Cover: Pharmacognosy Research
Pharmacognosy Research
Volume 17, Issue 2
2025 · pp. 326–688 · 34 articles
- Volume
- 17
- Issue
- 2
- Published
- 2025
- Pages
- 326–688
- Articles
- 34
- Sections
- 2
- ISSN
- ISSN: Print - 0976-4836, Online - 0974-8490
- Journal
- Pharmacogn. Res.
In this issue
Review Article
- Review
A Comprehensive Review of Phytochemical and Pharmacological Appraisal of Cassia fistula Linn.
Tanvi Jangid, Aditya Jain, Gauri Shankar Bhardwaj, Ram Niwas Jangir
pp. 326–347 · DOI: 10.5530/pres.20251970 · Published 2025
The health of individuals living in developed and developing countries remain at risk due to the current global environmental pollution scenario, which is alarmingly leading to the rise in infectious and chronic diseases…
- Review
Phytopharmacological Insights into Ricinus communis: A Comprehensive Overview
Surya Nath Pandey, Prashant Kumar, Harishchandra Verma, Sumit Durgapal, Balwan Singh
pp. 348–357 · DOI: 10.5530/pres.20251940 · Published 2025
Medicinal plants are used in the traditional medicinal system and in Ayurveda globally. Euphorbiaceae is a large family which contains more than 3000 species. Ricinus communis or castor bean plant is well-known plant of …
- Review
Exploring the Therapeutic Potential of Natural Products in Obesity Treatment: Molecular Mechanisms and Isolation Techniques
Sandhya Jaiswal, Aaditee Sharma, Anjoo Kamboj, Jaspreet Kaur, Parminder Nain
pp. 358–369 · DOI: 10.5530/pres.20252016 · Published 2025
The present review focuses on the investigation of natural chemical constituents that contribute to anti-obesity activity, along with their mechanisms of action and potential therapeutic applications. Extensive literatur…
- Review
Unearthing the Modulatory Operations of Phytochemicals: A Reliable Framework for Therapeutic Approaches
Ayodeji Benjamin Akawa, Isaac Adekola Adu, Ibrahim Abayomi Yekini, Ilesanmi Kayode Fasuba, Oluranti Esther Olaiya
pp. 370–379 · DOI: 10.5530/pres.20252043 · Published 2025
Phytochemicals in no small measure confer active roles in human survival as well as in the prevention of various diseases by their effortless ability to combat oxidative stress known to shorten life expectancy in humans.…
- Review
Recent Advances in Transdermal Drug Delivery System and its Utilization in Herbal Medicines
Ravishankaran Subash, Sundaramoorthi Revathi, Shanmugam Akilandeswari
pp. 380–384 · DOI: 10.5530/pres.20252044 · Published 2025
Transdermal delivery systems are one type of treatment for a variety of disorders that can be utilized as an alternative to invasive procedures. Pharmaceutical preparations are incorporated into transdermal delivery syst…
- Review
Interaction between Anti Diabetic Drugs and Herbs: A Review
Ruchika Mourya, Rajesh Sharma
pp. 385–401 · DOI: 10.5530/pres.20252023 · Published 2025
Diabetes is a long-term medical disorder characterized by elevated blood glucose levels due to inadequate insulin use. It is caused by a pathogenic process that results in insulin insufficiency due to the death of β-cell…
- Review
Exploring the Role of Phytoconstituents for Endocrine Disorder: A Review
Shweta Bhandari, Rahul Trivedi, Vishal Garg, Ajay Saini, Manish Gupta, Ram Singh
pp. 402–410 · DOI: 10.5530/pres.20252070 · Published 2025
The endocrine system consists of various glands responsible for secreting hormones that regulate metabolism, growth, reproduction, and other physiological processes. Disruptions in this system, termed endocrine disorders…
- Review
Advancements in Quantitative and Qualitative Methods for Quality Control of Herbal Drugs: A Comprehensive Review
Seema Devi
pp. 411–415 · DOI: 10.5530/pres.20252077 · Published 2025
The quality control of herbal drugs is a critical aspect of ensuring their safety, efficacy and reliability. The complex composition of herbal products, influenced by environmental, genetic and processing factors, necess…
- Review
Mechanistic Role of Phytophenolic Acids in the Management of Alzheimer’s Disease: A Comprehensive Review
Abhishek Pete Nagaraj, Annegowda Hardur Venkatappa, Jayashree Kallukombari Ramakrishna, Purushotham Karadigere Nagaraju, Bevinahalli Ramesh, Noor ul Eain
pp. 416–426 · DOI: 10.5530/pres.20250001 · Published 2025
Alzheimer’s Disease (AD) or dementia, is a brain illness, which is chronic and non-reversible and is related to advanced memory loss, cognitive decline and altered behaviour. Current treatments including synthetic agents…
- Review
Bovine Milk Proteins and Human Health: Unveiling Interplay, Surmounting Challenges and Future Prospects
Nimmambattu Mohana Rupa, Veena Sunil More, Archana Sripadarao Rao, Ajay Nair, Divyashree Arun, Sunil Shivajirao More
pp. 427–439 · DOI: 10.5530/pres.20252072 · Published 2025
This review explores our current understanding of bovine milk proteins, examining their structural architecture and their impact on human health, particularly in enhancing milk quality. Recent advancements have illuminat…
- Review
Unveiling the Phytochemical Profile and Therapeutic Benefits of Solanum xanthocarpum: A Systematic Review
Nem Kumar Jain, Shubham Anand, Priyanka Kesari, Rekha Rani, Santosh Kumar, Akanksha Tiwari, Moti Lal, Devendra Dhanorya, Aman Sharma, Sakshi Singh, Manoj Kumar Bajhaiya
pp. 440–451 · DOI: 10.5530/pres.20252059 · Published 2025
Solanum xanthocarpum, a significant medicinal plant in traditional systems of medicine, possesses a rich phytochemical profile that contributes to its diverse therapeutic applications. This review explores the bioactive …
- Review
The Ocean's Treasure Trove: Bioactive Compounds from Sea Sponges
Sheetal Sadguru Samant, Anvay Ashok Satpute, Mikhil Prasad Mayekar, Shamita Shamsundar Loke, Shweta Nitin Bhatkar, Mohammad Saad Golandaj, Tanvi Deepak Rawool, Vijay Arjun Jagtap
pp. 452–461 · DOI: 10.5530/pres.20252085 · Published 2025
Sea sponges are among the oldest living creatures on Earth that have evolved complex chemical defenses to thrive in the ocean's competitive environment. These marine animals have developed an impressive array of bioactiv…
- Review
Exploring the Male Antifertility Potential of Medicinal Plants: A Comprehensive Review
Gauri Shankar Bhardwaj, Aditya Jain, Tanvi Jangid, Ram Niwas Jangir
pp. 462–488 · DOI: 10.5530/pres.20252092 · Published 2025
Population growth is one of the biggest issues facing by the globe today, particularly in developing nations where it will certainly have an impact on the environment, public health and the economy. In market numerous bi…
- Review
A Comprehensive Review on Medicinal Herbal Plant with Potential Hypolipidemic Activity
Devendra Dhanorya, Vikas Pnadey, Rajesh Shukla, Yuvraj Vishwakarma, Gourav Kumar Bairagi, Vandana Gupta, Pushpender Bardiya, Shivam Kumar Kori, Priyansh Patel, Nishant Kumar Bardiya, Shikha Bhalla, Shubham Anand
pp. 489–506 · DOI: 10.5530/pres.20252009 · Published 2025
Hyperlipidaemia, characterized by elevated blood lipid levels, is a significant risk factor for cardiovascular diseases. While traditional pharmacological treatments are available, their effectiveness and potential side …
Original Article
- Article
Standardization and GC-MS Analysis of Phytochemicals in Coccinia indica (Wight and Arn.) Fruits
Shadab Alam, Mohammad Irfan Khan, Aleza Rizvi, Badruddeen, Juber Akhtar, Mohammad Ahmad, Mohammad Dabeer Ahmad
pp. 507–518 · DOI: 10.5530/pres.20251942 · Published 2025
Background Coccinia indica, commonly known as the ivy gourd, is traditionally utilized for its diverse medicinal properties. Objectives The objectives of the study were to standardize and evaluate the fruits of Coccinia …
- Article
Phyto-Analytical Studies and in vitro Wound Healing Activity of Synedrella nodiflora (L.) Gaertn Leaf Extract
Joshna Koodathil, Lathika Ramadass, Sindhu Jayachandran, Jaganath Sekar
pp. 519–531 · DOI: 10.5530/pres.20251916 · Published 2025
Background Traditionally among the Nigerian population Synedrella nodiflora is prominently used for treating Putrefied Wound. Objectives The present work was designed to evaluate the In vitro Wound healing activity of Sy…
- Article
Syringic Acid Ameliorates Bleomycin Induced Pulmonary Inflammation and Fibrosis in Rats via Maintenance of Endogenous Antioxidants and Downregulation of Pro-Inflammatory Markers
Bhupatiraju VS Lakshmi, Krupa Varam Bethala
pp. 532–542 · DOI: 10.5530/pres.20251990 · Published 2025
Background Chronic administration of Bleomycin (BLM), a chemotherapeutic drug, has been linked to Idiopathic Pulmonary Fibrosis (IPF). It has been observed that syringic acid, a phenolic compound, has antiapoptotic, anti…
- Article
An Evaluation of the Oral Toxicity of Shwaskas Chintamani Rasa in Wistar Rats for 90-Days Repeated Administration
Mahalaxmi Mohan, Shubhangi Hemraj Pawar, Sanskruti Sanjay Kashmire, Shishir Purushottam Pande, Rajshree Abhay Kulkarni, Abhay Narayan Kulkarni
pp. 543–551 · DOI: 10.5530/pres.20251945 · Published 2025
Objectives Toxicological research employing Herbo-Metallic (HM) medicine is essential to confirm that such medication has no harmful effects on humans. Despite the fact that the mercury level in Shwaskas Chintamani rasa …
- Article
Exploring the Therapeutic Potential of Plectranthus amboinicus: LC-MS Profiling and Molecular Docking Insights
MH Shaeena, DR Bharathi
pp. 552–561 · DOI: 10.5530/pres.20251961 · Published 2025
Introduction Plectranthus amboinicus is noted for its diverse phytochemical profile, which includes various semi-polar compounds and significant secondary metabolites. These compounds may offer therapeutic benefits for d…
- Article
Cyperus esculentus Ameliorates Cadmium Chloride Induced Testicular Toxicity in Male Rats Following Male Reproductive Hormone, Pro-Inflammatory and Anti-Inflammatory Analysis
Justina Nwandimma Nwangwa, Ekementeabasi Aniebo Umoh, Esu Ukpai Enene, Augustine Lishilinimye Udefa1
pp. 562–570 · DOI: 10.5530/pres.20252033 · Published 2025
Background Cyperus esculentus has been reported to mitigate testicular dysfunction associated with lead and salt diet. However, it is not known if it can mitigate or protect the testis from cadmium toxicity. This researc…
- Article
Modulatory Effects of Passiflora edulis on Liver Function, Lipid Profile and Adipokines in Fructose-Induced Metabolic Syndrome in Rats
Kinjal P. Patel, Rajesh A. Maheshwari
pp. 571–576 · DOI: 10.5530/pres.20252058 · Published 2025
Background This research explores the restorative effects of Passiflora edulis extract counter to liver damage and metabolic disruptions caused by a high-fructose diet in female Wistar rats. Materials and Methods The con…
- Article
Assessment of Quality Control Parameters of Erandamoola Kwatha, Dhanvantari Taila and Yogaraja Guggulu in the Management of Non-specific Backache
Ramesh Killedar, Pradeep Shindhe, Veena Kupati, Vijay Kage
pp. 577–580 · DOI: 10.5530/pres.20252052 · Published 2025
Background Ayurveda is an ancient system of medicine that promotes health and healing by using natural components. Quality and standardisation are essential to ensure the therapeutic efficacy and safety of Ayurvedic medi…
- Article
Bioactive Constituents of Curcuma amada Roxb. Rhizome and its Antimicrobial Activity against Food Spoilage Microorganisms
Rashmi Shahi, Suvarna V. Chavannavar, Veena S. Anil, N Bharath Kumar
pp. 581–587 · DOI: 10.5530/pres.20252063 · Published 2025
Background Curcuma amada Roxb. is popularly known as mango ginger due to its morphological similarity to ginger but has raw mango characteristics. It is well known for its several medicinal and pharmacological activities…
- Article
In vitro Assessment of Antioxidant and Cytotoxic Effects of Argemone mexicana and Prosopis cineraria Methanolic Extracts against Hepatocellular Carcinoma and Glioblastoma Cells
Divya Vashishth, Sudhir Kumar Kataria
pp. 588–596 · DOI: 10.5530/pres.20252073 · Published 2025
Objectives The antioxidant and anti-proliferative properties of Argemone mexicana and Prosopis cineraria were investigated against Hepatocellular carcinoma (HepG2) and glioblastoma (U87MG) cells. Materials and Methods Me…
- Article
Green Synthesis of Silver Nanoparticles from Secamone emetica: Characterization and Assessment of Antioxidant, Anti-Diabetic and Anti-Cancer Activities against MCF-7 Breast Cancer Cells
S. Shalini, N. Sudeepthi, DH. Geetha, R. Jayashre
pp. 597–607 · DOI: 10.5530/pres.20252064 · Published 2025
Background Green-synthesized nanoparticles offer eco-friendly advantages over physical and chemical methods, utilizing plant extracts as natural capping, reducing and stabilizing agents. While Secamone emetica is renowne…
- Article
Bioactive Compounds in Inocutis levis and their Cytotoxic Effects on MCF-7 and HT-29 Cancer Cells
Fereshteh Mir Mohammad Rezaei, Fatemeh Tavakoli, Maryam Kiaei, Vahid Ramezani, Amin Zarezadeh, Masoumeh Ghobad-Nejhad
pp. 608–618 · DOI: 10.5530/pres.20252069 · Published 2025
Background and Objectives Fungi are undeniable sources of all types of secondary metabolites and bioactive compounds. Inocutis levis is a polypore fungus belonging to Hymenochaetales of basidiomycetes. This study aimed t…
- Article
Identification and Quantification of Four Bioactive Markers in Sanjivani Vati Using High-Performance Thin Layer Chromatography
Shreshtha Kaushik, Nikhil Mehere, Mohit Upadhyay, Pramod Yadav, Pradeep Kumar Prajapati
pp. 619–626 · DOI: 10.5530/pres.20252093 · Published 2025
Background Sanjivani Vati (SV) is an extensively used multicomponent Ayurvedic medicine, recommended for fever, indigestion, dysentery, gastroenteritis and more. The pharmaceutical standardization of SV and estimation of…
- Article
Isolation, Characterization and Structural Elucidation of a Bioactive Flavonoid from Schinus polygama Leaves Using Chromatographic and Spectroscopic Techniques
Chandra Prakash Bhardwaj, Piush Sharma, Maneesh Napit
pp. 627–637 · DOI: 10.5530/pres.20252098 · Published 2025
Aim Isolation, Characterization and Structural Elucidation of a Bioactive Flavonoid from Schinus polygama Leaves Using Chromatographic and Spectroscopic Techniques is the aim of present study. The process of separating a…
- Article
In vitro Cytotoxicity Evaluation of Hardwickia binata Roxbs against Human Breast Cancer Cell Line MCF-7 and Human Cervical Cancer Cell Line HeLa
Snehal Praful Shingade, Rajendra Baliram Kakde
pp. 638–644 · DOI: 10.5530/pres.20252008 · Published 2025
Hardwickia binata belongs to the family Caesalpiniaceae is used traditionally folklore remedies for a variety of illnesses, such as fungus, gram-positive and gram-negative bacteria, cancer, diarrhoea, leprosy, worm infec…
- Article
Microscopical Investigation of Punica granatum L. Flower: A Traditional Drug with Vivid Therapeutic Promise
Sonam Tamchos, Talat Anjum, Rama Rao, Shiddamallayya Nagayya, Gopesh Sharma
pp. 645–653 · DOI: 10.5530/pres.20252086 · Published 2025
Background The present study was conducted to lay down the microscopic examination of Punica granatum L. flower. This taxon's leaves, flowers, fruits and bark are known to possess medicinal properties. It is rich in vita…
- Article
Evaluation of in vitro Anti-Inflammatory Activity of Trichosanthes palmata against the Denaturation of Protein
Arshu Pirmhommad Patel, Sayee Promod Dhavan, Tejasvee Ramchandra Shinde, Manisha Dhondiram Sonawane, Hetali Amrutbhai Patel, Nilima Mahesh Wani
pp. 654–658 · DOI: 10.5530/pres.20252089 · Published 2025
Background Trichosanthes palmata Lour. (Cucurbitaceae) is one of the important medicinal plants used traditionally for the treatment of asthma, earache, ophthalmia, leprosy, fever as well as used in the treatment of migr…
- Article
Evaluation of Pistachio Extract Standardized to 1% Melatonin on Pentobarbital Sodium-Induced Sleep in Swiss Albino Mice
Hebbani Nagarajappa Shivaprasad, Sravani Thimmannagari, Tharun Mariswamy, Cherupalli Sree Ramya, Madhu Krishnamani, Gaurav Soni
pp. 659–664 · DOI: 10.5530/pres.20252094 · Published 2025
Background Pistachios are rich in melatonin, vitamins and antioxidants, which are known to have potential sedative and hypnotic properties. Previous studies suggest that melatonin, a hormone involved in regulating the sl…
- Article
Synergistic Effects of Guan-Xin-Er-Hao and Hydroxysafflor Yellow A on Atherosclerosis in ApoE-/- Mice: Unveiling Antioxidant and Anti-Inflammatory Mechanisms
Wenya Huang, Le Zhang, Li Zhou, Zhifang Cai, Kaige Wu, Yu Wang, Runze Zhou, Min Xu, Jia Li, Yunke Huang, Ping Ren, Xi Huang
pp. 665–678 · DOI: 10.5530/pres.20252095 · Published 2025
Background The Guan-Xin-Er-Hao (GXII) decoction, a traditional Chinese medicine, contains hydroxysafflor yellow A (HSYA) as its main active compound for treating coronary heart disease. Objectives This study aimed to ass…
- Article
FTIR Analysis, Total Phenolic Content, Antioxidant and Antidiabetic Activities of Hildegardia populifolia (Roxb.) Schott and Endl. (Malvaceae)
Satyavarapu Veera Venkata Naga Satya Mahalakshmi, Durga Bhavani Penmetsa, Kondal Reddy Yennam, Sadasivaiah Byalla
pp. 679–688 · DOI: 10.5530/pres.20252113 · Published 2025
Background Diabetes has become a major public health issue in developing countries, with rising prevalence in urban populations. Type II diabetes, the most common form, can be managed with medication, diet and exercise. …