Volume 13, Issue 51

2026-09-10 · pp. · 31 articles

Volume: 13
Issue: 51
Published: 2026-09-10
Pages
Articles: 31
Sections: 2
ISSN: ISSN: Print - 0973-1296, Online - 0976-4062
Journal: Pharmacogn. Mag.

ORIGINAL ARTICLE Original Article

In this issue

ORIGINAL ARTICLE

Article
Quantification Analysis and In Vitro Anti-Inflammatory Effects of 20-Hydroxyecdysone, Momordin Ic, and Oleanolic Acid from the Fructus of Kochia scoparia
Sae-Rom Yoo, Soo-Jin Jeong, Na-Ri Lee, Hyeun-Kyoo Shin, Chang-Seob Seo
pp. 339–344 · DOI: 10.4103/0973-1296.211023 · Published 19 July 2017
Background: The fructus of Kochia scoparia Schrader (Chenopodiaceae) is a traditional herbal medicine that has been used for treating gonorrhea and dermatitis. Objective: We investigated the anti-inflammatory activities …
Article
Ethanolic Fraction of Terminalia tomentosa Attenuates Biochemical and Physiological Derangements in Diet Induced Obese Rat Model by Regulating Key Lipid Metabolizing Enzymes and Adipokines
Balaji Meriga, Parim Brahma Naidu, Ganjayi Muniswamy, GEN Hanuma Kumar, Ramavat Ravindar Naik, Suresh Pothani
pp. 385–92 · DOI: 10.4103/0973-1296.208871 · Published 22 June 2017
The prevalence of overweight-obesity and associated comorbidities have reached alarming levels necessitating the need to explore effective therapeutics. In the present work, we demonstrated the promising antiobesity acti…
Article
Effects of Plantago major Extracts and Its Chemical Compounds on Proliferation of Cancer Cells and Cytokines Production of Lipopolysaccharide-activated THP-1 Macrophages
Kartini, Suratsawadee Piyaviriyakul, Suchitra Thongpraditchote, Pongpun Siripong, Omboon Vallisuta
pp. 393–399 · DOI: 10.4103/pm.pm_406_16 · Published 19 July 2017
Background: Plantago major has been reported to have anticancer and anti‑inflammatory properties. However, its antiproliferative and anti‑inflammatory mechanisms have not been fully elucidated. Moreover, which plant part…
Article
Intervention Effects of Atorvastatin Combined with Panax notoginseng Saponins on Rats with Atherosclerosis Complicated with Hepatic Injury
Qing-Fang Jiang, Min-Yi Huang, Kang-Yuan Wu, Jie-Ling Weng, Rong-Gui Deng, Xin-Jie Xu, Jian-Pei Xu, Tao Jiang
pp. 430–8 · DOI: 10.4103/pm.pm_424_16 · Published 19 July 2017
Background: Statins cannot be used for some active liver diseases, which limits its application to some extent. The combined use of statins with other drugs may be one of the ways to solve this dilemma. Objective: This r…
Article
Rapid Detection of Volatile Oil in Mentha haplocalyx by Near-Infrared Spectroscopy and Chemometrics
Hui Yan, Cheng Guo, Yang Shao, Zhen Ouyang
pp. 439–445 · DOI: 10.4103/0973-1296.211026 · Published 19 July 2017
Near-infrared spectroscopy combined with partial least squares regression (PLSR) and support vector machine (SVM) was applied for the rapid determination of chemical component of volatile oil content in Mentha haplocalyx…
Article
Berberine Depresses Contraction of Smooth Muscle via Inhibiting Myosin Light‑chain Kinase
Zhili Xu, Mingbo Zhang, Deqiang Dou, Xiaojun Tao, Tingguo Kang
pp. 454–458 · DOI: 10.4103/pm.pm_205_16 · Published 19 July 2017
Background: Berberine is a natural isoquinoline alkaloid possessing various pharmacological effects, particularly apparent in the treatment of diarrhea, but the underlying mechanism remains unclear. Smooth muscle myosin …
Article
Preparation and Bioactivity of Exopolysaccharide from an Endophytic Fungus Chaetomium sp. of the Medicinal Plant Gynostemma Pentaphylla
Huiru Zhang, Xueqin Wang, Ruifang Li, Xincheng Sun, Siwen Sun, Qiang Li, Chunping Xu
pp. 477–82 · DOI: 10.4103/0973-1296.211033 · Published 19 July 2017
Background: Many exopolysaccharides from the endophytes in medicinal plants possess various potential bioactivities. Materials and Methods: The endophytic fungus JY25 was isolated from the leave of the Chinese medicinal …
Article
Decoction of Dictamnus Dasycarpus Turcz. Root Bark Ameliorates Skin Lesions and Inhibits Inflammatory Reactions in Mice with Contact Dermatitis
Beodeul Yang, Hong-Bum Lee, Sura Kim, Young Chul Park, Koanhoi Kim, Hyungwoo Kim
pp. 483–7 · DOI: 10.4103/0973-1296.211034 · Published 19 July 2017
Background: The root bark of Dictamnus dasycarpus Turcz. (Dictamni Radicis Cortex) has been widely used to treat skin diseases in Korea, and its anti-inflammatory efficacies were recently reported. Objective: The paper a…
Article
Withaferin-A Induces Apoptosis in Osteosarcoma U2OS Cell Line via Generation of ROS and Disruption of Mitochondrial Membrane Potential
Hui-Liang Zhang, Hong Zhang
pp. 523–7 · DOI: 10.4103/0973-1296.211042 · Published 19 July 2017
Background: Withaferin-A (WF-A) is a well-known dietary compound isolated from Withania sominifera. It has tremendous pharmacological potential and has been shown to exhibit antiproliferative activity against several typ…

Original Article

Article
Anticancer Potential of Steviol in MCF-7 Human Breast Cancer Cells
Ena Gupta, Shweta Kaushik, Shalini Purwar, Ramesh Sharma, Anil K. Balapure, Shanthy Sundaram
pp. 345–350 · DOI: 10.4103/pm.pm_29_17 · Published 19 July 2017
Objective: This study aimed to investigate the cytotoxicity, apoptosis induction, and mechanism of action of steviol on human breast cancer cells (Michigan Cancer Foundation‑7 [MCF‑7]). Materials and Methods: Sulforhodam…
Article
Antitumor Effects and Mechanism of n‑butanol Fraction from Aril of Torreya grandis in H22 Mice
Fang-fang Duan, Shan-shan Jia, Ke Yuan
pp. 351–357 · DOI: 10.4103/pm.pm_286_16 · Published 19 July 2017
Background: To determine the antitumor effects and its mechanism of n‑butanol fraction from aril of Torreya grandis (BFAT) on H22 mice models of liver cancer. Materials and Methods: Sixty ICR male mice were used to estab…
Article
Using Molecular Docking Analysis to Discovery Dregea sinensis Hemsl. Potential Mechanism of Anticancer, Antidepression, and Immunoregulation
Xiujie Liu, Yu Shi, Yulin Deng, Rongji Dai
pp. 358–362 · DOI: 10.4103/pm.pm_384_16 · Published 19 July 2017
Background: Dregea sinensis Hemsl. plant of the genus Dregea volubilis (Asclepiadaceae), plays a vital role in anticancer, antidepression, and immunoregulation. Steroidal glycosides are the main constituents of this herb…
Article
Wound‑healing Activity of Zanthoxylum bungeanum Maxim Seed Oil on Experimentally Burned Rats
Xiao‑Qiang Li, Rong Kang, Jun‑Cheng Huo, Yan‑Hua Xie, Si‑Wang Wang, Wei Cao
pp. 363–371 · DOI: 10.4103/pm.pm_211_16 · Published 19 July 2017
Background: The seed oil of Zanthoxylum bungeanum Maxim (ZBSO) is considered to be rich source of fatty acids, mainly oleic and linoleic acids, and has been used for the treatment of burns in Chinese medicine. Objective:…
Article
Mechanism of Fructus Aurantii Flavonoids Promoting Gastrointestinal Motility: From Organic and Inorganic Endogenous Substances Combination Point of View
Shuai Wang, Yong‑Rui Bao, Tian‑Jiao Li, Ting Yu, Xin Chang, Guan‑Lin Yang, Xian‑Sheng Meng
pp. 372–377 · DOI: 10.4103/pm.pm_179_16 · Published 19 July 2017
Background: Fructus Aurantii (FA) derived from the dried, and unripe fruit of Citrus aurantium L. is one of the commonly used traditional Chinese medicines to treat gastrointestinal motility dysfunction diseases. Accordi…
Article
Prim‑O‑glucosylcimifugin Attenuates Lipopolysaccharide‑ induced Inflammatory Response in RAW 264.7 Macrophages
Jie Zhou, Yuan‑Yuan Sun, Meng‑Yao Sun, Wei‑An Mao, Li Wang, Jian Zhang, Hong Zhang
pp. 378–384 · DOI: 10.4103/pm.pm_323_16 · Published 19 July 2017
Background: Radix Saposhnikoviae (RS) exerts anti‑inflammatory, analgesic, antipyretic, antioxidation effects and has been used in traditional Chinese medicine to treat common colds, headache, and rheumatoid arthritis. P…
Article
A Novel Strategy for Bitter Taste Masking of Gankeshuangqing Dispersible Tablets Based on Particle Coating Technology
Xue Han, Ding-Kun Zhang, Fang Zhang, Jun-Zhi Lin, Hong Jiang, Yang Lan, Xi Xiong, Li Han, Ming Yang, Chao-Mei Fu
pp. 400–406 · DOI: 10.4103/pm.pm_240_16 · Published 19 July 2017
Background: Currently, acute upper respiratory tract infections (AURTIs) are increasingly becoming a significant health burden. Gankeshuangqing dispersible tablets (GKSQDT) which have a good effect on treating AURTIs. GK…
Article
Omega‑3 Fish Oil Reduces Mortality Due to Severe Sepsis with Acute Gastrointestinal Injury Grade III
Huaisheng Chen, Wei Wang, Chengying Hong, Ming Zhang, Yingcai Hong, Su Wang, Huadong Zhang
pp. 407–412 · DOI: 10.4103/pm.pm_418_16 · Published 19 July 2017
Background: Sepsis plays an important role in acute gastrointestinal injury (AGI). Our research was designed to determine the effects of omega-3 fish oil (FO) in patients suffering from severe sepsis combined with AGI II…
Article
Determination and Tissue Distribution Comparisons of Atractylodin after Oral Administration of Crude and Processed Atractylodes Rhizome
Yang-Zhi Liu, Yu-Qiang Liu, Rui Jia, Jun Li, Xiao-Wen Chang, Chen-Xi Xu, Qian Cai
pp. 413–417 · DOI: 10.4103/pm.pm_394_16 · Published 19 July 2017
Background: Atractylodis rhizoma is one of the most often used drugs in traditional Chinese medicine. Stir frying with wheat bran is the most common processing method. To clarify the principle of processing, an experimen…
Article
Influence of Boiling Duration of GCSB-5 on Index Compound Content and Antioxidative and Anti-inflammatory Activity
In-Hee Lee, Hwa-Jin Chung, Joon-Shik Shin, In-Hyuk Ha, Me-Riong Kim, Wonil Koh, Jinho Lee
pp. 418–424 · DOI: 10.4103/pm.pm_425_16 · Published 19 July 2017
Background: GCSB-5, an herbal drug composition with an anti-inflammatory effect, is prepared by boiling, which is the most common herbal extraction method in traditional Korean medicine. Several parameters are involved i…
Article
Simultaneous Quantitation of Six Aconitum Alkaloids and Three Flavonoids in the Herb Couple of Radix Aconiti Lateralis-Radix Glycyrrhizae (Fuzi–Gancao) by UHPLC-ESI-MS/MS
Xiao Fu, Rongrong Lu, Songsong Zhao
pp. 425–429 · DOI: 10.4103/pm.pm_141_16 · Published 19 July 2017
Background: Fuzi–Gancao herb couple is one of the commonly used herb couples involved in the traditional Chinese medicine formulations, with radix aconiti lateralis (Fuzi in Chinese) and radix glycyrrhizae (Gancao in Chi…
Article
Optimization of Surfactant‑Mediated, Ultrasonic‑assisted Extraction of Antioxidant Polyphenols from Rattan Tea (Ampelopsis grossedentata) Using Response Surface Methodology
Feng Li, Aun Raza, Yan‑Wei Wang, Xiu‑Quan Xu, Guan‑Hua Chen
pp. 446–453 · DOI: 10.4103/pm.pm_159_16 · Published 19 July 2017
Background: Rattan tea is a medicinal plant that has been used for many years for the treatment of inflammation, fatty liver, tumor, diabetes, and hyperlipidemia. Objective: A green and novel approach based on surfactant…
Article
Quassinoids from the Root of Eurycoma longifolia and Their Antiproliferative Activity on Human Cancer Cell Lines
Nguyen Huu Tung, Takuhiro Uto, Nguyen Thanh Hai, Gang Li, Yukihiro Shoyama
pp. 459–462 · DOI: 10.4103/pm.pm_353_16 · Published 19 July 2017
Background: The roots of Eurycoma longifolia Jack have traditionally been used as an aphrodisiac tonic besides the other remedies for boils, fever, bleeding gums, and wound ulcer. Recently, the antiproliferative activity…
Article
Comparative Analysis of Transcriptomes of Macrophage Revealing the Mechanism of the Immunoregulatory Activities of a Novel Polysaccharide Isolated from Boletus speciosus Frost
Xiang Ding, Hongqing Zhu, Yiling Hou, Wanru Hou, Nan Zhang, Lei Fu
pp. 463–471 · DOI: 10.4103/pm.pm_151_16 · Published 19 July 2017
Background: The mechanism of the immunoregulatory activities of polysaccharide is still not clear. Materials and Methods: Here, we performed the B‑cell, T‑cell, and macrophage cell proliferation, the cell cycle analysis …
Article
Hepatoprotective Flavonoids in Opuntia ficus‑indica Fruits by Reducing Oxidative Stress in Primary Rat Hepatocytes
Jung Wha Kim, Tae Bum Kim, Hyun Woo Kim, Sang Wook Park, Hong Pyo Kim, Sang Hyun Sung
pp. 472–476 · DOI: 10.4103/pm.pm_232_16 · Published 19 July 2017
Background: Liver disorder was associated with alcohol consumption caused by hepatic cellular damages. Opuntia ficus‑indica fruit extracts (OFIEs), which contain betalain pigments and polyphenols including flavonoids, ha…
Article
Flavones and Lignans from the Stems of Wikstroemia scytophylla Diels
Jie-Ping Lei, Juan-Juan Yuan, Sheng-Hao Pi, Rui Wang, Rui Tan, Chao-Ying Ma, Tao Zhang, He-Zhong Jiang
pp. 488–491 · DOI: 10.4103/pm.pm_275_16 · Published 19 July 2017
Background: The genus Wikstroemia has about 70 species, but only a limited number of species have been studied chemically. Wikstroemia indica has long been used as a traditional crude drug in China. However, there is no …
Article
A Novel Quantitative Prediction Approach for Astringency Level of Herbs Based on an Electronic Tongue
Xue Han, Hong Jiang, Dingkun Zhang, Yingying Zhang, Xi Xiong, Jiaojiao Jiao, Runchun Xu, Ming Yang, Li Han, Junzhi Lin
pp. 492–497 · DOI: 10.4103/pm.pm_455_16 · Published 19 July 2017
Background: The current astringency evaluation for herbs has become dissatisfied with the requirement of pharmaceutical process. It needed a new method to accurately assess astringency. Methods: First, quinine, sucrose, …
Article
Characterization of Nano Bamboo Charcoal Drug Delivery System for Eucommia ulmoides Extract and Its Anticancer Effect In vitro
Zhaoyan Zeng, Xiangzhou Li, Sheng Zhang, Dan Huang
pp. 498–503 · DOI: 10.4103/pm.pm_256_16 · Published 19 July 2017
Background: Nano bamboo charcoal is being widely used as sustained release carrier for chemicals for its high specific surface area, sound biocompatibility, and nontoxicity; however, there have been no reports on nano ba…
Article
Optimization of Polysaccharide Ultrasonic Extraction Conditions Using Purple Sweet Potato Tubers Based on Free Radical Scavenging and Glycosylation Inhibitory Bioactivities
Haihua Guo, Fansheng Kong, Chunyan Yan
pp. 504–511 · DOI: 10.4103/0973-1296.211044 · Published 19 July 2017
Background: The purple sweet potato, Ipomoea batatas, belongs to the family Convolvulaceae. It is one of the most widely consumed tubers in Asia and is found in many dishes. Many people with diabetes eat purple sweet pot…
Article
Anti‑epileptic Effects of Valepotriate Isolated from Valeriana jatamansi Jones and Its Possible Mechanisms
An Wu, Xia Ye, Qiang Huang, Wei‑Min Dai, Jian‑Min Zhang
pp. 512–516 · DOI: 10.4103/0973-1296.211027 · Published 19 July 2017
Objective: This work aimed to investigate the anti‑epileptic effects of valepotriate isolated from Valeriana jatamansi Jones and studied its possible mechanisms. Methods: The anti‑epileptic effects of valepotriate were s…
Article
Sugemule-3 Protects against Isoprenaline-induced Cardiotoxicity In vitro
Yu Wang, Guo-Hua Gong, Ya-Nan Xu, Li-Jun Yu, Cheng-Xi Wei
pp. 517–522 · DOI: 10.4103/0973-1296.211018 · Published 19 July 2017
Background: Sugemule-3 (SD) is a traditional Chinese medicine with protective effect of myocardium. However, the underlying mechanisms of the effect had not been elucidated. Materials and Methods: In the present study, t…
Article
Quality Evaluation of Raw Moutan Cortex Using the AHP and Gray Correlation-TOPSIS Method
Sujuan Zhou, Bo Liu, Jiang Meng
pp. 528–533 · DOI: 10.4103/0973-1296.211029 · Published 19 July 2017
Background: Raw Moutan cortex (RMC) is an important Chinese herbal medicine. Comprehensive and objective quality evaluation of Chinese herbal medicine has been one of the most important issues in the modern herbs develop…