Volume 18, Issue 3

Jul-Sep 2026 · pp. 632–1102 · 42 articles

Volume: 18
Issue: 3
Published: Jul-Sep 2026
Pages: 632–1102
Articles: 42
Sections: 3
ISSN: ISSN: Print - 0976-4836, Online - 0974-8490
Journal: Pharmacogn. Res.

Original Article Case Report Review Article

In this issue

Original Article

Article
Phytochemical Evaluation and Anti-inflammatory Efficacy of Phenolic and Flavonoid Constituents in Euphorbia microphylla B. Heyne ex Roth.
Nitin Balasaheb Lonikar, Manisha Sureshkumar Sutare, Amar Ramrao Mane, Nandkishor Bhimashankar Bavage
pp. 1006–1017 · DOI: 10.5530/pres.20260299 · Published Jul-Sep 2026
Background Medicinal plants are natural sources of biochemical compounds with negligible side effects; Euphorbia microphylla is known for producing pharmacologically active compounds used in traditional medicine. Materia…
Article
Evaluation of the Nephroprotective Effects of Selected Aeginetia indica L. Extract Against Gadolinium-Induced Renal Toxicity
Ashish Sarkar, Subarna Mandal, Rabirajan Biswal, Arijit Chaudhuri, Biswajit Dash, Sandhya Suresh, Rekha Gupta, Nisha Devi
pp. 1018–1031 · DOI: 10.5530/pres.20260302 · Published Jul-Sep 2026
Background Gadolinium-Based Contrast Agents (GBCAs) are widely used in diagnostic imaging but are associated with nephrotoxicity, especially in patients with impaired renal function. Oxidative stress, inflammation, and t…
Article
Structure-Activity Relationship of Flavonoids as Antibacterial Agents: Insights from in vitro and in silico Evaluation
Rachael Ashok, Foram Patel, Darshee Baxi, Denni Mammen
pp. 1032–1047 · DOI: 10.5530/pres.20260304 · Published Jul-Sep 2026
Background Flavonoids, a large class of polyphenols, have wide structural diversity which can be exploited to design potential leads for treating bacterial infections. However, the effect of the functional groups present…
Article
Evaluation of in vitro Antioxidant, in vitro Cytotoxicity on HepG2 Cell line and Hepatoprotective Activity against Paracetamol Induced Hepatotoxicity in Rats of Piperonylic Acid
Venumadhuri Rageer, Juturu Mastanaiah
pp. 1048–1055 · DOI: 10.5530/pres.20260306 · Published Jul-Sep 2026
Background Excessive paracetamol use can cause liver damage, which is a major public concern. Pharmacological approaches are under investigation to avert such damage. The principal objective of the present investigation …
Article
Comprehensive Physico-chemical and HPTLC-Based Standardization of Devdarvyadi Churna: A Classical Ayurvedic Formulation
Rivanshi Ajaybhai Joshi, Manu Rajagopalaiah, Dixit Donga
pp. 1056–1063 · DOI: 10.5530/pres.20260307 · Published Jul-Sep 2026
Background Devdarvyadi Churna is a classical Ayurvedic polyherbal formulation described by Acharya Charaka for the management of Kaphaja Kasa (cough of Kapha origin). It comprises Devadaru, Haritaki, Musta, Pippali, and …
Article
Pharmacognostical and Physicochemical Analysis of Stem Bark of Punica granatum L.
Amit Rishi, Harpreet Singh
pp. 1064–1075 · DOI: 10.5530/pres.20260258 · Published Jul-Sep 2026
Background Punica granatum L. (Lythraceae), or pomegranate, is a vital medicinal plant in traditional systems like Ayurveda and Unani. Its stem bark is particularly valued for its healing powers and richness in tannins, …
Article
Preliminary Phytochemical Screening and Pharmacological Evaluation of Mundulea sericea for Antidiabetic Activity
Rupali Balasaheb Kote, Dhananjay Macchindra Patil
pp. 1094–1102 · DOI: 10.5530/pres.20260136 · Published Jul-Sep 2026
Background Mundulea sericea is a lesser-studied medicinal plant with potential pharmacological applications. Despite its traditional use, limited scientific reports are available on its phytochemical constituents and ant…
Article
Synergistic Effects of Betanin and Thymoquinone Combinations on Periodontal Ligament Cell Proliferation and Migration
Varun Senthil Kumar, Karthik Ganesh Mohanraj, Taniya Mary Martin, Meenakshi Sundaram Kishore Kumar
pp. 733–740 · DOI: 10.5530/pres.20260094 · Published Jul-Sep 2026
Background Natural polyphenols such as Betanin and Thymoquinone have demonstrated individual therapeutic potential in wound healing, antioxidant activity, and anti-inflammatory responses. However, their combinatorial eff…
Article
Structural Elucidation of Bioactive Constituents Isolated from Areca catechu L.
Kavita Nilesh Yadav, Prasad Vijay Kadam, Abhijit Sampatrao Karanje, Prachi Ashokrao Halburge, Yogesh Bapurao Kharat, Gautam Adinath Bade
pp. 741–749 · DOI: 10.5530/pres.20260095 · Published Jul-Sep 2026
Background Areca catechu is a significant tropical palm, primarily cultivated for its nut, which holds traditional, medicinal, and socio-cultural importance across Asia. Objectives This current study show the isolation a…
Article
Chemical Profiling of Mangifera indica Leaf and Mucuna pruriens Seed Extracts: A Phytochemical and Gas Chromatography-Mass Spectrometry-Based Study
Mohamad Qutboddin, Syed Sagheer Ahmed, Pooja Rangenahalli Chidananda Murthy, Mohammad Ali, Bharathi Doddla Raghunathanaidu
pp. 750–763 · DOI: 10.5530/pres.20260103 · Published Jul-Sep 2026
Background Medicinal plants remain an essential source of therapeutic agents due to their abundant phytochemicals and pharmacological attributes. Mangifera indica (mango) leaves and Mucuna pruriens (velvet bean) seeds ar…
Article
Free Radical Scavenging Activity and its Embryonic Toxicology Effect of Justicia betonica Leaves Mediated Iron Oxide Nanoparticles
Sulochana Govindharaj, Kaavya Shanmuga Sundaram, Rajeshkumar Shanmugam, Yuvabalaji Sankaran
pp. 764–770 · DOI: 10.5530/pres.20260116 · Published Jul-Sep 2026
Background An important milestone in the use of nanoscience and nanotechnology is the development of a dependable and environmentally acceptable green method for the manufacture of magnetic nanoparticles. Numerous biomed…
Article
Investigation of Pharmacognostic and Phytochemical Profiling of Cordia macleodii Hook.
Khemkaran Ahirwar, Junaid Khan
pp. 771–778 · DOI: 10.5530/pres.20260145 · Published Apr-Jun 2026
Aim Cordia macleodii Hook., a medium-sized polygamous tree native to parts of India, holds significant promise in traditional medicine. Despite its ethnobotanical relevance, comprehensive pharmacognostic and phytochemica…
Article
Betanin and Resveratrol as Dual Modulators of Apoptotic Signaling in Oral (KB) and Osteosarcoma (143B) Cells
Mampi Payra, Meenakshi Sundaram Kishore Kumar, Taniya Mary Martin, Jayalakshmi Somasundaram, Pallabi Ghosh
pp. 779–787 · DOI: 10.5530/pres.20260137 · Published Jul-Sep 2026
Background Oral Squamous Cell Carcinoma (OSCC) is characterised by its ability to evade apoptosis, contributing to therapeutic resistance and poor clinical outcomes. Natural compounds such as betanin and resveratrol have…
Article
Recent Advances in Controlling of Urinary Tract Infecting Pathogens Using Metal Nanoparticles and Nanocomposites
Bhakkia Rani Rajendran, Rajeshkumar Shanmugam, Sulochana Govindharaj
pp. 801–814 · DOI: 10.5530/pres.20260190 · Published Jul-Sep 2026
Urinary Tract Infections (UTIs) are among the most prevalent bacterial infections worldwide, often complicated by antibiotic resistance, biofilm formation, and high recurrence rates. Conventional treatment strategies are…
Article
Berberine Chloride Phytosomes: Development and Evaluation of a Novel Phospholipid Based Delivery System
Daksha Attarde, Neeraj Lohagaonkar, Anushka Deore, Bhagyashree Borde
pp. 815–821 · DOI: 10.5530/pres.20260205 · Published Jul-Sep 2026
Background Phytosomes are an advanced drug delivery system designed to improve the solubility, stability, and bioavailability of plant-based compounds. Objectives This study aimed to formulate and characterize berberine …
Article
Antimicrobial, Anti-inflammatory and Cytotoxicity Evaluation of a Novel Formulated Nano-Colloidal Mouthwash: An in vitro Study
Varun Batra, Balaji Ganesh Subramanian
pp. 822–828 · DOI: 10.5530/pres.20260191 · Published Jul-Sep 2026
Background Adjunctive mouthwashes are widely used in periodontal care to control plaque and gingival inflammation. Conventional agents such as chlorhexidine are effective but associated with adverse effects including too…
Article
Combining Experimental and Computational Approaches to Elucidate the Anti-T2DM Potential of Eriobotrya japonica Flower: In vitro Enzyme Inhibition, Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation
Hanhua Wang, Sisi Zeng, Yanyue Wang
pp. 829–842 · DOI: 10.5530/pres.20260221 · Published Jul-Sep 2026
Objectives To investigate the anti-T2DM potential and mechanism of Eriobotrya japonica (loquat) flower using an integrated approach combining in vitro assays, network pharmacology, molecular docking, and Molecular Dynami…
Article
Evaluating the Curative Potential of Vilangin for Parkinson’s Disease Treatment through in vitro and in silico Approach
Nivetha Rajendiran, Senthilkumar Sivanesan, Eswaran Rajkumar, Vimal Sugumar, Radhakrishnan Narayanaswamy, Ethirajan Sukumar, Rajagopalan Vijayaraghavan, Jayakumar Rajadas
pp. 843–854 · DOI: 10.5530/pres.20260225 · Published Jul-Sep 2026
Introduction Parkinson’s Disease (PD) is due to gradual deterioration of the aging brain and motor functions. The rising prevalence of PD suggests the need for better therapies to slow down or halt its progression. Our K…
Article
Comparative Pharmacognostic Profiling of Three Major Millets
Neethu Kannan Bhagyanathan, Ghanthi Kumar Subramanian, Natarajan Moorthy, Reena Viswan Lilly
pp. 855–862 · DOI: 10.5530/pres.20260229 · Published Jul-Sep 2026
Background Millets are small-grained nutri-cereals of the family Poaceae and are increasingly recognized for their nutritional and functional significance. Establishing standardized quality parameters is essential for th…
Article
Characterization and Therapeutic Potential of Marine-Derived Loligo duvauceli Ink Powder
Sekar Ragavi, Pechimuthu Karpagam, Kunnathur Murugesan Sakthivel, Kumar Pavithra
pp. 863–869 · DOI: 10.5530/pres.20260231 · Published Jul-Sep 2026
Background This research work focuses on the bioactive components of squid (Loligo duvauceli) ink, a naturally occurring marine fluid that is potentially defensive and has therapeutic qualities. This study investigates t…
Article
Exploring Wide Range of Antimicrobial, Antioxidant and Cytotoxicity Profile of Acacia chundra. (Roxb) DC (Kheri Plant)
Rahul More, Anuradha Ingle, Shweta Gaikwad, Shradda Ghatol, Mahesh Karale, Nagnath Phartale, Kailash Sontakke, Govind Sanap, Shreyas Mahurkar, Yuvaraj Sarnikar, Santosh Chobe
pp. 870–882 · DOI: 10.5530/pres.20260237 · Published Jul-Sep 2026
Background Acacia chundra (Roxb.) DC (AC) is a xerophytic habitat plant. It is one of the important medicinal plants found in Asia, India and in the Indian Ocean area. In the present study, phytochemical analysis, antimi…
Article
LC-MS-Based Phytochemical Profiling of Priyangvadi choorna and its Correlation with Hemostatic Activity
Adithya Anil Bams, Santosh Yallappa Mudakappagol, Raj Joshi
pp. 883–889 · DOI: 10.5530/pres.20260260 · Published Jul-Sep 2026
Background Priyangvadi Churna is a traditional indigenous Ayurvedic Polyherbal formulation explained in the treatment of bleeding disorders (Raktapitta) by Yogaratnakar. In spite of its renowned efficacy in standard Ayur…
Article
Comparative Assessment of the Therapeutic Efficacy of Selected Pashanbheda Plants
Archna Sahay, Pritee Chunarkar Patil, Vaishnavi Jadhav, Saba Shaikh, Riya Nair, Sanskruti Patil, Gouri Chorghe, Akshay Malusare, Aboli Shelake, Shamim Shaikh
pp. 890–898 · DOI: 10.5530/pres.20260242 · Published Jul-Sep 2026
Background The process of formation or appearance of a urinary stone anywhere in the renal tract is known as urolithiasis. Several plants are used and sold as ‘Pashanbheda' in different parts of the world. In this work w…
Article
Targeting Oral Biofilms and Inducing Apoptosis in Oral Cancer Cells: Mechanistic Insights of Hamamelitannin-Coated Zinc Oxide Nanoparticles through BCl-2/BAX/P53 Pathway
Thangaraj Aravindan, Maria Mathew, Taniya Mary Martin, Meenakshi Sundaram Kishore Kumar
pp. 899–911 · DOI: 10.5530/pres.20260271 · Published Jul-Sep 2026
Objectives Dental pathogens are major contributions to problems with oral health such infections, gum disease, and tooth decay. There is also growing evidence connecting these infections to the development and course of …
Article
Comprehensive Nutritional Profiling and Therapeutic Evaluation of Ten Ayurveda-Based Anti-Rheumatic Dietary Preparations
Swasthik, Sandeep Subash Sagare, Suketha Kumari
pp. 912–918 · DOI: 10.5530/pres.20260265 · Published Jul-Sep 2026
Background Rheumatic conditions are present in millions of people all over the world, and more attention is directed towards Ayurvedic dietary therapies that should be used as a supplement to conventional treatment metho…
Article
Anacardic Acid Ameliorates Anti-Inflammatory and Antioxidant Signaling Pathways in Human Hepatocellular Carcinoma HepG2 ARE Cells
Sangita Panda, Enketeswara Subudhi, Anand Bhaskar, Siddharth Modi, Dilip Mehta, Sujit Nair
pp. 919–931 · DOI: 10.5530/pres.20260273 · Published Jul-Sep 2026
Background Anacardic Acid (AA) is derived from cashew kernel shells and cashew apples and recognized for its extensive pharmacological properties, which include significant antitumor activity. Previous studies have estab…
Article
Mapping the Anti-Anaemic Signaling Landscape of Rajanyadi Churna Using Network Pharmacology-Driven Molecular Docking
Savita Sunadholi, Azizahmed I Arbar, Isha Kandwal
pp. 932–943 · DOI: 10.5530/pres.20260279 · Published Jul-Sep 2026
Background Anaemia is a multifactorial hematological disorder influenced by impaired erythropoiesis, chronic inflammation, oxidative stress, and disturbed iron metabolism. Rajanyadi Churna is a well-known classical Ayurv…
Article
Pharmacognostic, Nutritional, Antioxidant, Anti-diarrheal and Vasoconstrictive Potential of Solanum melongena L. Leaf and Stem: In vitro and in silico Study
Asad Saleem Sial, Muhammad Mohtasheemul-Hasan, Khizar Abbas, Ambreen Aleem, Jahanzeb Mudassir, Iqra Islam, Imran Ahmad, Rizwana Manzoor, Usman Javaid, Adeel Usman, Syed Zia Ul Hasnain
pp. 944–962 · DOI: 10.5530/pres.20260283 · Published Jul-Sep 2026
Background/Purpose Eggplant is one of the top ten vegetables with antioxidant capacity, traditionally used to cure gastrointestinal, cardiac, diabetic, and neurotoxic conditions. The purpose of the research is to carry o…
Article
Promising Source of Phytochemicals, Antioxidants, and Antibacterial Actions of Pomegranate (Punica granatum L.) Juice Extracts Using Different Solvents
C Reddy Prasad, D Santhoshi Roopa, Mahesh B Modhol, Senthilkumar Sivanesan, Thirunavukkarasu Jayaraman
pp. 963–970 · DOI: 10.5530/pres.20260291 · Published Jul-Sep 2026
Background The highly nutritious pomegranate (Punica granatum L.) is valued for its numerous bioactive substances, such as phenols, flavonoids, and tannins, which provide to its numerous health-enhancing properties. Obje…
Article
Evaluation of a Tagetes erecta Flower Extract Cream for Psoriasis-Relevant Anti-Inflammatory and Antioxidant Effects
Sanober Kamal, Fatima Qamar, Aymen Owais, Hoor Nasir, Asma Wazir, Syed Shafqat Ali Shah, Maria Rahat, Iqra Kanwal
pp. 971–986 · DOI: 10.5530/pres.20260294 · Published Jul-Sep 2026
Background Psoriasis is a chronic inflammatory skin disease in which the use of conventional therapies is often associated with adverse effects; therefore, medicinal plants with antioxidant and anti-inflammatory properti…
Article
Antioxidant Characterization of Aqueous Extract of Terminalia chebula Fruit Pulp Using Complementary Phytochemical and Spectroscopy Approaches
Biswajit Das, S Narayan, BS Sachin, Arbind Kumar Choudhary, Radhakrishnan Narayanaswamy
pp. 987–996 · DOI: 10.5530/pres.20260293 · Published Jul-Sep 2026
Background and Objectives Oxidative stress plays a central role in the pathogenesis of numerous chronic diseases, prompting growing interest in plant-derived natural antioxidants. The present study aimed to comprehensive…
Article
Evaluation of Antidepressant Activity of Emblica officinalis in Albino Wistar Rats
Shariq Ahmad Azmi, Syed Ziaur Rahman, Mehtab Parveen
pp. 997–1005 · DOI: 10.5530/pres.20260295 · Published Jul-Sep 2026
Background Major depressive disorder is a multifactorial neuropsychiatric condition characterized by incomplete therapeutic response and tolerability issues associated with currently available antidepressant drugs. This …

Case Report

Article
Acne and Premenstrual Syndrome in a Final-Year Medical Student: Case Report on Combined Drug and Herbal Management
Safaa Mohammed Alsanosi
pp. 1076–1079 · DOI: 10.5530/pres.20260309 · Published Jul-Sep 2026
Acne vulgaris and Premenstrual Syndrome (PMS) are common among women of reproductive age and often share hormonal, inflammatory, and psychosocial triggers. In high-stress settings such as medical training, the manifestat…

Review Article

Review
Herbal Remedies for Diabetes: Efficacy, Safety, and Standardization
B L Siddesh, Shivakumar, Yarava Dhanush, Purnima Chettri, Sadhu Nelson Kumar, P Gowtham Kumar Reddy, P A M Sucharitha, Vakkalagadda Siva Ganesh
pp. 632–643 · DOI: 10.5530/pres.20260101 · Published Jul-Sep 2026
Background/Objectives The global rise in diabetes mellitus has intensified the search for effective management strategies, including the use of herbal remedies. These natural interventions are increasingly recognised for…
Review
Innovative Approaches to Wound Healing with Phytoconstituents from Indian and Chinese Medicinal Plants
Rohit Verma, Prem Prakash Singh, Alok Kumar Mahor
pp. 644–655 · DOI: 10.5530/pres.20260119 · Published Jul-Sep 2026
Wound healing remains a major challenge in healthcare, with current treatments often limited by high cost, side effects, or lack of efficacy. Traditional medicine systems in India and China have long used medicinal plant…
Review
Recent Advances in Nanoparticle Preparation from Cassia auriculata: Pharmacognostical and Biological Perspectives
Gunavathi Honnashettihalli Dharmaraj, Pavithra Dharmappa, Abhishek Pete Nagaraj, Purushotham Karadigere Nagaraju
pp. 656–662 · DOI: 10.5530/pres.20260134 · Published Jul-Sep 2026
This review provides a comprehensive overview of Cassia auriculata Linn., focusing on its morphological traits and the synthesis of nanoparticles from its leaf and flower extracts. With a rich phytochemical composition, …
Review
Understanding Alopecia and the Potential of Herbal Interventions
Sunil Kardani, Ghanshyam Parmar, Jay Chudasama, Dipti Gohil, Rajesh Hadia, Chintan Tank, Rajesh Maheshwari, Avinash Seth
pp. 663–672 · DOI: 10.5530/pres.20260179 · Published Jul-Sep 2026
Androgenetic Alopecia (AGA), a common form of hair loss, significantly impacts individuals globally. While conventional treatments exist, interest in natural alternatives is growing due to potential side effects and vary…
Review
Neuroprotective Effects of Salvia rosmarinus in Cognitive Stress
Ana Lúcia Abdo Ladeira
pp. 673–678 · DOI: 10.5530/pres.20260216 · Published Jul-Sep 2026
Cognitive impairment under conditions of sustained physiological stress, such as chronic workload or extreme environments like spaceflight, presents a critical challenge to human performance and operational safety. This …
Review
An Updated Review on Phytochemistry of Plumeria alba L. (Apocynaceae)
Satyavarapu Veera Venkata Naga Satya Maha Lakshmi, Katam Teja Sri, Kokku Naveen Kumar, Kolepaka Supraja, Koppujola Manisha
pp. 679–697 · DOI: 10.5530/pres.20260257 · Published Jul-Sep 2026
Plumeria alba L. (Apocynaceae) is an ornamental tree widely distributed in tropical and subtropical regions and is well recognized in traditional medicine. Over the decades, extensive phytochemical investigations have be…
Review
Sapindus mukorossi Bio actives: Ethnomedicinal Importance, Pharmacological Potential and Molecular Docking Analysis
Neeraj Maurya, Ankit Kumar Verma, Raj Pal, Prashant Kumar, Pawan Kumar Gupta, Yogendra Pal, Shiv Dev Singh, Shashi Bhooshan Tiwari
pp. 698–709 · DOI: 10.5530/pres.20260312 · Published Jul-Sep 2026
Sapindus mukorossi (soapberry) is a deciduous tree widely distributed across Asia and extensively used in Ayurvedic, Chinese and folk medicine for managing diverse ailments. Its pericarp, seeds, leaves, roots and galls h…
Review
One Fruit, Many Effects: Understanding the Biological, Nutritional, and Therapeutic Roles of Malus domestica
Vakkalagadda Ravi Kumar, Reena Singh, Tandrima Majumder, Ameeduzzafar Zafar, Sayyad Mustak, Shaik Harun Rasheed, Sandip Sen
pp. 710–721 · DOI: 10.5530/pres.20260289 · Published Jul-Sep 2026
Apple (Malus domestica), belong to Rosaceae family; attract the world due to exceptional economic, nutritional, and medicinal significance. In India, apple cultivation is primarily concentrated in the Himalayan states Ja…
Review
Exploring the Mechanisms and Therapeutic Potential of Rhus chinensis Mill in Managing Type 2 Diabetes Mellitus: A Comprehensive Review
Thokchom Biona, Kalpana Rahate
pp. 722–732 · DOI: 10.5530/pres.20260254 · Published Jul-Sep 2026
The ethnomedicinal plant Rhus chinensis Mill., used extensively throughout Asia, has drawn scientific interest due to its potential use in treating Type 2 Diabetes Mellitus (T2DM). This comprehensive review investigates …