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    Phcog.Net PHARMACOGNOSY RESEARCH Volume 15 · Issue 2 · pp. 206–404
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    Cover: Pharmacognosy Research

    Pharmacognosy Research

    Volume 15, Issue 2

    · pp. 206–404 · 22 articles

    Volume
    15
    Issue
    2
    Published
    Pages
    206–404
    Articles
    22
    Sections
    2
    ISSN
    ISSN: Print - 0976-4836, Online - 0974-8490
    Journal
    Pharmacogn. Res.
    Review ArticleOriginal Article

    In this issue

    Review Article

    1. Review

      Role of Polyphenols and Flavonoids as Anti-Cancer Drug Candidates: A Review

      Medha Mohan Hegde, K Lakshman

      pp. 206–216 · DOI: 10.5530/pres.15.2.022 · Published

      Natural drug-based chemotherapeutic have advanced at an unprecedented rate over the past decade. Owing to protective roles in vegetation, and exceptional antioxidant qualities, polyphenols and flavonoids have demonstrate…

    2. Review

      Unexploited Potentials of Endophytic Fungi: Patents Review on Endophytic Fungi Related to Secondary Bioactive Compounds

      Priyatama V. Powar, Shilpa Chaudhari

      pp. 217–225 · DOI: 10.5530/pres.15.2.023 · Published

      Endophytic fungi are various micro-organisms that inhabit intracellular or intercellular plant tissues in symbiotic association [at certain stages of their life cycles], without causing damage or morphological changes. T…

    3. Review

      Water Lily (Nymphaea nouchali Burm. f): An Ancient Treasure of Food and Medicine

      Basani Kiranmai, Mondi Sandhyarani, Ashok Kumar Tiwari

      pp. 226–234 · DOI: 10.5530/pres.15.2.024 · Published

      Nymphaea nouchali(Syn.Nymphaea stellata Willd.) from family Nymphaeaceae, is a species of perennial aquatic flowering plant with huge round floating leaves and rhizomes. It is well-known and prominent herb in Ayurveda an…

    4. Review

      Novel Approaches for the Treatment of Drug-Resistant Tuberculosis

      Sonam Pushkar, Vibhav Varshney, Pushpendra Pushkar, Harish Kumar Sagar

      pp. 235–241 · DOI: 10.5530/pres.15.2.025 · Published

      Tuberculosis (TB) is a leading infectious disease that caused the deaths of a total of 1.5 million people in 2020 and is one of the top causes of death globally. India is a country with the highest TB burden, and it may …

    Original Article

    1. Article

      Investigating the Pharmacognostic and Pharmacological Activities of Azadirachta indica L. through Biochemical Assays

      Mamta Yadav, Smita Mishra, Ritu Tiwari, Bhavna Kumari, Mayank Shukla, Meenakshi Dahiya, Anil Teotia, Varsha Mehra, Vivekanandan Kalaiselvan, Rajeev Singh Raghuvanshi

      pp. 242–254 · DOI: 10.5530/pres.15.2.026 · Published

      Background:Azadirachta indicaL., commonly known as ‘neem’ is a member of the Mahagony family, widely available in Indian sub-continents. Neem tree is popularly known for its vast therapeutic properties such as antimicrob…

    2. Article

      Preparation of Camellia sinensis (Green Tea) and Acacia nilotica (Babul) Herbal Formulation and its Anti-Inflammatory Activity

      Amirtha Varshini, Anju Cecil, S. Rajesh Kumar

      pp. 255–257 · DOI: 10.5530/pres.15.2.027 · Published

      Introduction:Acacia nilotica is otherwise called Babul is multipurpose nitrogen fixing tree legume. Its roots are beneficial in treating tumors, cancer, and tuberculosis. One of the most consumed beverages in the world, …

    3. Article

      Abrogation of Acute Inflammation in ICR Mice with Topical Administration of Philippine Stingless Bee (Tetragonula biroi Friese) Honey

      Mark Joseph Maranan Desamero, Mikaela Bernadette Andres Rabino, Maria Angelica Rimas Tayao, Mary Jasmin Cabillon Ang, Jussiaea Valente Bariuan, Roxanne Posilero Gapasin, Therese Marie Avena Collantes, Melissa Marie Risos Rondina, Cherry Pambid Fernandez-Colorado, Cleofas Rodriguez Cervancia, Maria Amelita Celino Estacio

      pp. 258–266 · DOI: 10.5530/pres.15.2.028 · Published

      Background: Honey, a sweet sugar-rich bee-derived product, has been widely recognized in the realm of Ayurveda and Pharmacognosy for the treatment of various inflammatory conditions including inflammatory bowel disease, …

    4. Article

      Analytical Quality by Design (AQBD) Assisted Development and Validation of HPTLC Method for Estimation of Rottlerin in Topical Patch Formulation

      Kaumudee Bodas, Vaibhav M Shinde, Deshmukh Vishal, Deshmukh Sheetal

      pp. 267–276 · DOI: 10.5530/pres.15.2.029 · Published

      Background: Rottlerin, a natural polyphenolic ketone is a major constituent of Mallotus philippensis(Lam.) Mull. Arg. plant. Although, less explored it has diverse array of therapeutic applications. Objectives:The curren…

    5. Article

      Macro-microscopic and HPTLC Atlas of Canavalia gladiata (Jacq.) DC. Fruit

      Susikumar Sundharamoorthy, Gokula Kannan Sundharamoorthy, Achintya Kumar Mandal, Shakila Ramachandran, Senthilvel Govindaraju, Sunil Kumar Koppala Narayanan

      pp. 277–287 · DOI: 10.5530/pres.15.2.030 · Published

      Background:Canavalia gladiata (Jacq.) DC. (Family Leguminosae) is a large annual or perennial climber with a terete glabrous stem, native to Indo-Malaysian and also distributed in tropical, subtropical regions. C. gladia…

    6. Article

      Rubia cordifolia L. Crude Aerial Part Extracts Show a High Potential as Antimalarials against Chloroquine Resistant Plasmodium falciparum Strains in vitro

      Magara Jeremiah, Lucy Kamau, Grace Nyambati, Hastings Ozwara

      pp. 288–296 · DOI: 10.5530/pres.15.2.031 · Published

      Introduction: Plasmodium falciparum human malaria parasite is resistant to most available medicines in Africa, necessitating research for new drugs. Rubia cordifoliaL. is used in traditional malaria treatment in Kenya de…

    7. Article

      Essential Oils of Rosmarinus officinalis and Eucalyptus globulus Cultivated in the Mountainous Region of the State of Rio de Janeiro (Brazil): Chemical Profile and Antileishmanial Activity

      Rogéria Cristina Zauli, Tarcísio Martins Santos, Alberto Wisniewski Jr, Patrícia Xander, Aislan Cristina Rheder Fagundes Pascoal

      pp. 297–306 · DOI: 10.5530/pres.15.2.032 · Published

      The present study aimed to characterize the chemical profile of essential oils of Rosmarinus officinalis (EORo) and Eucalyptus globulus (EOEg) cultivated in the mountainous region of the state of Rio de Janeiro, Brazil, …

    8. Article

      Possible Involvement of Cellular Pathway and Cytokines in Manganese Induced Neurotoxicity in Neuroblastoma Cells via KH–Type Splicing Regulatory Protein

      Sharad Singh, Sunil More, G. S. Latha, Himanshu Agrawal, Veena S M, Francois Niyonzima

      pp. 307–314 · DOI: 10.5530/pres.15.2.033 · Published

      Background: Manganese is a toxic essential trace element and too high concentration instigates the neurodegenerative disease known as parkinsonism. Effects of manganese may lead to apoptosis. However, a detailed mechanis…

    9. Article

      Antidiabetic Potential and Chronic Toxicity of Hydroalcoholic Extract of Echeveria subrigida Leaves

      Belinda Heredia-Mercado, Francisco Delgado-Vargas, Lorenzo Ulises Osuna-Martínez, Elvic Noguera-Corona, José Ángel López-Valenzuela, Rosalio Ramos-Payán, Gabriela López-Angulo

      pp. 315–327 · DOI: 10.5530/pres.15.2.034 · Published

      Background:Echeveria subrigida extracts have biological activities of human health importance. However, the in vivo effects on glucose levels and chronic toxicity are unknown. Objectives: To analyse thein vivo hypoglycem…

    10. Article

      Screening and Evaluation of Potential Antifungal Plant Extracts against Skin Infecting Fungus Trichophyton rubrum

      Margret Kanimozhi A, Caroline Rose J

      pp. 328–337 · DOI: 10.5530/pres.15.2.035 · Published

      Dermatophytosis is mainly caused by Trichophyton rubrum. The use of presently available conventional antifungal agents is limited due to various side-effects, requirement of long-term application, emergence of resistant …

    11. Article

      Phytochemical, Antioxidant and Trace Element Analysis of Hypericum japonicum Thunb.

      Mritunjoy Kumar Roy, Ananta Swargiary

      pp. 338–346 · DOI: 10.5530/pres.15.2.036 · Published

      Background: Plants possess various bioactive compounds with many biological activities. Antioxidant plays vital roles in initiating deleterious free scavenging radical reactions. Objectives:The present study was done to …

    12. Article

      Effect of Glutathione Enriched Polyherbal Formulation on Streptozotocin Induced Diabetic Model by Regulating Oxidative Stress and PKC Pathway

      Sheethal S, Ratheesh M, Svenia P Jose, Sandya S

      pp. 347–355 · DOI: 10.5530/pres.15.2.037 · Published

      Background: Increasing evidence shows that oxidative stress is one of the root causes of metabolic disorders like diabetes. Glucose oxidation and activation of various metabolic pathways lead to a disproportionate genera…

    13. Article

      Total Polyphenolic Content, Antioxidant Activity and Chromatographic Profiling of Extracts of Ardissia solanacea

      Jyotsna Chopade, Asha Thomas, Sohan Chitlange

      pp. 356–362 · DOI: 10.5530/pres.15.2.038 · Published

      Background: The current study focuses on the preliminary phytochemical analysis, antioxidant potential and identification of phytochemicals in Ardissia solanacea leaves extract using chromatography and HR-MS. Materials a…

    14. Article

      Phytochemical Analysis and in vitro Antioxidant Potential of Aqueous and Ethanol Extracts of Irvingia gabonensis Stem Bark

      Catherine Otitolaiye, Akhere Omonkhua, Kelly Oriakhi, Edward Okello, Iyere Onoagbe, Friday Okonofua

      pp. 363–372 · DOI: 10.5530/pres.15.2.039 · Published

      Background: Irvingia gabonensis extracts are documented to possess antidiabetic, hypocholesterolemic, and antioxidant activities. The phytochemical components of medicinal plants are responsible for their therapeutic pro…

    15. Article

      HPLC-DAD Phenolic Composition, Antioxidant, Anticholinesterase, Antidiabetic and Anti-quorum Sensing Properties of Bitter Kola (Garcinia kola) and Kolanut (Cola acuminata)

      Sameh Boudiba, Selcuk Kucukaydin, Alfred Ngenge Tamfu, Kom Blaise, Aristide Mfifen Munvera, Yasmine Arab, Ozgur Ceylan, Rodica Mihaela Dinica

      pp. 373–383 · DOI: 10.5530/pres.15.2.040 · Published

      Background: Eating Cola acuminataand Garcinia cola nuts in African societies symbolizes in socio-cultural hospitality. They stimulate the nervous system, reduce fatigue and sleep. Objectives:To determine the phenolic com…

    16. Article

      Comparison of the Anti-asthmatic Potential of Himalayan Plants Lonicera obovata Royle and Morina longifolia Wall: An in vivo Study

      Pooja Boora, Richa Puri, Sushila Rani, Monika Mehta, Dechan Angmo

      pp. 384–391 · DOI: 10.5530/pres.15.2.041 · Published

      Background:Asthma is a very common and chronic disease in which there is an inflammation of the lungs. Inflammatory airways and narrowing, spasms, over-secretion of mucus, bronchoconstriction, and eosinophilic airway inf…

    17. Article

      Separation of Methanolic Leaf Extracts of Three Rutaceous Plants by Capillary Electrophoresis and High-Performance Liquid Chromatography Methods

      Chakravarthi Guntupalli, Narender Malothu, Ankarao Areti, Buchi N Nalluri, Praveen Sivadasu, Narayanarao Alla

      pp. 392–398 · DOI: 10.5530/pres.15.2.042 · Published

      Introduction: In the phytochemical analysis of various multi component mixtures, Capillary electrophoresis (CE) method was considered as the best alternative tool due to high efficiency resolution separations, low solven…

    18. Article

      Revealing Anti-Microbial Potential of Traditional Siddha Formulation Pancha Karpa Chooranam against Infectious Pathogens

      Sattanathan Iyswarya, Sampath Meena, Shanmugasundaram Visweswaran, Narayanan Jagathambal Muthukumar

      pp. 399–404 · DOI: 10.5530/pres.15.2.043 · Published

      Background: Infectious diseases are considered to be the most significant threat to human health due to the fact that they are responsible for one-half of all deaths in tropical countries. The majority of the currently a…