Volume 8, Issue 4

ORIGINAL ARTICLE

1. Article

   In vivo Study on Depressant Effects and Muscle Coordination Activity of Galphimia glauca Stem Methanol Extract

   Baba Shankar Rao Garige, Srisailam Keshetti, Uma Maheshwara Rao Vattikuti

   pp. 219–225 · DOI: 10.4103/0974-8490.188878 · Published Oct-Dec 2016

   Background Galphimia glauca is an evergreen shrub found across peninsular India, belonging to family Malpighiaceae. Objective The objective of this study was to assess the in vivo depressant effects and muscle coordinati…

2. Article

   Evaluation of Antiulcer and Antioxidant Activity of Barleria gibsoni Dalz. Leaves

   Firoj A. Tamboli, Harinath N. More

   pp. 226–230 · DOI: 10.4103/0974-8490.188879 · Published Oct-Dec 2016

   Background Peptic ulcer is a digestive disorder most commonly found in clinical practice. Given the many side effects of modern medicine, the initial acquisition of fewer side effects, and medication of indigenous drugs,…

3. Article

   Probing Regenerative Potential of Moringa oleifera Aqueous Extracts Using In vitro Cellular Assays

   Evangeline E. Fernandes, Anubha V. Pulwale, Gauri A. Patil, Alpana S. Moghe

   pp. 231–237 · DOI: 10.4103/0974-8490.188877 · Published Oct-Dec 2016

   Background Molecules stimulating regeneration and proliferation of cells are of significance in combating ailments caused due to tissue injury, inflammation, and degenerative disorders. Moringa oleifera is one of the mos…

4. Article

   High-performance Thin-layer Chromatography Method Development, Validation, and Simultaneous Quantification of Four Compounds Identified in Standardized Extracts of Orthosiphon stamineus

   Suzana Hashim, Hooi Kheng Beh, Mohamad Shahrul Ridzuan Hamil, Zhari Ismail, Amin Malik Shah Abdul Majid

   pp. 238–243 · DOI: 10.4103/0974-8490.188872 · Published Oct-Dec 2016

   Context Orthosiphon stamineus is a medicinal herb widely grown in Southeast Asia and tropical countries. It has been used traditionally as a diuretic, abdominal pain, kidney and bladder inflammation, gout, and hypertensi…

5. Article

   Kayeassamin A Isolated from the Flower of Mammea siamensis Triggers Apoptosis by Activating Caspase-3/-8 in HL-60 Human Leukemia Cells

   Takuhiro Uto, Nguyen Huu Tung, Pinjutha Thongjankaew, Sorasak Lhieochaiphant, Yukihiro Shoyama

   pp. 244–248 · DOI: 10.4103/0974-8490.188884 · Published Oct-Dec 2016

   Background Mammea siamensiŝ(Miq.) T. Anders. is used as a medicinal plant in Thailand and has several traditional therapeutic properties. In a previous study, we isolated eight compounds from the ˚ower of M. siamensis an…

6. Article

   Effect of Musa sapientum Stem Extract on Animal Models of Depression

   Aditya J. Reddy, Shailendra S. Handu, Ashok Kumar Dubey, Pramod Kumari Mediratta, Rimi Shukla, Qazi Mushtaq Ahmed

   pp. 249–252 · DOI: 10.4103/0974-8490.188876 · Published Oct-Dec 2016

   Background Musa sapientum, the banana plant, has shown to possess antioxidant activity in previous studies. Oxidative stress has been linked to the pathogenesis of major depressive disorder (MDD) with evidence of increas…

7. Article

   Chemical Characterization and Cytoprotective Effect of the Hydroethanol Extract from Annona coriacea Mart. (Araticum)

   José G. A. S. Júnior, Henrique D. M. Coutinho, Ticiana C. C. Boris, Janyketchuly S. Cristo, Nara L. F. Pereira, Fernando G. Figueiredo, Francisco A. B. Cunha, Pedro E. A. Aquino, Polyana A. C. Nascimento, Francisco J. C. Mesquita, Paulo H. F. Moreira, Sáskia T. B. Coutinho, Ivon T. Souza, Gabriela C. Teixeira, Najla M. N. Ferreira, Eleonora O. Farina, Cícero M. G. Torres, Vanderlan N. Holanda, Vandbergue S. Pereira, Maria I. F. Guedes

   pp. 253–257 · DOI: 10.4103/0974-8490.188882 · Published Oct-Dec 2016

   Introduction Annona coriacea Mart. (araticum) is a widely distributed tree in the cerrado. Its value is attributed principally to the consumption of its fruit which possesses a large nutritive potential. The objective wa…

8. Article

   In vitro Antioxidant Activities and Polyphenol Contents of Seven Commercially Available Fruits

   Paramita Basu, Camelia Maier

   pp. 258–264 · DOI: 10.4103/0974-8490.188875 · Published Oct-Dec 2016

   Background Fruits are considered one of the richest sources of natural antioxidants. Their consumption has been linked to the prevention of oxidative stress-induced diseases. Objective In this study, in vitro antioxidant…

9. Article

   Evaluation of In vitro Antiviral Activity of Datura metel Linn. Against Rabies Virus

   Soumen Roy, Sandeepan Mukherjee, Sandip Pawar, Abhay Chowdhary

   pp. 265–269 · DOI: 10.4103/0974-8490.188874 · Published Oct-Dec 2016

   Objective The soxhlet and cold extracts of Datura metel Linn. were evaluated for in vitro antirabies activity. Materials and Methods Soxhlet and cold extraction method were used to extract Datura (fruit and seed) extract…

10. Article

    Influence of the Extractive Method on the Recovery of Phenolic Compounds in Different Parts of Hymenaea martiana Hayne

    Fernanda Granja da Silva Oliveira, Sarah Raquel Gomes de Lima-Saraiva, Ana Paula Oliveira, Suzana Vieira Rabêlo, Larissa Araújo Rolim, Jackson Roberto Guedes da Silva Almeida

    pp. 270–275 · DOI: 10.4103/0974-8490.188885 · Published Oct-Dec 2016

    Background Popularly known as “jatobá,” Hymenaea martiana Hayne is a medicinal plant widely used in the Brazilian Northeast for the treatment of various diseases. Objective The aim of this study was to evaluate the influ…

11. Article

    Anti-Advanced Glycation End-product and Free Radical Scavenging Activity of Plants from the Yucatecan Flora

    Wendy del C. Dzib-Guerra, Fabiola Escalante-Erosa, Karlina García-Sosa, Séverine Derbré, Patricia Blanchard, Pascal Richomme, Luis M. Peña-Rodríguez

    pp. 276–280 · DOI: 10.4103/0974-8490.188883 · Published Oct-Dec 2016

    Background Formation and accumulation of advanced glycation end- products (AGE) is recognized as a major pathogenic process in diabetic complications, atherosclerosis and cardiovascular diseases. In addition, reactive ox…

12. Article

    Elucidation of Flavonoids from Carissa congesta, Polyalthia longifolia, and Benincasa hispida Plant Extracts by Hyphenated Technique of Liquid Chromatography-mass Spectroscopy

    Gaurav M. Doshi, Vivek V. Nalawade, Aaditi S. Mukadam, Pratip K. Chaskar, Sandeep P. Zine, Rakesh R. Somani, Hemant D. Une

    pp. 281–286 · DOI: 10.4103/0974-8490.186578 · Published Oct-Dec 2016

    Background Carissa congesta (CC), Polyalthia longifolia (PL), and Benincasa hispida (BH) are economically important plants. Objective Current research encompasses identification of quercetin and rutin and their analogues…

13. Article

    Bioactivity of Diterpens from the Ethyl Acetate Extract of Kingiodendron pinnatum Rox. Hams

    Komal Kumar Javarappa, Attemode Girijanna Devi Prasad, AJ Mahadesh Prasad, Chetana Mane

    pp. 287–291 · DOI: 10.4103/0974-8490.188871 · Published Oct-Dec 2016

    Background Kingiodendron pinnatum Rox. Hams. is an endangered medicinal plant used in gonorrhoe, catarrhal conditions of genito-urinary and respiratory tracts. The scientific and pharmacological formulation of K. pinnatu…

14. Article

    Inhibition of Human Cytochrome P450 2C8-catalyzed Amodiaquine N-desethylation: Effect of Five Traditionally and Commonly Used Herbs

    Yasotha Devi Muthiah, Chin Eng Ong, Siti Amrah Sulaiman, Rusli Ismail

    pp. 292–297 · DOI: 10.4103/0974-8490.188886 · Published Oct-Dec 2016

    Background In Southeast Asia and many parts of the world, herbal products are increasingly used in parallel with modern medicine. Objective This study aimed to investigate the effects of herbs commonly used in Southeast …

15. Article

    Wound Healing Activity of Silibinin in Mice

    Rojalini Samanta, Ashok K. Pattnaik, Kishanta K. Pradhan, Beena K. Mehta, Shakti P. Pattanayak, Sugato Banerjee

    pp. 298–302 · DOI: 10.4103/0974-8490.188880 · Published Oct-Dec 2016

    Background Silibinin is a semi-purified fraction of silymarin contained in milk thistle (Silybum marianum Asteraceae). Primarily known for its hepatoprotective actions, silymarin may also stimulate epithelialization and …

16. Article

    Antihyperglycemic and Insulin Secretagogue Activities of Abrus precatorius Leaf Extract

    Balekari Umamahesh, Ciddi Veeresham

    pp. 303–308 · DOI: 10.4103/0974-8490.188881 · Published Oct-Dec 2016

    Aim Abrus precatorius leaves methanolic extract (APME) was evaluated for in vivo antihyperglycemic activity and in vitro insulinotropic effect. Materials and Methods In vivo antihyperglycemic and insulin secretagogue act…

17. Article

    Effects of Curcuma xanthorrhiza Extracts and Their Constituents on Phase II Drug-metabolizing Enzymes Activity

    Nurul Afifah Mohd Salleh, Sabariah Ismail, Mohd Rohaimi Ab Halim

    pp. 309–315 · DOI: 10.4103/0974-8490.188873 · Published Oct-Dec 2016

    Background Curcuma xanthorrhiza is a native Indonesian plant and traditionally utilized for a range of illness including liver damage, hypertension, diabetes, and cancer. Objective The study determined the effects of C. …