Volume 15, Issue 66s

Original Article

1. Article

   Inhibitory Effects of Fermented Soybean Tempeh on the Anti‑Adhesive Properties of Actinomyces viscosus and Plaque Growth in vitro

   Allimalar Sathiaseelan, Chong Seng Shit, Tsun‑Thai Chai

   pp. S371–S376 · DOI: 10.4103/pm.pm_29_19 · Published 28 November 2019

   Objective: Here, we investigated the efficacy of tempeh HXF on other cariogenic virulence traits of A. viscosus such as adhesive properties, acid production, and plaque growth. Materials and Methods: Anti adhesion of HXF…

2. Article

   Selection of Suitable Reference Genes for Reverse Transcription‑quantitative Polymerase Chain Reaction Normalization in Artemisia annua L. Plants at Different Stages of Growth and Development

   Javed Ahmad, Nazima Nasrullah, Naved Quadri, Umara Nissar, Shashi Kumar, Malik Zainul Abdin

   pp. S377–S385 · DOI: 10.4103/pm.pm_600_18 · Published 28 November 2019

   Objectives: Our main aim for this study was to select the suitable reference gene for the normalization of reverse transcription‑quantitative polymerase chain reaction ( Reverse transcription RT‑qPCR) data in different t…

3. Article

   Modulation of Sodium Arsenite-Induced Toxicity in Mice by Ethanolic Seed Extract of Trigonella foenum graecum

   Surjyo Jyoti Biswas, Goutam Ghosh, Ved Prakash Dubey

   pp. S386–S395 · DOI: 10.4103/pm.pm_518_18 · Published 28 November 2019

   Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> L. is a well-known medicinal plant used in traditional medicine for bone healing. Objective: The pres…

4. Article

   Exploration of Antioxidant Capacity of Extracts of Perna viridis, a Marine Bivalve

   Venkateskumar Krishnamoorthy, Leow Yu Chuen, Vengadan Sivayogi, Sathasivam Kathiresan, Mohd Baidi Bahari, Gunasunderi Raju, Subramani Parasuraman

   pp. S402–S409 · DOI: 10.4103/pm.pm_301_19 · Published 28 November 2019

   Background: The biopotential of Malaysian green mussels (Perna viridis) has not been fully explored. The aim of the study is to screen the antioxidant capacity of extracts of Malaysian green mussels. Materials and Method…

5. Article

   Statistical Approach towards Optimization of Extraction Process of Karanjin from Pongamia pinnata Seeds

   Sartaj Akhtar Ansari, Lubna Abidin, Tinku Gupta, Mohd. Mujeeb, Aftab Ahmad, Varish Ahmad, Showkat Rasool Mir

   pp. S419–S425 · DOI: 10.4103/pm.pm_609_18 · Published 28 November 2019

   Objective: Use of Box–Behnken design for optimization of extraction of karanjin from P. pinnata seeds. Materials and Methods: Design expert software was used for optimization purpose. Extraction temperature, extraction t…

6. Article

   Metabolic Profile Elucidation of Ventilago calyculata Aqueous Extract Attenuating Sequelae of Aspirin Retarded Wound Healing

   Shweta Kumar, Rajesh Singh Pawar, Deepti Jain

   pp. S426–S432 · DOI: 10.4103/pm.pm_131_19 · Published 28 November 2019

   Objective: The objective of this work was to test the potential of formulations prepared from the extracts of V. calyculata against aspirin‑retarded wound healing in rats and investigate the probable mechanism of action.…

7. Article

   Ameliorative Potential of a Traditionally Used Plant Fraxinus micrantha against Oxidative Stress and Paracetamol‑Induced Hepatotoxicity

   Hasandeep Singh, Sarabjit Kaur, Saroj Arora, Balbir Singh

   pp. S433–S439 · DOI: 10.4103/pm.pm_236_19 · Published 28 November 2019

   Objective: The objective of the present study is to investigate the hepatoprotective potential of traditionally used plant Fraxinus micrantha against paracetamol (PCM)‑induced hepatotoxicity in rats. Methods: Hepatotoxic…

8. Article

   Antithrombocytopenic Potential of Bioactivity Guided Fractions of Traditionally Used Psidium guajava Linn. Leaves in Busulfan Induced‑Thrombocytopenic Rats

   Adil Ahmad, Mohammad Ibrahim, Karishma Chester, Washim Khan, Sayeed Ahmad, S. H. Ansari

   pp. S440–S448 · DOI: 10.4103/pm.pm_608_18 · Published 28 November 2019

   Background: Psidium guajava L. (family: Myrtaceae) is a traditionally used medicinal plant and possesses various therapeutic properties. This study was aimed to explore the antithrombocytopenic potential of bioactive fra…

9. Article

   The Cytoprotective Benefits of a Turmeric, Quercetin, and Rosemary Blend through Activation of the Oxidative Stress Pathway

   Arun Rajgopal, Samantha J. Roloff, Charlie R. Burns, David J. Fast, Jeffrey D. Scholten

   pp. S449–S454 · DOI: 10.4103/pm.pm_556_18 · Published 28 November 2019

   Objective: The objective of the study is to determine whether a natural product blend of turmeric, pagoda tree seed pod (quercetin), and rosemary (TQR) extracts can protect human liver cells from oxidative stress‑induced…

10. Article

    Antidiarrheal Potential of Eriosema chinense Vogel. against Enteropathogenic Escherichia coli‑Induced Infectious Diarrhea

    Komal M. Parmar, Jayshri R. Hirudkar, Dhiraj S. Bhagwat, Satyendra Kuldip Prasad

    pp. S455–S461 · DOI: 10.4103/pm.pm_129_19 · Published 28 November 2019

    Objective: The objective of the study was to evaluate the potential of roots from E. chinense against enteropathogenic Escherichia coli (EPEC)‑induced infectious diarrhea. Materials and Methods: Ethanolic extract of E. c…

11. Article

    Evaluation of Diosgenin Content in Costus speciosus Germplasm Collected from Eastern Ghats of India and Identification of Elite Chemotypes

    Akanksha Srivastava, Manish Kumar, Ankita Misra, Pushpendra Kumar Shukla, Pawan Kumar Agrawal

    pp. S462–S467 · DOI: 10.4103/pm.pm_72_19 · Published 28 November 2019

    Objective: The identification of elite chemotypes of C. speciosus (Rhizome) through high‑performance thin‑layer chromatography (HPTLC) from the Eastern Ghats (India). Materials and Methods: A validated HPTLC method for t…

12. Article

    Neuroprotective Efficacy of Polyphenols of Marine Brown Macroalga Ecklonia cava in Diabetic Peripheral Neuropathy

    Suman Samaddar, Raju Koneri

    pp. S468–S475 · DOI: 10.4103/pm.pm_212_19 · Published 28 November 2019

    Objectives: In this study, the neuroprotective effect of polyphenols isolated from the brown marine macroalga Ecklonia cava (EC) was evaluated in experimental diabetic peripheral neuropathy (DPN). Materials and Methods: …

13. Article

    Evaluation of Lipotropic Effect of Herbal Formulation on Hepatic Fat Accumulation in Rats Fed with Methionine-Choline Deficient Diet

    Prasanna Raja Chandrasekaran, Sasikumar Murugan, Edwin Jothie Richard, Bharathi Bethapudi, Divya Purusothaman, Chandrasekaran Chinampudur Velusami, Prashanth D’Souza, Deepak Mundkinajeddu, Muralidhar S. Talkad

    pp. S476–S482 · DOI: 10.4103/pm.pm_111_19 · Published 28 November 2019

    Objective: To investigate the lipotropic activity of the proprietary herbal formulation (PHF) containing Acacia nilotica and Curcuma longa. Materials and Methods: Fatty liver disease was induced in Wistar rats by feeding…

14. Article

    Dioscorea villosa Leaf Extract Enhances in vitro Wound Healing and Expression of Extra Cellular Matrix Factors Transforming Growth Factor‑Beta 1 and Collagen‑1 in L929 Cell Lines

    Murad Alsawalha, Abeer Mohammed Al‑Subaie, Reem Yousuf Al‑Jindan, Srinivasa Rao Bolla, Mohammed Salahuddin, Vishnu Priya Veeraraghavan, Dwaipayan Sen, Janardhana Papayya Balakrishna, Padma Kanchi Ravi, Joel Palpath Joseph, Aruthra Arumugam Pillai, Shiva Shankar Reddy Gollapalli, Shonima Pala, Fajre Pengateeri, George Dominic, Surapaneni Krishna Mohan

    pp. S483–S494 · DOI: 10.4103/pm.pm_81_19 · Published 28 November 2019

    Background: Easy availability, relatively low cost with fewer side effects, has made the herbal extracts/fractions/pure compounds as prominent source of medicinally important molecules. Dioscorea villosa L. commonly know…

15. Article

    Curcumin Vasorelaxation in Uterine Artery of Goat (Capra hircus) is Mediated by Differential Activation of Nitric Oxide, Prostaglandin I2, Soluble Guanylyl Cyclase, and Gap Junction Communication

    Harithalakshmi Jandhyam, Subas Chandra Parija

    pp. S495–S501 · DOI: 10.4103/pm.pm_188_19 · Published 28 November 2019

    Background: Curcumin is a principal active constituent of Curcuma longa and has potential therapeutic application in various disease states. In this study, we investigated the mechanism of vasorelaxatory effects of curcu…

16. Article

    Inhibition of Key Digestive Enzymes Involved in Glucose Metabolism by Biosynthesized Zinc Oxide Nanoparticles from Syzygium cumini (L.): An in vitro and in silico Approach

    J. Arul Daniel, S. Asha Devi

    pp. S502–S509 · DOI: 10.4103/pm.pm_253_19 · Published 28 November 2019

    Objective: The aim of the study was to synthesize, characterize, and evaluate the antidiabetic effect of zinc oxide nanoparticles (ZnO NPs) from Syzygium cumini (SC). Materials and Methods: ZnO NPs were synthesized using…

17. Article

    Herniarin, a Natural Coumarin, Inhibits Mammary Carcinogenesis by Modulating Liver X

    Receptor‑α/β‑PI3K‑Akt‑Maf1 Pathway in Sprague‑Dawley Rats

    pp. S510–S519 · DOI: 10.4103/pm.pm_264_19 · Published 28 November 2019

    Objectives: Thus, this study was performed to assess the chemotherapeutic potential of herniarin (HER), a 7‑methoxycoumarin derivative against polycyclic aromatic hydrocarbon‑induced mammary cancer. Materials and Methods…

18. Article

    Cellular Protection Induced by Genistein in Mouse and its Antioxidant Capacity

    Rogelio Paniagua-Pérez, Susana Reyes-Cadena, Carlos Martínez-Canseco, Celia Reyes-Legorreta, Jesús Martínez-Castro, Eduardo O. Madrigal-Santillán, José A. Morales-González, José M. Cristóbal-Luna, Isela Álvarez-González, Eduardo Madrigal-Bujaidar

    pp. S520–S526 · DOI: 10.4103/pm.pm_78_19 · Published 28 November 2019

    Objective: The main objective of the study is to determine the capacity of GT to inhibit the genotoxic and cytotoxic damage induced by CP in mouse, as well as its immunostimulant ability and its capacity to scavenge free…

19. Article

    Kalanchoe blossfeldiana Extract Induces Cell Cycle Arrest and Necrosis in Human Cervical Cancer Cells

    Justyna Stefanowicz‑Hajduk, Magdalena Gucwa, Adam Hajduk, J. Renata Ochocka

    pp. S527–S537 · DOI: 10.4103/pm.pm_86_19 · Published 28 November 2019

    Objective: The objective of the study is to estimate the cytotoxic activity of KB on human cervical carcinoma (HeLa) cells and determine the mode of cell death. Materials and Methods: The cytotoxic activity of ethanolic …

20. Article

    SUNCA Standardized Extract from Helianthus annus L Exerts Enhanced Digestive Enzyme Activity and Subsides Obesity through Inhibition of C/EBP-α and PPAR-γ Expression Both in in vitro and in vivo Model

    K. Gouthamchandra, Sudeep HV, Amritharaj Amritharaj, Lingaraju H B, Shyam Prasad K

    pp. S538–S544 · DOI: 10.4103/pm.pm_204_19 · Published 28 November 2019

    Background: Helianthus annuus L. (sunflower) is well known for its edible oil, sunflower seed has been used as folk remedy for several diseases including cancer. Materials and Methods: In this study, SUNCA, a standardize…

21. Article

    Proanthocyanidins Rich Extract of Calligonum comosum Ameliorates Doxorubicin‑Induced Immunosuppression and Hepatorenal Toxicity

    Essam Abdel‑Sattar, Doaa H. Abdelhady, Emad W Ghazy, Walied Abdo, Zizy I. Elbialy, Mustafa Shukry, Engy Abdelhameed Mahrous, Sendker Jandirk

    pp. S545–S552 · DOI: 10.4103/pm.pm_670_18 · Published 28 November 2019