Volume 15, Issue 63

Original Article

1. Article

   The Role of the Herbal Medicines, Rehmanniae Radix, Citrus unshiu Peel, and Poria cocos Wolf, in High‑Fat Diet‑Induced Obesity

   Min Ji Kwon, Jung Nam Kim, Eun Yeong Lim, Yun Tai Kim, Hyungwoo Kim, Myeong Ho Jung, Byung Joo Kim

   pp. 363–368 · DOI: 10.4103/pm.pm_376_18 · Published 16 May 2019

   Objective: To investigate on the anti‑obesity effects of herbal medicines such as Rehmanniae radix (RR), Citrus unshiu peel (CUP), and Poria cocos wolf (PCW) in high‑fat diet (HFD)‑induced obese mice. Materials and Metho…

2. Article

   Effects of the Herbal Medicines on Voltage‑Dependent K+ 2 Channels

   Jeong Nam Kim, Eun Yeong Lim, Yun Tai Kim, Hyungwoo Kim, Byung Joo Kim

   pp. 369–377 · DOI: 10.4103/pm.pm_636_18 · Published 16 May 2019

   Objective: The aim of this study was to evaluate whether herbal medicines, such as the fruit of Schisandra chinensis (SCF), Atractylodes macrocephala Koidzumi (AMK), Poria cocos Wolf (PCW), Citrus unshiu peel (CUP), Magn…

3. Article

   Research on Mechanism of Traditional Hot Processing on Velvet Antler Based on 1H Nuclear Magnetic Resonance and Multivariate Statistical Analysis

   Jingfeng Li, Hui Sun, Xuefeng Bian, Nanxi Zhang, Yaping Wang, Ying Zong, Hui Zhang, Jiaming Sun

   pp. 378–384 · DOI: 10.4103/pm.pm_594_18 · Published 16 May 2019

   Objective: The aim of this study is to develop a method for exploring the mechanism of hot processing on velvet antler. Materials and Methods: In this study, the chemical compositions of fresh velvet antler (FVA) and hot…

4. Article

   The Effects of Polysaccharides from Rehmannia glutinosa on Caenorhabditis elegans

   Yanyan Yuan, Nianxin Kang, Yinghui Lu, Xiangzhen Miao, Xiao Zhang, Yonggang Liu, Peng Tan

   pp. 385–391 · DOI: 10.4103/pm.pm_618_18 · Published 16 May 2019

   Objective: To evaluate the stress resistances and anti-aging effects of polysaccharides from RG by Caenorhabditis elegans N2 wild type. Materials and Methods: Preparing the polysaccharides from Rehmanniae radix preparata…

5. Article

   Aroma Characteristic Analysis of Amomi fructus from Different Habitats using Machine Olfactory and Gas Chromatography‑Mass Spectrometry

   Huaying Zhou, Dehan Luo, Hamid Gholamhosseini, Zhong Li, Bin Han, Jiafeng He, Shumei Wang

   pp. 392–401 · DOI: 10.4103/pm.pm_665_18 · Published 16 May 2019

   Background: Amomi fructus (AF Lour.) has been used to treat digestive diseases in the context of Traditional Chinese Medicine. Its aroma characteristics have been attracted attention and are considered to be effective ma…

6. Article

   Protective Effect of Curcumin Decreases Incidence of Gastric Cancer Induced by Helicobacter pylori and N‑methyl‑N‑nitrosourea in Rats

   Duangporn Werawatganon, Kanjana Somanawat, Kawiya Sintara, Somying Tumwasorn, Naruemon Klaikeaw

   pp. 402–409 · DOI: 10.4103/pm.pm_621_18 · Published 16 May 2019

   Aim: To study the effects of curcumin on Helicobacter pylori and N‑methyl‑N‑nitrosourea (MNU)‑induced gastric cancer in rats. Materials and Methods: Male Wistar rats were divided into three groups: control (CO), H. pylor…

7. Article

   Rapid Identification of Medicinal Leech by Species‑Specific Polymerase Chain Reaction Technology

   Yang Zheng, Beibei Lu, Yaya Yang, Zhaoqun Jiao, Liqun Chen, Pingtian Yu, Yuping Shen, Huan Yang

   pp. 410–415 · DOI: 10.4103/pm.pm_596_18 · Published 16 May 2019

   Objective: In this study, we would like to find a rapid and accurate technology to identify medicinal leech. Materials and Methods: Three sets of species‑specific primer were designed, and polymerase chain reaction (PCR)…

8. Article

   Pentamethylquercetin Inhibited the Growth of Hepatic Ascitic Tumor Cell H22 by Improving Metabolic Environment and Aerobic Glycolysis in Monosodium Glutamate‑Induced Obese Mice

   Wenqi Gao, Xiao Xiao

   pp. 416–422 · DOI: 10.4103/pm.pm_605_18 · Published 16 May 2019

   Aim: We investigated the effects of pentamethylquercetin (PMQ) on the tumor growth in monosodium glutamate (MSG)‑induced obese mice. Materials and Methods: At the age of 5 weeks, control and MSG mice were, respectively, …

9. Article

   Angiopteris helferiana, a Fern with Great Potential Medicinal Value: Antiadipogenic, Anti‑Inflammatory, and Anti‑Diabetic Activity

   Ramakanta Lamichhane, Prakash Raj Pandeya, Kyung‑Hee Lee, Se‑Gun Kim, Dhan Raj Kandel, Hyun‑Ju Jung

   pp. 423–432 · DOI: 10.4103/pm.pm_430_18 · Published 16 May 2019

   Objective: In this study, we evaluated its anti‑oxidant, anti‑inflammatory, anti‑obesity, and antidiabetic activity in cell and animal mode. Materials and Methods: The rhizome of A. helferiana was extracted with methanol…

10. Article

    The Role of Total Flavone of Camellia on Cerebrovascular Vasopasm after Subarachnoid Hemorrhage in Rats

    Weizhuo Lu, Jiyue Wen

    pp. 433–437 · DOI: 10.4103/pm.pm_593_18 · Published 16 May 2019

    Background: This study was undertaken to explore the role of total flavones of Camellia (TFC) on the cerebrovascular dysfunction in rats after experimental subarachnoid hemorrhage (SAH). Materials and Methods: The contra…

11. Article

    Cytotoxicity, Protein Kinase Inhibitory Activity, and Docking Studies of Secondary Metabolites Isolated from Brownea grandiceps Jacq

    Ehab M. Mostafa, Arafa Musa, Mohamed A. Abdelgawad, Ehab A. Ragab

    pp. 438–442 · DOI: 10.4103/pm.pm_35_19 · Published 16 May 2019

    Objective: The objective was to study the cytotoxicity, kinase inhibitory activity, and docking of the isolated metabolites. Materials and Methods: Ultraviolet, nuclear magnetic resonance, and mass spectroscopy were used…

12. Article

    Antitumor and Immunoregulation Effects and Mechanism of N‑butanol Fraction from Zanthoxylum avicennae in H22 Mice

    Hong-Xin Cui, Fang-Rong Cheng, Nan-Nan Zheng, Shan-Shan Jia, Ke Yuan

    pp. 443–448 · DOI: 10.4103/pm.pm_251_18 · Published 16 May 2019

    Background: The aim of this study was to study the antitumor and immunomodulatory effects and its mechanism of the n‑butyl alcohol extract of the ethanol extracts in Zanthoxylum avicennae (Lam.) DC. for the mice with liv…

13. Article

    Determination of Trace Metal Concentrations in Different Parts of the Khat Varieties (Catha edulis) using Inductively Coupled Plasma‑Mass Spectroscopy Technique and their Human Exposure Assessment

    Mohammed Al Bratty, Waquar Ahsan, Hassan A. Alhazmi, Ibraheem M. Attafi, Ibrahim A. Khardali, Siddig I. Abdelwahab

    pp. 449–458 · DOI: 10.4103/pm.pm_658_18 · Published 16 May 2019

    Objective: Five most commonly used varieties of Khat namely Gaifi, Kofat, Jahasha, Faqarah Menjed, and Faqarah Aswad were selected for the study. Materials and Methods: Metal ion concentrations were determined using indu…

14. Article

    Chinese Native Medicinal Plant Euphorbiaceae Show Antitumor and Anti‑oxidant Features in Lewis Lung Cancer‑Bearing Mice

    Xiao‑Ming Zhao, Li‑Yuan Qu, Zhonghai Yan, Yun Yang, Ying Ma, Zhao‑Lun Dong, Zhen‑Ming Li, Meng‑Wen Li, Xin Wang, Fei Jiao

    pp. 459–465 · DOI: 10.4103/pm.pm_540_18 · Published 16 May 2019

    Objective: The present study aims to investigate the anticancer effects of Euphorbiaceae extract (EE) in vitro and in vivo, as well as the potential mechanisms. Materials and Methods: In the present study, 3‑(4,5‑dimethy…

15. Article

    Effect of Frost on Flavonol Glycosides Accumulation and Antioxidant Activities of Mulberry (Morus alba L.) Leaves

    Yu Xiaofeng, Zhao Shuang, Zhao Li, Wang Dan, Fan Xiaoman, Ouyang Zhen

    pp. 466–472 · DOI: 10.4103/pm.pm_493_18 · Published 16 May 2019

    Objective: We investigated the effect of frost on the accumulation of flavonoids and antioxidant activities of mulberry leaves. Materials and Methods: Liquid chromatography‑mass spectrometry and high‑performance liquid c…

16. Article

    Headspace–Solid‑Phase Microextraction Gas Chromatography Method to Quantify Thymus vulgaris Essential Oil in Polymeric Nanoparticles

    Lorena Lugo‑Estrada, Sergio Arturo Galindo‑Rodríguez, Luis Alejandro Pérez‑López, Noemí Waksman de Torres, Rocío Álvarez‑Román

    pp. 473–478 · DOI: 10.4103/pm.pm_277_18 · Published 16 May 2019

    Objective: To determine the chemical composition and physicochemical characterization of Tv‑EO as well as develop and validate a HSPM‑gas chromatography (GC) method for the analysis of Tv‑EO components encapsulated in NP…

17. Article

    Rapid and Simultaneous Analysis of Five Free Anthraquinone Contents in Rhubarb during the Stir‑Frying with Rice Wine Process by Near Infrared Reflectance Spectroscopy

    Xingyi Chen, Jintao Xue, Weiying Wang, Bihua Ma, Guo Huang, Yu Chen, Liming Ye

    pp. 479–486 · DOI: 10.4103/pm.pm_562_18 · Published 16 May 2019

    Objective: In this study, near infrared reflectance (NIR) spectroscopy was used to develop a new method for the rapid online analysis of five free anthraquinones (aloe‑emodin, rhein, emodin, chrysophanol, and physcion) d…

18. Article

    (‑)‑Epigallocatechin‑3‑Gallate Protects against Uric Acid‑Induced Endothelial Dysfunction in Human Umbilical Vein Endothelial Cells

    Hua Xie, Jianqin Sun, Yanqiu Chen, Min Zong, Danfeng Xu, Yan Wang

    pp. 487–493 · DOI: 10.4103/pm.pm_659_18 · Published 16 May 2019

    Background: Hyperuricemia is recently reported to be associated with hypertension, metabolic syndrome, and vascular damage. (‑)‑Epigallocatechin gallate (EGCG) is a major polyphenol component of green tea involving in po…

19. Article

    Anticancer Potential of Seed Extract and Pure Compound from Phoenix dactylifera on Human Cancer Cell Lines Ebtesam S. Al‑Sheddi Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

    Mohammed Ali, Ahmed Al-Ghamdi

    pp. 494–499 · DOI: 10.4103/pm.pm_623_18 · Published 16 May 2019

    Objectives: The objective is to isolate, characterize the major bioactive components and evaluate the cytotoxic activity of extract and isolated pure compound of P. dactylifera. Materials and Methods: P. dactylifera extr…

20. Article

    Polysaccharides from Radix Astragali Exert Immunostimulatory Effects to Attenuate the Dampness Stagnancy Due to Spleen Deficiency Syndrome

    Wenxiao Zhao, Lijun Chen, Ning Cui, Xuming Ji, Haiqiang Jiang, Tiantian Deng, Shijun Wang

    pp. 500–506 · DOI: 10.4103/pm.pm_503_18 · Published 16 May 2019

    Objective: The objective of the study is to investigate the potential mechanism of action of APS underlying attenuating water and fluid retention of rats with the DSSD syndrome in order to provide novel insights into the…

21. Article

    Inhibition of Oxidative Stress and Autophagy by Arbutin in Lipopolysaccharide‑Induced Myocardial Injury

    Beibei Zhang, Mengnan Zeng, Benke Li, Yangyang Wang, Yuxuan Kan, Shengchao Wang, Yijia Meng, Jiji Gao, Weisheng Feng, Xiaoke Zheng

    pp. 507–513 · DOI: 10.4103/pm.pm_552_18 · Published 16 May 2019

    Objective: The purpose of this study was to investigate the effect of Ar on LPS‑induced myocardial injury and its underlying mechanisms. Materials and Methods: The levels of tumor necrosis factor alpha, interleukin 6, ca…

22. Article

    Heat Stress Resistance Effect of Flavonoids from Penthorum chinense Pursh on Caenorhabditis elegans

    Shiling Feng, Liang Fu, Yujie Wang, Handong Wang, Ming Yuan, Yan Huang, Hongyu Yang, Chunbang Ding

    pp. 514–521 · DOI: 10.4103/pm.pm_500_18 · Published 16 May 2019

    Background: Excessive reactive oxygen species (ROS) may overwhelm antioxidative defense, which is implicated in the onset and progression of various diseases. Flavonoids extracted from Penthorum chinense Pursh have a rem…