Volume 17, Issue 3

Jul-Sep 2025 · pp. 689–1076 · 42 articles

Volume: 17
Issue: 3
Published: Jul-Sep 2025
Pages: 689–1076
Articles: 42
Sections: 2
ISSN: ISSN: Print - 0976-4836, Online - 0974-8490
Journal: Pharmacogn. Res.

Original Article Review Article

In this issue

Original Article

Article
Xylopia aethiopica Fruit Macerate Inhibits Carrageenan-induced Pleurisy in Rats
Gnatoulma Katawa, Fagdéba David Bara, Foulounanna Daria, Pélagie Edlom Tchadie, Tégmaba Gnodja, Kathrin Arndts, Komlan Batawila, Manuel Ritter
pp. 1005–1019 · DOI: 10.5530/pres.20252238 · Published Jul-Sep 2025
Background Pleurisy is an inflammatory condition of the pleura that can lead to severe morbidity and mortality. Controlling excessive pleural inflammation is crucial. Xylopia aethiopica, known for its anti-inflammatory p…
Article
Antioxidant, Stimulating Telomerase and Anxiolytic Activities of Polysaccharide Isolated from Sargentodoxa cuneata
Jian Tang, Ping Zhou, Huifang Sun, Xiuquan Xu, Chongwei Wen, Haiping Xia
pp. 1020–1028 · DOI: 10.5530/pres.20252269 · Published Jul-Sep 2025
Background The classic anxiolytics have adverse effects in the treating anxiety disorders. Aim To identify the anxiolytic polysaccharide from Sargentodoxa cuneata. Materials and Methods The water-soluble Polysaccharide F…
Article
Evaluation of the Effects of Aerial Parts of Hydro-Alcoholic Extract of Tanacetum kotschyi and Dextromethorphan on Morphine Withdrawal Symptoms
Leila Balaneshin Kordan, Bohloul Habibi Asl, Yadollah Azarmi, Meysam Balaneshin Kordan, Solmaz Asnaashari
pp. 1029–1036 · DOI: 10.5530/pres.20252241 · Published Jul-Sep 2025
Background There are different mechanisms of dependence and tolerance to opioids. Dextromethorphan is a non-competitive N-Methyl-D-Aspartate (NMDA) glutamate receptor antagonist, whereas Tanacetum kotschyi (T. kotschyi) …
Article
Evaluation of Structural, Physical and Cytotoxicological Properties of Cissus quadrangularis, Carrageenan and Extracellular Matrix Based Guided Tissue Regeneration Membrane
Balaji Ganesh Subramanian, Uma Maheswari, Gurumoorthy Kaarthikeyan, Taniya Mary Martin, Meenakshi Sundaram Kishore Kumar
pp. 1037–1043 · DOI: 10.5530/pres.20252234 · Published Jul-Sep 2025
Background Bone tissue engineering has increasingly focused on developing bioactive composite membranes from natural polymers to enhance periodontal regeneration. This study aimed to compare the structural, physical, and…
Article
Development and Validation of an HPLC Method for Diosgenin, A Bioactive Compound in the Rhizomes of Chamaecostus cuspidatus
Hit Saliya, Jagdish Madam, Harsh Patel, Mihir Lakhani, Vivek Patel, Lakhandeep Shah, Vidhi Vyas, Mamta Shah
pp. 1044–1049 · DOI: 10.5530/pres.20252199 · Published Jul-Sep 2025
Chamaecostus cuspidatus is an important medicinal herb, with rhizomes which are rich in diosgenin content and are mainly used as an antidiabetic and anticancer. Diosgenin is a steroidal sapogenin (5α-Spirosten-3β-ol) and…
Article
Phytochemical Extraction, Screening, GCMS Analysis and Antioxidant Properties of Ophiorrhiza recurvipetala
Venkatakrishnan Vidya, Arokiasamy Justin Thenmozhi, Ravi Surya, Asokan Prema, Thamilarasan Manivasagam
pp. 1050–1061 · DOI: 10.5530/pres.20252230 · Published Jul-Sep 2025
Background and Objectives Most of the people from developing countries depend on plant-based ailments for several diseases due to the occurrence of pharmacological bioactive substances with lowered adverse effects. Ophio…
Article
Pharmacognostical and Phytochemical Screening of Leaves of Cajanus Scarabaeoides (L.) Thouars
Siddharth Krushnat Katkole, Varsha Dilip Jadhav
pp. 1062–1070 · DOI: 10.5530/pres.20252303 · Published Jul-Sep 2025
Background The plant Cajanus scarabaeoides (L.) Thouars has potent medicinal values. It has wound healing, anti-diabetic, anti-bacterial, anti-inflammatory, anti-diarrheal, hepatoprotective activities. Objectives Pharmac…
Article
GC-MS Analysis of an Ayurveda Formulation Erandamula Niruha Basti (Medicated Therapeutic Enema)
Anil Koralli, Pradeep L Gramapurohit, Sunil Jalalpure, Kshama Mutalik, Rashmi
pp. 1071–1076 · DOI: 10.5530/pres.20252174 · Published Jul-Sep 2025
Background The scientific credibility of modern and Indian System of Medicine, such as Ayurveda and Siddha, is highly relevant in the current era. The gas chromatography-mass spectrometry (GC-MS) instrument separates che…
Article
Pharmacological Investigation of Actinidia deliciosa Extract in NSAIDs Induced Gastric Ulcer in Rodent Model
Arijit Chaudhuri, Arushi, Manisha Dhiman, Anshul Thakur, Risha Kumari, Seema Devi, Shilpa Thakur, Ayusha, Prince, Nidhika
pp. 801–815 · DOI: 10.5530/pres.20252087 · Published Jul-Sep 2025
NSAIDs or non opoidal agents are commonly employed to treat rubor, dolor, relieve pain, but they often cause Gastrointestinal (GI) side effects, including gastritis, ulceration and bleeding. Natural products have emerged…
Article
Green Synthesis and in vitro Insights of Zinc Oxide Nanoparticles Using Nutmeg and Flaxseed Extracts
Mohamed Thaha, Johnisha Harris John Manohar, Arvina Rajasekar
pp. 816–822 · DOI: 10.5530/pres.20252068 · Published Jul-Sep 2025
Background Among various nanomaterials, Zinc Oxide Nanoparticles (ZnO NPs) have gained significant attention due to their unique properties. Traditional methods for synthesizing ZnO NPs often involve hazardous chemicals …
Article
Formulation and Evaluation of Azadirachta indica Taste Masked Oral Pellets for Gut Microbiome Modulation
Sarika Ankushrao Nikam, Priyatama Vijaysing Powar, Vaibhav Ravindra Vaidya, Devendra Shriram Shirode, Akshaykumar A. Sankaye, Neetu Ashok Khatri
pp. 823–830 · DOI: 10.5530/pres.20252118 · Published Jul-Sep 2025
Introduction Azadirachta indica has long been known for its therapeutic benefits, which include immunomodulatory and antibacterial activities. Human health is greatly influenced by the gut microbiota, and disturbances wi…
Article
Synthesis and Pharmacological Evaluation of Novel Formulation of Opiorphin and Lysozyme: An in vitro Study
Vimalasubhashini Vivekbalamithran, Abilasha Ramasubramanian, Saheb Ali
pp. 831–835 · DOI: 10.5530/pres.20252125 · Published Jul-Sep 2025
Background The antibacterial, anti-inflammatory and antioxidant properties of opiorphin and lysozyme are vital for health maintenance and disease prevention. Opiorphin reduces oxidative stress by neutralizing free radica…
Article
Formulation and Characterization of a Polyherbal Sunscreen Containing Camellia sinensis, Vitis vinifera, and Silybum marianum Extracts
Nandhini Jayaprakash, Sumathi Arumugam, Balan Paramasivam, Suriyaprakash Timmakondu Narasimhan Kuppusamy, Saravanan Jayaraman, Parthasarathi Venkateasan, Sridevi Rajendran, Karthikeyan Elumalai
pp. 836–849 · DOI: 10.5530/pres.20252128 · Published Jul-Sep 2025
Background and Objectives Prolonged Ultraviolet (UV) exposure induces oxidative stress, leading to inflammatory skin disorders in photosensitive individuals. This study aimed to develop and evaluate a polyherbal sunscree…
Article
Thymoquinone-Loaded Zinc Nanoparticles Mitigate Inflammation and Inhibit Glioblastoma Progression: A Novel Therapeutic Approach
Sofia Sebastian, Taniya Mary Martin, Meenakshi Sundaram Kishore Kumar
pp. 850–858 · DOI: 10.5530/pres.20252143 · Published Jul-Sep 2025
Background Glioblastoma is the most aggressive and lethal primary brain tumour, characterized by rapid proliferation, high invasiveness, and resistance to conventional therapies. Chronic inflammation plays a crucial role…
Article
Instrumental Characterization of Black Soot of Glycyrrhiza glabra: A Colouring Pigment for Eye Cosmetics
Geeta Govindappa Gadad, Bhumika Sundar
pp. 859–866 · DOI: 10.5530/pres.20252172 · Published Jul-Sep 2025
Background Añjanaṃ (collyrium) in Ayurveda is predominantly centered around its role in maintaining eye health rather than cosmetic use. This aligns with the traditional kohl/kajal application, prepared using herbs rich …
Article
Fumaria parviflora Lam. Aqueous Extract Versus Simethicone in the Treatment of Infantile Colic: A Prospective Randomized Clinical Trial
Vahid Ramezani, Mahmood Noori Shadkam, Mobina Ghiasirad, Sayedeh Ebrahimi, Ali Mohammad Ranjbar
pp. 867–872 · DOI: 10.5530/pres.20251909 · Published Jul-Sep 2025
Background infantile colic observes 10 to 40% of infants during first few months of life. Objectives The purpose of the present study was to evaluate the effectiveness of Fumaria parviflora Lam. (will fumitory) aqueous e…
Article
Exploring the Anthelmintic and Krumighna Properties of Vitex negundo Linn. (VN) for Indian Earthworms and Annelid Worms
Bhushan Deoraoji Mhaiskar
pp. 873–880 · DOI: 10.5530/pres.20252124 · Published Jul-Sep 2025
Introduction Helminth infections are a global health concern, especially in underdeveloped regions, contributing to anemia, malnutrition, and cognitive issues. Drug resistance to conventional anthelmintics like Albendazo…
Article
Phytochemical Profiling, Antioxidant and Antimicrobial Activities of a Traditional Polyherbal Formulation Containing Citrus limon, Bergera koenigii, Citrus medica and Andrographis paniculata
Muthuswamy Gnanadeepan, Kunnathur Murugesan Sakthivel, Rajan Radha Rasmi, Venkatraman Thirumalai, Kumar Pavithra, Kannikaparameswari Nachimuthu
pp. 881–895 · DOI: 10.5530/pres.20252131 · Published Jul-Sep 2025
Background Polyherbal formulations combining medicinal plants are widely studied for their enhanced therapeutic potential. Materials and Methods This study evaluates a polyherbal formulation containing leaves of Citrus l…
Article
Phytochemical Insights and Bioactive Potentials of Alstonia scholaris, a Variety from Mizoram, India: Studies of the Antioxidant and Anti-Infective Properties
Lalngaihmanawmi, Pawi Bawitlung Lalthanpuii, Lalbiakngheti Tlau, Lucy Lalawmpuii, Lalrosangpuii, Lalnundanga, Kholhring Lalchhandama
pp. 896–908 · DOI: 10.5530/pres.20252145 · Published Jul-Sep 2025
Background A distinct variety of Alstonia scholaris in Mizoram, Northeast India, is a medicinal plant applied in the remedy of various ailments, including diarrhoea, dysentery, gastrointestinal infections, malaria and wo…
Article
GC-MS Analysis and in vitro Anti-Dandruff Activity of Phyla nodiflora against Malassezia furfur
Priyanka Manmode, Dighe Santosh Bhausaheb
pp. 909–913 · DOI: 10.5530/pres.20252156 · Published Jul-Sep 2025
Background The common skin ailment known as dandruff mostly affects the scalp. It will impact nearly half of the prepubescent population, regardless of gender or race. The fungus Malassezia globosa, which is unique to th…
Article
Spectrophotometric SPF Assessment and Phytochemical Screening of Pleiogynium cerasiferum Leaf Extracts
Bhawana Bhatt, Sudhakar Kaushik, Heena Mittal, Lata Sati
pp. 914–919 · DOI: 10.5530/pres.20252165 · Published Jul-Sep 2025
Background Concerns over the environmental impact and potential health risks associated with synthetic Ultraviolet (UV) filters have intensified the search for natural, eco-friendly alternatives in sun protection formula…
Article
Safawi Date Extract Ameliorated Diabetogensis and Nephrotoxicity Induced by Propyl Paraben in Rats
Abdulrahman L. Al-Malki
pp. 920–926 · DOI: 10.5530/pres.20252173 · Published Jul-Sep 2025
Objectives The Parabens are synthetic compounds used as antibacterial and antifungal preservatives in many products. The nephrotoxicity and diabetogenic development during exposure of rats to propyl paraben and role of o…
Article
Fabrication of Snail Mucin-Silk Fibroin Hydrogel Scaffold for Guided Tissue Regeneration: A Zebrafish Fin Model Study
Sofia Sebastian, Bargavi Purushothaman, Pratibha Ramani
pp. 927–933 · DOI: 10.5530/pres.20252176 · Published Jul-Sep 2025
Background Scaffolds play a pivotal role in guiding tissue regeneration by providing a suitable environment for cell growth, migration, and differentiation. Among various materials, biopolymers such as silk fibroin and s…
Article
Comparative Efficacy of Different Solvent Extracts of Equisetum diffusum Whole Plant in FCA-induced Arthritic Rat Model
Sourav Sarkar, Barnana Chakrabarti, Debabrata Modak, Roopsa Datta, Soumen Bhattacharjee
pp. 934–946 · DOI: 10.5530/pres.20252179 · Published Jul-Sep 2025
Background Equisetum diffusum D. Don (Family Equisetaceae, common name ‘Himalayan horsetail’) is one such medicinally important herb that has a long history of traditional use among different tribal populations of the su…
Article
Phytochemical Profiling, HPLC Analysis and Antioxidant Activity of Lantana camara Flower and Leaf Extracts
V Mahesh., B. P. Harini
pp. 947–954 · DOI: 10.5530/pres.20252180 · Published Jul-Sep 2025
Background The current study aims to find the phytochemicals, antioxidants and amount of flavonoid present in different extracts of Lantana camara Linn. flower and leaf collected from in and around Bangalore University. …
Article
GC-MS Analysis of Dhanwanthari Taila: Identification of Bioactive Compounds Supporting its Analgesic and Anti-Inflammatory Potential in Chronic Low Back Pain
Ramesh Shivappa Killedar, Pradeep Shahjirao Shindhe, Vijay Kage, Raj Joshi
pp. 955–960 · DOI: 10.5530/pres.20252192 · Published Jul-Sep 2025
Background The scientific validation of traditional Ayurvedic formulations is crucial for integrating them into modern therapeutic practices. Dhanwanthari Taila, a widely used Ayurvedic medicated oil, is traditionally us…
Article
Potent in vitro Antioxidant, Antimicrobial, and Antidiabetic Effects of a Polyherbal Mixture: Evidence from 3T3-L1, β-TC6, and C2C12 Cell Line Studies
Dharmendra Pradhan, Santosh Kumar Ranajit, Prafulla Kumar Sahu, Sandip Chatterjee
pp. 961–972 · DOI: 10.5530/pres.20252220 · Published Jul-Sep 2025
Aim and Objectives The traditional plants Plumeria pudica, Podranea ricasoliana, and Leea macrophylla have been used for their medicinal properties since ancient times. Our main objective is to identify the preliminary c…
Article
Chitin Derivative from Marine Source Artemia franciscana Cysts Inhibits Colorectal Adenocarcinoma Cells by Regulating Apoptotic Mediators
Rajendran Poovazhagi, Subramani Thirunavukkarasu, Jeferson Stanley Santhosh, Kasi Lakshmanan, Anand Javee, Cecileya Jasmin Meshak Dhanashekaran, Narayanaswamy Radhakrishnan, Venugopal Vinod Prabhu, Kunnathur Murugesan Sakthivel, Rajan Radha Rasmi, Jiang-Shiou Hwang
pp. 973–982 · DOI: 10.5530/pres.20252138 · Published Jul-Sep 2025
Background Chitin is widely preferred in biomedical application due to its biocompatible and biodegradable nature. Naturally occurring chitin is a potential antimicrobial agent and plays a major role in degrading outer s…
Article
Phytochemical-Infused Chitosan Biocomposites: Cytotoxic, Antidiabetic, and Anticoagulant Potential of Vaccinium and Zingiber Extracts
Maria Sharon Velraj, Arvina Rajasekar
pp. 983–988 · DOI: 10.5530/pres.20252284 · Published Jul-Sep 2025
Background The integration of plant-derived bioactives with natural polymers offers a sustainable approach to therapeutic biomaterials. Vaccinium sect. Cyanococcus (blueberry) and Zingiber officinale (ginger) are known f…
Article
Comparative Study on Phytochemical, Antioxidant properties, Heavy Metal and FT-IR Analysis of Azadirachta indica L. from IMFA Industrial Area, Rayagada District, Odisha
Sabir Kumar Behera, Suraj Kumar Behera, A. Leelaveni
pp. 989–996 · DOI: 10.5530/pres.20252275 · Published Jul-Sep 2025
Background Various plant parts are utilized in traditional medicine for their therapeutic capabilities. Azadirachta indica (Neem) is widely recognized for its medicinal properties, including antibacterial, antifungal, an…

Review Article

Review
An Insight into the Therapeutic Value of Dillenia indica Linn: Phytochemical and Pharmacological Aspects
Salema Khatun, Saikat Sen
pp. 689–696 · DOI: 10.5530/pres.20252088 · Published Jul-Sep 2025
Dillenia indica Linn. is an evergreen tree belonging to the Dilleniaceae family, primarily found in the Himalayan and sub-Himalayan areas. The fruits of this plant are sour and are used as flavouring agents in cuisine. T…
Review
Natural Marine Species Bioactive Compounds and their Ethnopharmacological Approach from Ecological Biodiversity: Sustainable Therapeutic Properties
Paramita Ganguly, Puja Saha, Sandip Chatterjee, Prangya Paramita Pati
pp. 697–706 · DOI: 10.5530/pres.20252162 · Published Jul-Sep 2025
Marine ecosystems are a rich source of bioactive compounds, offering immense potential for therapeutic applications. Research studies from pubmed, Google scholar, Science direct, databases provided derived from diverse o…
Review
In silico Insights Into the Medicinal Potential of Phyllanthus amarus: Phytoconstituents and Therapeutic Applications
Ayushi Varshney, Pawan Kumar Gupta, Prashant Kumar, Shashi Bhooshan Tiwari
pp. 707–718 · DOI: 10.5530/pres.20252168 · Published Jul-Sep 2025
Phyllanthus amarus is a globally distributed herb. Over the 3000 years, it has been used as traditional medicine. This plant is articulated in different languages differently like in Hindi- Bhuyiavla, Jangli amla, Marath…
Review
Exploring the Potential of Anti-Diabetic Medicinal Plants and Phytocompounds
Gaurav Sarsodia, Raghvendra Dubey
pp. 719–727 · DOI: 10.5530/pres.20252175 · Published Jul-Sep 2025
Diabetes mellitus is a long-term metabolic disease that prolonged hyperglycemia can cause serious side effects that impact several organs and systems, such as peripheral neuropathy, retinopathy, and nephropathy. While in…
Review
Extraction and Quantification of Allicin: A Bioactive Component of Allium sativum
Dhanya B. Sen, Deven K. Parmar, Ashim Kumar Sen, Rajesh A. Maheshwari, Aarti S. Zanwar, Krupa Joshi, Shaileshkumar K. Koradia
pp. 728–739 · DOI: 10.5530/pres.20252211 · Published Jul-Sep 2025
Allicin, a bioactive compound found in garlic, exhibits remarkable pharmacological properties such as antimicrobial, antioxidant, and anticancer effects. Its therapeutic potential has garnered substantial attention, lead…
Review
Aflatoxin: A Prevalent Toxin in the Demesne of Existence
Aishik Banerjee, Arup Ghosh, Amartya Nandi, Deyasini Saha, Santosh Kumar Sahoo, Amit Kundu, Revu Baby Nalanda, Naresh Panigrahi, Partha Roy, Sumanta Mondal
pp. 740–754 · DOI: 10.5530/pres.20252183 · Published Jul-Sep 2025
Aflatoxin, a mycotoxin origin from food-borne microbes, poses a significant and remarkable risk to the safety and integrity of food. Mycotoxin-producing fungi can infect goods intended for human and animal consumption, i…
Review
Flavonoids: A Class of Polyphenols with Diverse Anti-inflammatory Activities and Mechanisms
Divya Jashvantkumar Kanojiya, Maitri Mahant, Sweta Besh, Sarika Parekh, Ghanshyam Parmar
pp. 755–768 · DOI: 10.5530/pres.20252237 · Published Jul-Sep 2025
The impact of our dietary choices on our overall well-being is widely recognized in the field of nutrition. The influence of diet on human metabolism is widely recognized, by the consumption of an abundance of fresh frui…
Review
Phytochemical Profile and Pharmacological Insights of Anisomeles malabarica Leaf Extracts: A Comprehensive Review
P Madhivardhana., E Kiranvikas., Z Ziya Huq Khan., S Mangal Raj.
pp. 769–777 · DOI: 10.5530/pres.20252254 · Published Jul-Sep 2025
Anisomeles malabarica, a medicinal plant native to India and Southeast Asia, has been traditionally used to treat various health issues, including fever, wounds, respiratory, and digestive disorders. This review provides…
Review
Phytochemical and Therapeutic Potential of Wrightia tinctoria R. Br: A Comprehensive Review
Sakthiganapathi Meenachisundaram, Kamesh Sendhil Murugan, Hema Munusamy, Shameera Banu Kafar Sharieff
pp. 778–787 · DOI: 10.5530/pres.20252245 · Published Jul-Sep 2025
Wrightia tinctoria, also referred to as vettpalai/indrajava, is an evergreen herbal tree belonging to the Apocynaceae family, found in India and the Southeast Asian region. Revered in ancient medical systems such as Ayur…
Review
Phytoflavonoids-A Future Perspective for the Therapeutic Potential of Alzheimer’s Disease
Karthigadevi Kamalakannan, Shanmuganathan Seetharaman, Anbazhagan Sockalingam, K Reeta VijayaRani, Kavimani Subramanian
pp. 788–795 · DOI: 10.5530/pres.20252213 · Published Jul-Sep 2025
Millions of people suffer from the neurodegenerative diseases like Alzheimer's Disease (AD) worldwide. Due to their complex pathology, no effective pharmacological treatment has been found to date, despite extensive rese…
Review
Ancient Pharmacognosy Book by Karmapa (1319)
Tsetsegdari Tumenbat, Selenge Erdenechimeg, Menghewulijii, Baoyintu, Bold Sharav, Tudevdagva Lkhagvadorj
pp. 796–800 · DOI: 10.5530/pres.20252212 · Published Jul-Sep 2025
Background Over the past 30 years, dozens of ancient and under-researched medical scriptures have been discovered, including a few medicinal books written by Indian and Tibetan scholars and monks from the 8th and 14th ce…
Review
In vitro and Computational Studies of Compounds from Coleus amboinicus against Osteosarcoma
Archana Behera, Raeesha Rahman, Benjamin Vinodh Joshua, Iadalin Ryntathiang, Monisha Prasad, Mukesh Kumar Dharmalingam Jothinathan
pp. 997–1004 · DOI: 10.5530/pres.20252178 · Published Jul-Sep 2025
Background Osteosarcoma (OS) is among the most prevalent primary bone cancers, predominantly affecting children and adolescents. The average prevalent rate of osteosarcoma is 4.3 per million in males and 3.4 per million …