Volume 9, Issue 2

Honey and Health: A Review of Recent Clinical Research

Saeed Samarghandian, Tahereh Farkhondeh, Fariborz Samini

pp. 121–127 · DOI: 10.4103/0974-8490.204647 · Published 1 April 2017

Honey is one of the most appreciated and valued natural products introduced to humankind since ancient times. Honey is used not only as a nutritional product but also in health described in traditional medicine and as an…

Pharmacognostic Specification, Chlorogenic Acid Content, and In vitro Antioxidant Activities of Lonicera japonica Flowering Bud

Chayanon Chaowuttikul, Chanida Palanuvej, Nijsiri Ruangrungsi

pp. 128–132 · DOI: 10.4103/pr.pr_117_16 · Published 1 April 2017

Background:Lonicera japonica Thunb. or Japanese Honeysuckle has been widely used in traditional medicine for antipyretic. Objective: To establish the pharmacognostic specification ofL. japonicaflowering bud in Thailand a…

Antiprotozoal Activities of Tiliroside and other Compounds from Sphaeralcea angustifolia (Cav.) G. Don

Fernando Calzada, Jose Correa Basurto, Elizabeth Barbosa, Claudia Velázquez, Normand García Hernández, RM Ordoñez Razo, David Mendez Luna, Lilian Yepez Mulia

pp. 133–137 · DOI: 10.4103/0974-8490.204644 · Published

Background: Sphaeralcea angustifolia (Malvaceae) is extensively used in Mexican traditional medicine for the treatment of gastrointestinal disorders such as diarrhea and dysentery. Objective: The current study was to val…

Preclinical Toxicological Evaluation of IDM01: The Botanical Composition of 4‑Hydroxyisoleucine‑ and Trigonelline‑based Standardized Fenugreek Seed Extract

Pallavi O Deshpande, Vishwaraman Mohan, Prasad Arvind Thakurdesai

pp. 138–150 · DOI: 10.4103/0974-8490.204649 · Published 1 April 2017

Objective: To evaluate acute oral toxicity (AOT), subchronic (90‑day repeated dose) toxicity, mutagenicity, and genotoxicity potential of IDM01, the botanical composition of 4‑hydroxyisoleucine‑ and trigonelline‑based st…

The Mealiness and Quality of Herbal Medicine: Licorice for Example

Xueying Liu, Weilong Hou, Deqiang Dou

pp. 151–155 · DOI: 10.4103/0974-8490.204642 · Published 1 April 2017

Background: The morphological identification is an effective and simple quality evaluation method in Chinese drugs, and the traits of mealiness and color were widely used in the commercial market of Chinese drugs.Objecti…

Effects of Ligusticum porteri (Osha) Root Extract on Human Promyelocytic Leukemia Cells

Khanh Nguyen, Jean Sparks, Felix Omoruyi

pp. 156–160 · DOI: 10.4103/0974-8490.204641 · Published 1 April 2021

Background: Ligusticum porteri roots have been traditionally used in folk medicine, but the scientific basis is unclear. Objective: To investigate the cytotoxicity, antioxidant, and immunomodulatory effects ofL. porteri …

Evaluation of Antioxidant, Hypolipidemic, and Antiatherogenic Property of Lycopene and Astaxanthin in Atherosclerosis‑induced Rats

Rajesh Kumar, Kartik Janardan Salwe, Manimekalai Kumarappan

pp. 161–167 · DOI: 10.4103/0974-8490.204654 · Published 1 April 2021

Background:Atherosclerosis is one of the major causes of morbidity and mortality in the world. Antioxidants play a major role in prophylaxis and prevention of progression and complications of atherosclerosis. Objective: …

Potential Roles of Kleinhovia hospita L. Leaf Extract in Reducing Doxorubicin Acute Hepatic, Cardiac and Renal Toxicities in Rats

Yulia Yusrini Djabir, M Aryadi Arsyad, Sartini Sartini, Subehan Lallo

pp. 168–173 · DOI: 10.4103/pr.pr_129_16 · Published 1 April 2021

Background:Doxorubicin (DOX) is a potent chemotherapy agent; however, its use may lead to cardiac, hepatic, and renal dysfunction. Kleinhovia hospita L extract contains antioxidant compounds that have been shown to reduc…

Neutralization of Inflammation by Inhibiting In vitro and In vivo Secretory Phospholipase A2 by Ethanol Extract of Boerhaavia diffusa L.

Aladahalli S Giresha, Siddanakoppalu N Pramod, AD Sathisha, KK Dharmappa

pp. 174–181 · DOI: 10.4103/0974-8490.204650 · Published 1 April 2021

Background:Inflammation is a normal and necessary prerequisite to healing of the injured tissues. Inflammation contributes to all disease process including immunity, vascular pathology, trauma, sepsis, chemical, and meta…

Hepatoprotective, Antihyperlipidemic, and Anti‑inflammatory Activity of Moringa oleifera in Diabetic‑induced Damage in Male Wistar Rats

Elizabeth I. Omodanisi, Yapo G Aboua, Novel N Chegou, Oluwafemi O Oguntibeju

pp. 182–187 · DOI: 10.4103/0974-8490.204651 · Published 1 April 2017

Background: The number of individuals with diabetes is increasing daily, and diabetes is presently estimated to affect about 422 million adults worldwide. Conventional drugs used to treat diabetes are not without severe …

Biological Effects of Hesperetin on Interleukin‑6/Phosphorylated Signal Transducer and Activator of Transcription 3 Pathway Signaling in Prostate Cancer PC3 Cells

Moein Shirzad, Esfandiar Heidarian, Pezhman Beshkar, Mostafa Gholami-Arjenaki

pp. 188–194 · DOI: 10.4103/0974-8490.204655 · Published 1 April 2021

Background:Interleukin-6 (IL-6) is a multifunctional glycoprotein that regulates the growth of some tumors, including prostate carcinomas due to signal transducer and activator of transcription 3 (STAT3), extracellular s…

Effect of Tamarindus indica L. and Manihot esculenta Extracts on Antibiotic‑resistant Bacteria

Zenon Machado Lima, Lenilson Santos da Trindade, Genelane Cruz Santana, Francine Ferreira Padilha, Marcelo da Costa Mendonca, Luiz Pereira da Costa, Jorge A Lopez, Maria Lucila Hernández Macedo

pp. 195–199 · DOI: 10.4103/0974-8490.204648 · Published 1 April 2021

Background:The chemical composition of plants used in traditional medicine exhibits biologically active compounds, such as tannins, flavonoids, and alkaloids and becomes a promising approach to treat microbial infections…

Protective Effect of Sorrel Extract on Adult Rats Treated by Carbon Tetrachloride

Abdullah Glil Alkushi

pp. 200–207 · DOI: 10.4103/0974-8490.204653 · Published 1 April 2021

Context:Heart, kidneys, and liver are the vital organs present in vertebrates and some other animals. They have a wide range of functions, such as maintaining homeostasis, detoxification, protein synthesis, and productio…

Botanical and Chemical Fingerprinting of Medicinal Roots of Justicia gendarussa Burm f.

Deepa Yadav, Mohd Salim Reshi, Chhavi Uthra, Sadhana Shrivastava, Nalini Srivastava, Sunil Kumar Koppala Narayana, Sangeeta Shukla

pp. 208–214 · DOI: 10.4103/0974-8490.204643 · Published 1 April 2021

Background:Justicia gendarussa Burm f. of family Acanthaceae is medicinally important herb used in the treatment of inflammatory disorders, asthma, hepatic injuries, pathogenic infection and also shows antiproliferative …

Rapid Development and Validation of Improved Reversed‑Phase High‑performance Liquid Chromatography Method for the Quantification of Mangiferin, a Polyphenol Xanthone Glycoside in Mangifera indica

P Naveen, HB Lingaraju, K Shyam Prasad

pp. 215–219 · DOI: 10.4103/0974-8490.204652 · Published 1 April 2021

Mangiferin, a polyphenolic xanthone glycoside from Mangifera indica, is used as traditional medicine for the treatment of numerous diseases. The present study was aimed to develop and validate a reversed-phase high-perfo…

Erratum: Bioactivity of Diterpens from the Ethyl Acetate Extract of Kingiodendron pinnatum Rox. Hams

pp. 220 · DOI: 10.4103/0974-8490.204656 · Published 1 April 2021

In the article titled, “Bioactivity of Diterpens from the Ethyl Acetate Extract of Kingiodendron pinnatum Rox. Hams” published in pages 287-291, issue 4, vol. 8 of Pharmacognosy Research,[1] the affiliation of the second…