Volume 16, Issue 5S

Original Article

1. Article

   Embelin from Embelia ribes Ameliorates Oxidative Stress and Inflammation in High‑Fat Diet‑Fed Obese C57BL/6 Mice

   Priyanka Bansal, Uma Bhandari, Sayeed Ahmad

   pp. S443–S449 · DOI: 10.4103/pm.pm_77_20 · Published 30 November 2020

   Objectives: This study was designed to isolate and characterize embelin from Embelia ribes and further to assess its role in alleviating oxidative stress and chronic inflammation in the high‑fat diet (HFD) fed obese C57B…

2. Article

   Enhancement of Chlorogenic Content of the Eggplant Fruit with Eggplant Hydroxycinnamoyl CoA‑Quinate Transferase Gene via Novel Agroinfiltration Protocol

   Prashant Kaushik, Pankaj Kumar, Shashi Kumar

   pp. S450–S454 · DOI: 10.4103/pm.pm_537_19 · Published 30 November 2020

   Objective: The function of SmHQT is not well determined in the eggplant fruit, and the fruit agroinfiltration procedure is not standardized for eggplant. Materials and Methods: Here, the overexpression of SmHQT in the eg…

3. Article

   Effect of Plant Part, Extraction Method, and Harvest Time over Antioxidant Yield of Rubus coreanus

   Min Ju Lee, Ju Hee Nam, Jeong Ho Jeong, Il Rae Rho

   pp. S455–S461 · DOI: 10.4103/pm.pm_549_19 · Published 30 November 2020

   Objectives: We aimed to analyze the contents of five antioxidants in leaves and branches of R. coreanus using different extraction method. Materials and Methods: R. coreanus were cultivated at the research farm of the Gy…

4. Article

   Chromatographic Investigation of Phytoconstituents in Milk Yam (Ipomoea digitata L.) Tubers

   N. S. Sonia, Thomas George

   pp. S462–S466 · DOI: 10.4103/pm.pm_116_20 · Published 30 November 2020

   Objective: The present study is done with the aim of identifying the maturity stage of milk yam tuber containing maximum concentration of umbelliferone – a coumarin present in the tubers. Materials and Methods: Umbellife…

5. Article

   Rasam (South Indian Spice Soup) - Attenuates the Mammary Tumor Induction Magnitude of 7,12‑Dimethylbenz[a] anthracene in Sprague–Dawley Rats

   Muthu Kumaradoss Mohanmarugaraja, Agilandeswari Devarajan, Muthu Kumaradoss Kathiravan

   pp. S467–S473 · DOI: 10.4103/pm.pm_150_20 · Published 30 November 2020

   Objectives: Breast cancer seems to be more common in the younger age group. Considering the deviation of the younger group from the traditional food habits as one of the many reasons of breast cancer incidence, rasam was…

6. Article

   Herniarin, a Natural Coumarin Loaded Novel Targeted Plasmonic Silver Nanoparticles for Light Activated Chemo‑Photothermal Therapy in Preclinical Model of Breast Cancer

   Pritha Bose, Shakti P Pattanayak, Amiya Priyam

   pp. S474–S485 · DOI: 10.4103/pm.pm_223_20 · Published 30 November 2020

   Objectives: In this study we formulated novel pentagonal plasmonic silver nanoparticles as folate receptor targeted light responsive nano‑delivery platform for a potent coumarin derivative, Herniarin to improve its thera…

7. Article

   Method Development on Reverse‑Phase High‑Performance Liquid Chromatography for the Improvement of Routine Analysis of Flavonoids on Agricultural and Food Products

   Paranthaman Ramakrishnan, Chakkaravarthi Kamalanathan, Vidyalakshmi Rajagopal

   pp. S486–S491 · DOI: 10.4103/pm.pm_422_19 · Published 30 November 2020

   Objectives: The objective of this work was to investigate the effect of reversed‑phase high‑performance liquid chromatography conditions for the determination of flavonoids in the plant extract. Methods: The analytical c…

8. Article

   Effect of Vitex pinnata L. Leaf Extract on Estrogenic Activity and Lipid Profile in Ovariectomized Rats

   Wilawan Promprom, Wannachai Chatan, Phukphon Munglue

   pp. S492–S497 · DOI: 10.4103/pm.pm_443_19 · Published 30 November 2020

   Objectives: To compare the estrogenic activity and lipid profile of ethanol extracts of leaves of Vitex pinnata L. with 17 β‑estradiol in bilaterally ovariectomized (OVX) rats. Methods: Ethanol extracts were analyzed by …

9. Article

   In vitro Evaluation of Hydrilla verticillata for Anti‑Adipogenesis Activity on 3T3 L1 Cell Lines

   S. Pandi Prabha, S. Sadhana, C. Karthik, D. G. Caroline

   pp. S498–S505 · DOI: 10.4103/pm.pm_234_20 · Published 30 November 2020

   Background: Obesity is a metabolic disorder that has reached pandemic proportions worldwide. Phytol, a diterpene isoprenoid alcohol found as an integral part of chlorophyll of plants, algae, and guts of ruminant animals,…

10. Article

    Pueraria candollei var. mirifica‑Induced CYP1A1 and CYP1A2 Expression in Human Choriocarcinoma BeWo Cells

    Waranya Chatuphonprasert, Tharita Kitisripanya, Waraporn Putalun, Isabella Ellinger, Kanokwan Jarukamjorn

    pp. S506–S512 · DOI: 10.4103/pm.pm_164_20 · Published 30 November 2020

    Objectives: The objective of this study was to compare the effects of PM and the CYP1A inducer β‑naphthoflavone (BNF) on the expression of CYP1, aryl hydrocarbon receptor (AHR), AHR nuclear translocator (ARNT), and the t…

11. Article

    A Pentacyclic Triterpene from Lippia origanoides H.B.K and its Cytotoxic Activity

    Arvind Kumar, Elizabeth Quintero Rueda, Jairo Rene Martínez, Raquel Elvira Ocazionez, Elena E. Stashenko

    pp. S513–S516 · DOI: 10.4103/pm.pm_218_20 · Published 30 November 2020

    Objectives: The current study was designed to investigate the phytochemicals from the steam‑distilled residual biomass of thymol‑ and carvacrol‑rich L. origanoides chemotypes and to evaluate their in vitro cytotoxic acti…

12. Article

    Extraction and Volatile Compounds Profiling of the Bioactive Fraction of Monochoria hastata (L.) Solms

    Debabrata Misra, Manab Mandal, Narendra Nath Ghosh, Vivekananda Mandal

    pp. S517–S523 · DOI: 10.4103/pm.pm_386_19 · Published 30 November 2020

    Objectives: To evaluate the optimized extraction methods and solvents for antibacterial activity and their characterization by gas chromatography‑mass spectrometry (GC‑MS). Materials and Methods: Extractions from the aer…

13. Article

    Effect of Ethanolic Extract of Carica papaya Leaves and their Cytotoxicity and Apoptotic Potential in Human Ovarian Cancer Cell Lines‑ PA‑1

    Priyadurairaj Priyadurairaj, Palagati Rohith Kumar Reddy, Palaniyandi Thiruvanavukkarasu, Sindhu Rajesh, Suganya Karunakaran, Rajeswary Hari

    pp. S524–S530 · DOI: 10.4103/pm.pm_117_20 · Published 30 November 2020

    Background: The present study was aimed to evaluate the anti-inflammatory and analgesic activities of the methanolic extract of <em>Cissus quadrangularis</em> (MECQ) in experimental animal models. Materials and Methods: …

14. Article

    Germinated Seeds of Hordeum vulgare Target Extrinsic Pathway of Apoptosis in Triple‑Negative Breast Cancer Cells

    G. H. Akhil, Bibu John Kariyil, G. D. Akshatha, S.V. Vasudhar Bhatt, G. Dhanusha, Reni John

    pp. S531–S539 · DOI: 10.4103/pm.pm_123_20 · Published 30 November 2020

    Objectives: The present study aimed to evaluate the anticancer activity of methanol extract of germinated seeds of H. vulgare (MGHV) against MDA‑MB‑231 TNBC cells, quantify hordenine in MGHV, and derive the probable targ…

15. Article

    DNA Barcoding Markers to Identify Intraspecies Genetic Variations in Three Ecotypes of Abrus precatorius L.

    Srinivasan Marimuthu, G. P. Pratap, Goli Penchala Prasad, Shyam Baboo Prasad, Anupam Kumar Mangal, N. Srikanth

    pp. S540–S545 · DOI: 10.4103/pm.pm_23_20 · Published 30 November 2020

    Objectives: The present study aims to compare three different varieties of A. precatorius which includes the species of white, black, and red which are used to study DNA barcoding marker and phylogenetic analysis. Materi…

16. Article

    Anti‑Cancer Activity of Ethanolic Leaf Extract of Salvia officinalis against Oral Squamous Carcinoma Cells in vitro via Caspase Mediated Mitochondrial Apoptosis

    Prasanna Rajagopalan, Shadma Wahab, Ayed A. Dera, Harish C. Chandramoorthy, Safia Irfan, Ayyub Ali Patel, Shahabe Saquib Abullias, Gaffar Sarwar Zaman, Irfan Ahmad

    pp. S546–S552 · DOI: 10.4103/pm.pm_90_20 · Published 30 November 2020

    Aim: Need for novel agents that fight oral squamous cancer is on constant demand. The current study aims in the identification of active phytochemical ingredients from Salvia officinalis leaf extract (SOLE) and evaluatio…

17. Article

    Binding of Metronidazole to Enterococcus faecalis Homoserine Kinase: Binding Studies, Docking Studies, and Molecular Dynamics Simulation Studies

    Harpreet Singh, Satyajeet Das, Pramodkumar P Gupta, Sagar Batra, Richa Prakash, Vijay Kumar Srivastava, Anupam Jyoti, Vikas Gupta, S. L. Kothari, Sanket Kaushik

    pp. S553–S560 · DOI: 10.4103/pm.pm_99_20 · Published 30 November 2020

    Objective: Looking at the increasing number of infections caused by Ef, it is essential to develop alternative strategies to fight against Ef. In this regard, homoserine kinase (HSK) is an important enzyme of threonine b…

18. Article

    Effects of Artemisia judaica Essential Oil and Ethanolic Extract on Experimentally‑Induced Benign Prostatic Hyperplasia

    Bahaa Al‑Trad, Mazhar Al Zoubi, Mu’ath Migdady, Jamil Lahham, Alaa AA Aljabali, Malek Shehab, Sahar Alomari, Mahmoud A Al‑Qudah, Janti Qar, Riyadh Muhaidat, Ahmad El‑Oqlah, Murtaza M. Tambuwala

    pp. S561–S565 · DOI: 10.4103/pm.pm_216_20 · Published 30 November 2020

    Objectives: The present study aimed to address the effects of EO and EE on experimentally‑induced BPH in rats. Materials and Methods: Four experimental groups were assigned with six rats in each group, including the corn…

19. Article

    Protective Effect of Viburnum grandiflorum against Ultraviolet‑B Radiation‑induced Cellular and Molecular Changes in Human Epidermal Keratinocytes

    Hanjun Liu, Haixiu Zhang, Minyan Dang, Yukiat Lin, Hui Yan

    pp. S566–S572 · DOI: 10.4103/pm.pm_397_19 · Published 30 November 2020

    The aim of the present study was to evaluate the photoprotective potential of Viburnum grandiflorum (VG) against ultraviolet‑B radiation‑induced responses in HaCaT cells. The HaCaT cells were pretreated with VG prior ult…

20. Article

    Antioxidant Activity and Inhibitory Effect on Nitric Oxide Production of Rang Chuet (Thunbergia laurifolia Lindl.) Leaf Extracts in Lipopolysaccharide‑Stimulated BV2 Microglial Cells

    Nootchanat Mairuae, Poonlarp Cheepsunthorn, Benjaporn Buranrat

    pp. S573–S577 · DOI: 10.4103/pm.pm_44_20 · Published 30 November 2020

    Objectives: The aim of this study was to investigate the effects of Thunbergia laurifolia Lindl. or Rang Chuet (RC) extracts on reactive oxygen species (ROS) and nitric oxide (NO) production in lipopolysaccharide (LPS)‑a…