Volume 14, Issue 53

Pharmacognosy Magazine’s Performance in the Year 2017: A Report

K. K. Mueen Ahmed

pp. 1–2 · DOI: 10.4103/0973-1296.225674 · Published 2018

Sulforaphane salads

Ashok Kumar Tiwari

pp. 3–3 · DOI: 10.4103/0973-1296.225675 · Published 2018

Hypolipidemic Effect of Psidium guajava Leaf Extract against Hepatotoxicity in Rats

K. Vijayakumar, R. L. Rengarajan, R. Radhakrishnan, A. Vijaya Anand

pp. 4–8 · DOI: 10.4103/pm.pm_167_17 · Published 20 February 2018

Background: Plant‑based natural extracts cure several diseases in human. However, the extract of Psidium guajava leaf is not yet evaluated on changes of lipid profile in hepatic disease affected rats. Objective: The pres…

Demethoxycurcumin, a Natural Derivative of Curcumin Abrogates Rotenone-induced Dopamine Depletion and Motor Deficits by Its Antioxidative and Anti-inflammatory Properties in Parkinsonian Rats

Muthu Ramkumar, Srinivasagam Rajasankar, Veerapan Venkatesh Gobi, Udaiyappan Janakiraman, Thamilarasan Manivasagam, Arokiasamy Justin Thenmozhi, Musthafa Mohamed Essa, Ranganathan Chidambaram, Saravana Babu Chidambaram, Giles J. Guillemin

pp. 9–16 · DOI: 10.4103/pm.pm_113_17 · Published 20 February 2018

Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder (NDD) associated with the loss of dopaminergic neurons in the substantia nigra and subsequently has an effect on motor function and coordin…

Optimization of Microwave-assisted Extraction of Silymarin from Silybum marianum Straws by Response Surface Methodology and Quantification by High-Performance Liquid Chromatograph Method

Hong-Sheng Ruan, Hai-Feng Zhang, Kun Teng

pp. 22–26 · DOI: 10.4103/pm.pm_556_16 · Published 20 February 2018

Background: Silybum marianum, a member of the Aster family, is a well‑known Chinese herb and the source of a popular antioxidant that is extensively used in Asia. The abundant S. marianum straws are still underutilized a…

Ameliorative Effect of Camel’s Milk and Nigella Sativa Oil against Thioacetamide-induced Hepatorenal Damage in Rats

Aftab Ahmad, Fahad A. Al-Abbasi, Saida Sadath, Soad Shaker Ali, Mohammed F. Abuzinadah, Hani A. Alhadrami, Anwar Ali Mohammad Alghamdi, Ali H. Aseeri, Shah Alam Khan, Asif Husain

pp. 27–35 · DOI: 10.4103/pm.pm_132_17 · Published 20 February 2018

Background: Camel milk (CM) and Nigella sativa (NS) have been traditionally claimed to cure wide range of diseases and used as medicine in different part of world, particularly in Saudi Arabia. Several research studies h…

Modeling and Optimum Extraction of Multiple Bioactive Exopolysaccharide from an Endophytic Fungus of Crocus sativus L

Lu Wen, Yuan Xu, Qiqiu Wei, Wuhai Chen, Gang Chen

pp. 36–43 · DOI: 10.4103/pm.pm_96_17 · Published 20 February 2018

Background: Crocus sativus L. (saffron) is a scarce plant that has been used as food flavoring agent, coloring agent, and traditional herbal medicine. Methods: The bioactivity of exopolysaccharide (EPS) extracted from an…

Combined Antihypertensive Effect of Paeoniflorin Enriched Extract and Metoprolol in Spontaneously Hypertensive Rats

Bo Li, Zheng-Biao Yang, Shan-Shan Lei, Jie Su, Ze-Wu Jin, Su-Hong Chen, Gui-Yuan Lv

pp. 44–52 · DOI: 10.4103/pm.pm_483_16 · Published 20 February 2018

Background: Hypertension is a great global health challenge and it mostly requires drug combination therapy with the various advantages. Metoprolol (MP) and paeoniflorin are both commonly used for the treatment of hypert…

Evaluation of Antioxidant, Antimicrobial, and Antiurolithiatic Potential of Different Solvent Extracts of Aerva lanata Linn Flowers

Padma Charan Behera, Manik Ghosh

pp. 53–57 · DOI: 10.4103/pm.pm_60_17 · Published 20 February 2018

Introduction: Aerva lanata (Linn) of family Amaranthaceae is an important and commonly used plant for its medicinal and pharmacological properties and proving the traditional uses of flowers of A. lanata Linn. Objective:…

The Standardized Extract of Limonium tetragonum Alleviates Chronic Alcoholic Liver Injury in C57BL/6J Mice

Na-Hyun Kim, Jeong-Doo Heo, Jung-Rae Rho, Min Hye Yang, Eun Ju Jeong

pp. 58–63 · DOI: 10.4103/pm.pm_44_17 · Published 20 February 2018

Background: In traditional folk medicine, Limonium tetragonum is used in the treatment of uterine hemorrhage, tinnitus, and oligomenorrhea. Objective: This study aimed to identify the therapeutic effect of L. tetragonum …

Identification of Three Kinds of Citri Reticulatae Pericarpium Based on Deoxyribonucleic Acid Barcoding and High-performance Liquid Chromatography-diode Array Detection-electrospray Ionization/Mass Spectrometry/Mass Spectrometry Combined with Chemometric Analysis

Xiaoxue Yu, Yafeng Zhang, Dongmei Wang, Lin Jiang, Xinjun Xu

pp. 64–9 · DOI: 10.4103/pm.pm_581_16 · Published 20 February 2018

Background: Citri Reticulatae Pericarpium is the dried mature pericarp of Citrus reticulata Blanco which can be divided into “Chenpi” and “Guangchenpi.” “Guangchenpi” is the genuine Chinese medicinal material in Xinhui, …

Antibacterial Activity of Azadirachta indica, Pongamia pinnata, Psidium guajava, and Mangifera indica and their Mechanism of Action against Streptococcus mutans

Dikonketso Cathrine Bodiba, Preety Prasad, Ajay Srivastava, Brigdet Crampton, Namrita Sharan Lall

pp. 76–80 · DOI: 10.4103/pm.pm_102_17 · Published 20 February 2018

Background: Curative plants have reportedly been used to make chewing sticks/toothbrushes intended for the treatment of oral diseases. Objective: The in vitro antibacterial activities of Azadirachta indica, Pongamia pinn…

Rhynchophylline Downregulates Phosphorylated cAMP Response Element Binding Protein, Nuclear Receptor-related-1, and Brain-derived Neurotrophic Factor Expression in the Hippocampus of Ketamine-induced Conditioned Place Preference Rats

Youli Guo, Chaohua Luo, Genghong Tu, Chan Li, Yi Liu, Wei Liu, Ken Kin Lam Yung, Zhixian Mo

pp. 81–6 · DOI: 10.4103/pm.pm_90_17 · Published 20 February 2018

Background: Addiction to ketamine is becoming a serious public health issues, for which there exists no effective treatment. Rhynchophylline (Rhy) is an alkaloid extracted from certain Uncaria species that is well known …

Further Study of Influence of Panax notoginseng on Intestinal Absorption Characteristics of Triptolide and Tripterine in Rats with Tripterygium wilfordii

Yiqun Li, Benyong Zhang, Mengzhu Liu, Xinlong Zhang, Donglei Shi, Liwei Guo, Jinao Duan, Xueping Zhou, Huaxu Zhu, Qichun Zhang

pp. 95–102 · DOI: 10.4103/pm.pm_67_17 · Published 20 February 2018

Background: Tripterygium wilfordii (TW) is widely employed to treat rheumatoid arthritis and autoimmune disorders clinically, which, however, accompany with disturbing hepatotoxicity and nephrotoxicity. The previous rese…

Antioxidant and Hemolysis Protective Effects of Polyphenol-Rich Extract from Mulberry Fruits

Palanigounder Ganeshan Ajay Krishna, Thasma Raman Sivakumar, Chao Jin, Shao-Hui Li, Yu-Jie Weng, Juan Yin, Jun-Qiang Jia, Chu-Yan Wang, Zhong-Zheng Gui

pp. 103–9 · DOI: 10.4103/pm.pm_491_16 · Published 20 February 2018

Background: Mulberry fruits are a superior source of polyphenol, especially anthocyanins that contribute potentially to the beneficial effects which include reducing the risk of cardiovascular diseases and cancers with a…

Capsaicin Reverses the Inhibitory Effect of Licochalcone A/β-Arbutin on Tyrosinase Expression in B16 Mouse Melanoma Cells

Jun-Hui Hong, Huo-Ji Chen, Shi-Jian Xiang, Si-Wei Cao, Bai-Chao An, Shi-Fa Ruan, Bin Zhang, Li-Dong Weng, Hong-Xia Zhu, Qiang Liu

pp. 110–5 · DOI: 10.4103/pm.pm_103_17 · Published 20 February 2018

Introduction: Melanin is synthesized by melanocytes, which are located in the basal layer of the skin. After synthesis, melanin is further deposited on the surface of the skin to form black spots or chloasma. Tyrosinase …

Cordyceps militaris Fraction Induces Apoptosis and G2/M Arrest via c-Jun N-Terminal Kinase Signaling Pathway in Oral Squamous Carcinoma KB Cells

Wangshi Xie, Zhang Zhang, Liyan Song, Chunhua Huang, Zhongyi Guo, Xianjing Hu, Sixue Bi, Rongmin Yu

pp. 116–23 · DOI: 10.4103/pm.pm_63_17 · Published 20 February 2018

Background: Cordyceps militaris fraction (CMF) has been shown to possess in vitro antitumor activity against human chronic myeloid leukemia K562 cells in our previous research. Materials and Methods: The in vitro inhibit…

Rhubarb Attenuates Cerebral Edema via Inhibition of the Extracellular Signal-regulated Kinase Pathway Following Traumatic Brain Injury in Rats

Zhaoyu Yang, Rong Fan, Peng Sun, Hanjin Cui, Weijun Peng, Jiekun Luo, Chunhu Zhang, Xingui Xiong, Wei Huang, Wei Liu

pp. 134–9 · DOI: 10.4103/pm.pm_218_17 · Published 20 February 2018

Background: Rhubarb is a traditional Chinese medicine for treating traumatic brain injury (TBI). Purpose: The purpose of this study is to elucidate the potential mechanism of rhubarb by suppressing extracellular signal-r…

Optimal Conditions for Decocting Later of Menthae Herba Eungyo-san (EGS) is a KM formula composed of nine herbal medicines:

Forsythiae Fructus, Lonicerae Flos, Platycodonis Radix, Menthae Herba

pp. 17–21 · DOI: 10.4103/pm.pm_97_17 · Published 20 February 2018

Background: “Decocting later” is important procedure for the extraction of herbal medicines containing volatile compounds. Objective: This study was performed to investigate optimal conditions for “Decocting later” of Me…

Quantitative Determination of Bioactive Constituents in Noni Juice by High‑performance Liquid Chromatography with Electrospray Ionization Triple Quadrupole Mass Spectrometry

Yongqiu Yan, Yu Lu, Shiping Jiang, Yu Jiang, Yingpeng Tong, Limin Zuo, Jun Yang, Feng Gong, Ling Zhang, Ping Wang

pp. 70–75 · DOI: 10.4103/pm.pm_74_17 · Published 20 February 2018

Background: Noni juice has been extensively used as folk medicine for the treatment of arthritis, infections, analgesic, colds, cancers, and diabetes by Polynesians for many years. Due to the lack of standard scientific …

Novel Method of Preparation and Activity Research on Arctigenin from Fructus Arctii

Enbo Cai, Jiahong Han, Limin Yang, Weiyuan Zhang, Yan Zhao, Qiulian Chen, Meng Guo, Xinhong He

pp. 87–94 · DOI: 10.4103/pm.pm_514_16 · Published 20 February 2018

Background: Arctigenin has many pharmacological activities with clinical significance and is derived from Arctium lappa L. However, the present extraction method is inefficient and does not have meaningful industrial pro…

Computational Tool for Immunotoxic Assessment of Pyrethroids toward Adaptive Immune Cell Receptors

Anoop Kumar, Padma Charan Behera, Naresh Kumar Rangra, Suddhasattya Dey, Kamal Kant

pp. 124–128 · DOI: 10.4103/pm.pm_62_17 · Published 20 February 2018

Background: Pyrethroids have prominently known for their insecticidal actions worldwide, but recent reports as anticancer and antiviral applications gained a lot of interest to further understand their safety and immunot…

Determination of Eupatilin in Folium artemisiae Argyi and Its Inhibitory Effect on Hepatoma Cells

Rui Liu, Jin Zhao, Ke He, Xiaodong Zhang, Liang Chang, Guoan Xiang

pp. 129–133 · DOI: 10.4103/pm.pm_472_16 · Published 20 February 2018

Aim: The aim of this study is to establish a method for determination of eupatilin in Folium artemisiae Argyi and observe the inhibitory effect of Folium artemisiae Argyi extract on human hepatoma SMMC‑7721 cells. Method…