Modulating the Cellular Stress in Placental Trophoblast during Preeclampsia

      Padmini Ekambaram, Chithra Balan

      pp. 25–30 · DOI: 10.4103/pr.pr_112_18 · Published

      Background:Betle leaf (BL) is an ancient herb with a potential nontoxic natural antioxidant efficacy. Oral intake and chewing betel leaves have an effort on the moving parts of salivary gland and induce salivation and de…

    5. Article

      Effects of the Mint Monoterpene (R)‑(+)‑Pulegone Evaluated by Functional Observational Battery: A Potential Short Method

      Yesica P Zaio, Marco M Mazzotta, Agripina Ramírez Sánchez, Elisa Alejandrina Gomez, María Paula Zunino, Andrés Alberto Ponce

      pp. 31–36 · DOI: 10.4103/pr.pr_115_18 · Published

      Background: Pulegone (PUL) is one of the major constituents of peppermint and pennyroyal. Objective:The main purpose of this study was to investigate the early effects of toxicity of PUL. Materials and Methods: We assess…

    6. Article

      A Study of In-vitro Hypoglycemic and Glucose Uptake Activity of Isolated Compound from Ethanolic Leaf Extract of Amaranthus tristis Linn

      T Sundarrajan, V Velmurugan, K Manikandan, D Jothieswari

      pp. 37–40 · DOI: 10.4103/pr.pr_119_18 · Published

      Background: Natural bioactive compounds have a long history to use effectively in the treatment of Diabetes Mellitus. Amaranthus tristis Linn (Amaranthaceae) have been used for the treatment of various ailments. Objectiv…

    7. Article

      Cytotoxicity and Apoptosis Induction of Sea Cucumber Holothuria atra Extracts

      Muhammad Nursid, Endar Marraskuranto, Ekowati Chasanah

      pp. 41–46 · DOI: 10.4103/pr.pr_3_18 · Published

      Context:Cancer is one of the major causes of death. Sea cucumbers are marine invertebrate that is widely used and utilized in traditional medicine. One of the most studied of sea cucumbers efficacy is its anticancer prop…

    8. Article

      Phytochemistry in Medicinal Species of Solanum L. (Solanaceae)

      Laudinéia de Jesus Matias, Juliana Almeida Rocha, Vanessa de Andrade Royo, Elytania Veiga Menezes, Afrânio Farias de Melo Júnior, Dario Alves de Oliveira

      pp. 47–50 · DOI: 10.4103/pr.pr_148_18 · Published

      Background: The genus Solanum L. is the largest of the family Solanaceae; it has used in food, ornamentation, and medicinal. Objective:This work had as objective to perform the phytochemical screening secondary metabolit…

    9. Article

      Participation of Cytokines, Opioid, and Serotoninergic Systems on Antinociceptive and Anti‑inflammatory Activities of Simira grazielae Peixoto (Rubiaceae)

      Gabriela Carmelinda Martins dos Santos, Mirza Nalesso Gomes Sanches, Douglas Siqueira de Almeida Chaves, Mário Geraldo de Carvalho, Raimundo Braz-Filho, Bruno Guimarães Marinho

      pp. 51–59 · DOI: 10.4103/pr.pr_99_18 · Published

      Background:Simira grazielae P. is widely found at Brazil.S. grazielaehave been used to treat pain and inflammation in the Northeast of Brazil. Objective: This study investigated the mechanisms of the extract and partitio…

    10. Article

      Assessments of Antioxidant, Antilipid Peroxidation, and In-vitro Safety of Derris scandens Vine Extracts from Southern Thailand

      Rawiwan Nooin, Pornsiri Pitchakarn, Chaturong Kanchai, Churdsak Jaikang

      pp. 60–66 · DOI: 10.4103/pr.pr_141_18 · Published

      Background: Derris scandens (DS) has been used in Thai traditional medicine recipes for musculoskeletal pain relief in Southern Thailand. Changing of terrain and climate affected its phytochemical constituents and led to…

    11. Article

      Determination and Quantification of p‑Coumaric Acid in Pineapples (Ananas comosus) Extracts using Gradient Mode RP-HPLC

      Wan Mazlina Md Saad, Rasdin Ridwan, Nur Syamimi Md Lasim, Nur Liyana Mohd Rapi, Fatimah Salim

      pp. 67–71 · DOI: 10.4103/pr.pr_154_18 · Published

      Background: Pineapple (Ananas comosus) is a good source of phenolic compounds such as p‑coumaric acid.P‑Coumaric acid is a hydroxycinnamic acid known to possess antioxidant, antimicrobial, antimutagenic, and immunoregula…

    12. Article

      High-temperature Condition Increases Lignanoid Biosynthesis of Schisandra chinensis Seeds via Reactive Oxygen Species

      Guo Huimin, Wang Jiahui, Gao Huiru, Meng Xiangcai

      pp. 72–77 · DOI: 10.4103/pr.pr_42_18 · Published

      Introduction:The herbal medicine used in many countries came mainly from the wild in the past; now, declining yield resource and laborious gathering result in prevailing cultivated medicine, with a result of prevailing i…

    13. Article

      Euphorbia hirta Methanolic Extract Displays Potential Antioxidant Activity for the Development of Local Natural Products

      Aziana Ismail, Maizan Mohamed, Yap Fon Kwei, Khoo Boon Yin

      pp. 78–85 · DOI: 10.4103/pr.pr_113_18 · Published

      Background: The level of free radicals, which counteract the capability of the antioxidant system in plant products, is often measured in advance for further promising antidisease effect. Objective:In this study, we soug…

    14. Article

      Saponin of Momordica cymbalaria Exhibits Anti‑Inflammatory Activity by Suppressing the Expression of Inflammatory Mediators in Lipopolysaccharide‑Stimulated RAW264.7 Macrophages

      Suman Samaddar, Raju Koneri

      pp. 8–13 · DOI: 10.4103/pr.pr_130_18 · Published

      Background: Inflammation is an intricate biological process that commonly occurs in response to pathologic stimuli, and natural products have potential in healing inflammation. However, the anti‑inflammatory of Momordica…

    15. Article

      Estimation and Comparison of Amount of Organic Acids from Dried Leaves of Garcinia cambogia, Garcinia indica, Garcinia xanthochymus, and Garcinia morella by High‑Performance Liquid Chromatography

      Madappa Machamada Bheemaiah, Bopaiah Ajjikuttira Kushalappa

      pp. 86–91 · DOI: 10.4103/pr.pr_159_18 · Published

      Background:Pharmacological properties of (‑)‑hydroxycitric acid (HCA) derived from plants are extensively investigated for preventing lipid storage and controlling appetite. The Garcinia species is most sought out specie…

    SHORT COMMUNICATION

    1. Communication

      Ashwagandha Reverses the Dieldrin‑induced Cognitive Impairment by Modulation of Oxidative Stress in Rat Brain

      Tandra Ghosh, Sanvidhan G Suke, Chandrashekhar Yadav, Rafat Ahmed, Basu Deb Banerjee

      pp. 92–97 · DOI: 10.4103/pr.pr_77_18 · Published

      Dieldrin (DLD) is an organochlorine pesticide heavily used in agriculture to control pests. Widespread exposures of DLD to human population are likely to contribute in neurological disorders. Withania somnifera (WSF), co…

    2. Communication

      Suppression of Polyps Formation by Saffron Extract in Adenomatous polyposis coliMin/+ Mice

      Kyoko Fujimoto, Tomoe Ohta, Hitomi Yamaguchi, Nguyen Huu Tung, Gen Fujii, Michihiro Mutoh, Takuhiro Uto, Yukihiro Shoyama

      pp. 98–101 · DOI: 10.4103/pr.pr_152_18 · Published

      Saffron (Crocus sativus L.) has been used both as a food additive for flavoring and coloring and in traditional medicine. Saffron extract and its main component crocin decrease the growth of several types of human cancer…