Volume 17, Issue 5S

Original Article

1. Article

   The Traditional Medicine Bojungikki‑Tang Increases Intestinal Motility

   Hyo Eun Kwon, Jeong Nam Kim, Min Ji Kwon, Jong Rok Lee, Sang Chan Kim, Joo Hyun Nam, Byung Joo Kim

   pp. S1–S8 · DOI: 10.4103/pm.pm_507_20 · Published 10 June 2021

   Objectives: We investigated the GI motility functions in vivo and the pacemaker potential in interstitial cells of Cajal (ICCs) in vitro by BJIT. Materials and Methods: Intestinal transit rate (ITR) and serum levels of G…

2. Article

   Ethyl Acetate Fraction of Anethum graveolens Seeds Exerts an Antiproliferative Effect by Inhibiting Anti‑apoptotic Proteins in MCF‑7 and PC‑3 Cells: An in vitro and Molecular Docking Study

   Furkhan Ahmed Mohammed, Waseem Mohammed Abdul, Md Tabish Rehman, Mohamed F. AlAjmi, Fareeduddin Quadri Syed, Muqtadir Baig Mirza, Ayman I. Elkady, Anzarul Haque, Muhummadh Khan

   pp. S105–S113 · DOI: 10.4103/pm.pm_538_20 · Published 10 June 2021

   Objectives: We investigated, the antiproliferative effect of ethyl acetate fraction of dill (EAFD), on MCF‑7 and PC‑3 cell lines and its two most active components, anethole and carvone by molecular docking analysis. Mat…

3. Article

   Genotoxic Assay of Silver and Zinc Oxide Nanoparticles Synthesized by Leaf Extract of Garcinia livingstonei T. Anderson: A Comparative Study

   Azharuddin B. Daphedar, Siddappa B. Kakkalameli, Govindappa Melappa, Tarikere Chandrashekharappa Taranath, Chandrashekar Srinivasa, Chandan Shivamallu, Asad Syed, Najat Marraiki, Abdallah M. Elgorban, Ravindra Veerapur, Sharangouda S Patil, Shiva Prasad Kollur

   pp. S114–S121 · DOI: 10.4103/pm.pm_536_20 · Published 10 June 2021

   Objectives: The as‑prepared NPs were characterized by ultraviolet‑visible spectroscopy, infrared spectroscopy (FT‑IR), X‑ray diffraction (XRD), atomic force microscopy (AFM), and high‑resolution transmission electron mic…

4. Article

   Antihyperglycemic Activity of Achyranthes aspera Linn. Leaves Extract by Modulation of β‑cell Functioning in Streptozotocin‑Induced Diabetic Rats

   Hemant D. Une, Trupti C. Deshpande

   pp. S15–S20 · DOI: 10.4103/pm.pm_296_20 · Published 10 June 2021

   Objective: The objective of the study is to study the anti‑hyperglycemic potential of Ethyl Acetate dissolved fraction of methanolic extract of Achyranthes aspera Linn. (EAAA) leaves on STZ induced diabetic rat model. Ma…

5. Article

   Phytochemical Screening and Antioxidant Activity of the Methanolic Extract of the Leaves of Cinnamomum tamala

   Asna Khan, Sultan Zahiruddin, Mohammad Ibrahim, Parakh Basist, Gaurav Gaurav, Rabea Parveen, Shahid Umar, Sayeed Ahmad

   pp. S21–S28 · DOI: 10.4103/pm.pm_326_20 · Published 10 June 2021

   Objectives: Carica papaya Linn. a member of the Caricaceae family, is a tropical fruit, rich in various secondary metabolites owing to its antioxidant, anti‑inflammatory, anti‑diabetic, and antihelmintic properties. The …

6. Article

   Isolation and Characterization of Flavonoids from Fraction of Blepharis persica (Burm. f.) O. Kuntze Upregulated Testosterone Biosynthesis in vitro using TM3 Leydig Cells

   Nilesh V. Gaikar, Manan A. Raval, Samir G. Patel, Lal L. Hingorani

   pp. S29–S37 · DOI: 10.4103/pm.pm_406_20 · Published 10 June 2021

   Objectives: The present study aimed to evaluate the effect of extract and fraction prepared from seeds of B. persica, in vitro using TM3 Leydig cells and isolation of constituents from bioactive fraction. Materials and M…

7. Article

   Callus Induction and Shoot Regeneration from the Immature Flower Bud of Caesalpinia bonducella and its Antileptospiral Potential by in vitro and in silico Analysis

   S. R. Santosh Kumar, Chandrashekar Srinivasa, Chandan Shivamallu, Kollur Shiva Prasad, Sushma Pradeep, Asad Syed, Ali Bhakali, Amar Shankar, Sharanagouda S Patil, Ashwini P, Chandan D, Triveni R, Govindappa Melappa, V. Krishna

   pp. S38–S44 · DOI: 10.4103/pm.pm_331_20 · Published 10 June 2021

   Objectives: The aim of the study is to establish the C. bonducella through tissue culture technique and to investigate the antileptospiral activity through computational and in vitro screening. Materials and Methods: Mor…

8. Article

   Quality Analysis of Manjishta (Rubia cordifolia L.) with Respect to Pharmacognostical and High‑Performance Thin‑Layer Chromatography Profile of the Genuine Sample: A Cross‑Sectional Market Sample Study

   Vivek Palengara, C. M. Harinarayanan, Pratibha P. Nair

   pp. S45–S53 · DOI: 10.4103/pm.pm_394_20 · Published 10 June 2021

   Objectives: To compare the six market samples of Manjishta (Pharmacognostical and with HPTLC profiling) with the genuine root and stolon. Materials and Methods: The market samples of Manjishta from 6 districts of Kerala …

9. Article

   Gas Chromatography‑Mass Spectrometry Fingerprint and in vitro Cytotoxic Studies of Rubus steudneri Leaf Fractions against Michigan Cancer Foundation‑7 Breast Cancer Cell Line

   Raghavendra Lakshmana Shetty Hallur, Chaitanya V. N. L. Motamarri, Prashith Kekuda T. Ramamoorthy, Chetan D. Murthy, Ravikumar Patil H. Siddappa, Vijayananda N. Bramhanakonda

   pp. S54–S62 · DOI: 10.4103/pm.pm_324_20 · Published 10 June 2021

   Aim: Rubus steudneri Schweinf. (Rosaceae) is one of three Rubus species that grow in Ethiopia. Studies of this species have been restricted to in vitro antioxidant, antidiabetic, and nutritional evaluation. Until today, …

10. Article

    Antioxidant and Anticancer Activities of Whole Plant Extracts of Lepidagathis pungens Nees: In vitro Evaluation

    Manoharan Dhanalakshmi, Subramaniam Ananda Thangadurai

    pp. S63–S67 · DOI: 10.4103/pm.pm_356_20 · Published 10 June 2021

    Objective: The present study was planned to evaluate antioxidant activities, anticancer activity of Lepidagathis pungens Nees., whole plant (L. pungens). Materials and Methods: Antioxidants activity of the ethanol extrac…

11. Article

    GC‑MS/MS‑Based Phytochemical Screening of Therapeutic Potential of Calligonum polygonoides L. Flower Bud against Chronic Diseases

    Mukesh Kumar Berwal, Shravan M. Haldhar, Chet Ram, Jagan Singh Gora, Dhurendra Singh, D. K. Samadia

    pp. S68–S76 · DOI: 10.4103/pm.pm_390_20 · Published 10 June 2021

    Background: Calligonum polygonoides is an endemic plant species, belongs to Polygonaceae family, native to the “Thar Desert” of India. It is highly tolerant to multiple stresses with dominant biomass and phytochemical pr…

12. Article

    Evaluation of CYP2D, CYP1A2 and Distribution of Tetrandrine, Fangchinoline in the Brain, Liver, and Kidney of Wistar Rats after Short‑Term Exposure to Cyclea peltata

    G. I. Anuja, V. J. Shine, P. G. Latha, S. R. Suja, Swapna Susan Abraham, Vinodkumar T. G. Nair, S. Rajasekharan

    pp. S77–S86 · DOI: 10.4103/pm.pm_166_20 · Published 10 June 2021

    Objectives: The aim of this study is to evaluate short‑term toxic effects of CP, tissue distribution of bioactive alkaloids tetrandrine, fangchinoline in the brain, liver, kidney, and mRNA expression of CYP2D, CYP1A2 aft…

13. Article

    Camptothecin: An Anticancer Drug from Pestalotiopsis

    microspora Mh458929 – An Endophytic Fungus Isolated from

    pp. S87–S95 · DOI: 10.4103/pm.pm_417_20 · Published 10 June 2021

    Objectives: Isolation, screening, and in silico toxicity evaluation of camptothecin (CPT) from the endophytic fungus Pestalotiopsis microspora MH458929. Materials and Methods: Endophytic fungus was isolated from leaves o…

14. Article

    Immunomodulatory and Cytotoxic Properties of Natural Triterpenoids Isolated from Grewia flavescens Juss

    Gihan O. M. ELhassan, Sakina Yagi, M. Ahmed Mesaik, Syam Mohan, Hassan A. Alhazmi, Mohammed Al‑Bratty, Marai M. Al‑Amri, Asaad Khalid

    pp. S9–14 · DOI: 10.4103/pm.pm_235_20 · Published 10 June 2021

    Objectives: The present investigation was undertaken to examine the immunomodulatory and cytotoxic properties of natural triterpenoids isolated from the stem bark of G. flavescens. Materials and Methods: The immunomodula…

15. Article

    Apoptosis‑Inducing and Antiangiogenic Activity of Partially Purified Protein from the Pericarp of Zanthoxylum rhetsa in vitro and in vivo

    Priyanka Dattaraj Naik Parrikar, Balaji Kyathegowdanadoddi Srinivas, Dharmappa Kattepura Krishnappa, Shankar Jayarama

    pp. S96–104 · DOI: 10.4103/pm.pm_520_20 · Published 10 June 2021

    Objectives: The study assessed the proapoptotic and antiangiogenic activity of partially purified proteins from the pericarp of Z. rhetsa. Methods: MCF‑7, MDA MB 231, HeLa, and HCT 116 cells treated with partially purifi…