Volume 16, Issue 68S

31 March 2020 · pp. 0–107 · 30 articles

Volume: 16
Issue: 68S
Published: 31 March 2020
Pages: 0–107
Articles: 30
Sections: 2
ISSN: ISSN: Print - 0973-1296, Online - 0976-4062
Journal: Pharmacogn. Mag.

Original Article Research Article

In this issue

Original Article

Article
Evaluation of the Anti‑proliferation and Anti‑migration Effects of Leucaena leucocephala and Dolichandrone serrulata Ethanolic Extracts against Human Cervical Cancer Cell Line
Ratikorn Chatchanayuenyong, Patcharawan Sujayanont
pp. S1–S7 · DOI: 10.4103/pm.pm_327_19 · Published 31 March 2020
Objectives: The aim of this study is to investigate the anti‑proliferative and anti‑migration effects of LL leaves and D. serrulata flowers ethanolic extracts against human cervical cancer cell line. Materials and Method…
Article
A Unified Method for Different Placental Products Species Identification
Tien-Lin Chang, Shang-Fang Wu, Der-Yuan Wang, Chih-Hung Huang
pp. S8–12 · DOI: 10.4103/pm.pm_296_19 · Published 31 March 2020
Objectives: To develop a universal species identification method for placental products. Materials and Methods: Fresh swine, cattle, goat, and frozen human placenta were used as references, while Placenta Hominis and pla…
Article
Phenolic Compounds of Heliotropium europaeum and their Biological Activities
Muneera S. M. Al‑Saleem, Lamya H. Al‑Wahaibi, Md Tabish Rehman, Mohamed F. AlAjmi, Rawiyah A. Alkahtani, Wael M. Abdel‑Mageed
pp. S108–S116 · DOI: 10.4103/pm.pm_376_19 · Published 31 March 2020
Objective: The objective of the study was to discover antioxidant phytochemical compounds in H. europaeum and assess their in vitro lipoxygenase (LOX)‑ and angiotensin‑converting enzyme (ACE) inhibitory activities. Mater…
Article
Effects of Anacyclus pyrethrum on Affective Behaviors and Memory during Withdrawal from Cigarette Smoke Exposure in Rats
Kenza Bezza, Jawad Laadraoui, Zineb El Gabbas, Mehdi Ait Laaradia, Sara Oufquir, Rachida Aboufatima, Issam Gharrassi, Abederrahman Chait
pp. S123–S132 · DOI: 10.4103/pm.pm_279_19 · Published 31 March 2020
Objectives: The aim of this study was to evaluate the behavioral effects of ethanolic extract of A. pyrethrum (EEAP) on smoking withdrawal in a rat model. Subjects and Methods: EEAP was administered orally at a dose of 2…
Article
Immunomodulatory Effect of Kaempferia parviflora against Cyclophosphamide‑Induced Immunosuppression in Swiss Albino Mice
Akoijam Ranjita Devi, Bibu John Kariyil, N. Mini Raj, G. H. Akhil, Dhanush Krishna Balakrishnan-Nair
pp. S13–S21 · DOI: 10.4103/pm.pm_233_19 · Published 31 March 2020
Objectives: The present study was carried out to evaluate the immunomodulatory effect of ethanolic extract of rhizomes of K. parviflora in cyclophosphamide‑induced immunosuppression in Swiss albino mice. Materials and Me…
Article
Amelioration of Cognitive Deficits by Spirulina platensis in L‑methionine‑Induced Rat Model of Vascular Dementia
Pian Wang, Yan Wang, Qingbin Zhang, Hongbo Zhang, Zheng Li, Xiaoying Liu, Lavleen Kaur, Manish Kumar
pp. S133–S141 · DOI: 10.4103/pm.pm_438_19 · Published 31 March 2020
Background: Vascular dementia (VaD) is an age‑associated highly prevalent brain disorder characterized by progressive cognitive insufficiency. Nutritional deprivation‑associated rise in homocysteine (HCy), dyslipidemia, …
Article
Wild- edible plants of Meghalaya State in India: Nutritional,
Minerals Minerals, Antinutritional Antinutritional, Vitamin Content, Toxicity Studies Tapan Seal, Kausik Chaudhuri, Basundhara Pillai, Shrabana Chakrabarti, Biswajit Auddy, Tanmoy Mondal
pp. S142–S151 · DOI: 10.4103/pm.pm_369_19 · Published 31 March 2020
Aim: The point of the present investigation planned to assess the nutritive value, minerals content, vitamin content, antinutritional properties, and toxicity studies in five wild‑consumable plants, for example, Begonia …
Article
Gastric Ulcer Healing Activity against Acidified Ethanol‑Induced Gastric Ulcer and Gastroprotective Mechanisms of Zingiber simaoense Rhizome Ethanol Extract in Rats
Chanyanuch Laprasert, Puongtip Kunanusorn, Ampai Panthong, Parirat Khonsung, Natthakarn Chiranthanut, Chaiyong Rujjanawate
pp. S152–S160 · DOI: 10.4103/pm.pm_389_19 · Published 31 March 2020
Objectives: This study aimed to investigate the gastric ulcer healing activity of Z. simaoense rhizome ethanol extract (ZSE) against acidified ethanol‑induced gastric ulcer and its possible gastroprotective mechanisms. M…
Article
A New Stilbene Derivative and Isolated Compounds from Bauhinia pottsii var. pottsii with their Anti‑alpha‑glucosidase Activity
Sathianpong Phoopha, Chatchai Wattanapiromsakul, Thanet Pitakbut, Sukanya Dej‑Adisai
pp. S161–S167 · DOI: 10.4103/pm.pm_433_19 · Published 31 March 2020
Objectives: Isolation of chemical constituents from B. pottsii var. pottsii and determination of their biological activity on alpha-glucosidase inhibition. Materials and Methods: Chromatographic techniques, enzymatic ass…
Article
Chronic Khat (Catha edulis) Chewing and Genotoxicity: The Role of Antioxidant Defense System and Oxidative Damage of DNA
Ashraf A. Hassan, Yahya Hasan Hobani, Neji Mosbah, Saif Elden Abdalla, Mohammad Zaino, Syam Mohan, Maged El‑Setouhy
pp. S168–S173 · DOI: 10.4103/pm.pm_455_19 · Published 31 March 2020
Objectives: Mainly, the objective of the study was to assess the risk of genotoxicity caused due to oxidative stress that may result from khat chewing among chronic chewers from Jazan Province of Saudi Arabia. Materials …
Article
Antiurolithic Evaluation of Cucurbita pepo Seeds Extract against Sodium Oxalate‑Induced Renal Calculi
Aisha Shehzad, Uzma Saleem, Muhammad Ajmal Shah, Celia Vargas-de la Cruz, Abdul Haleem Khan, Bashir Ahmad
pp. S174–S180 · DOI: 10.4103/pm.pm_166_19 · Published 31 March 2020
Objective: The present study was investigated to resolve the antiurolithic potential of methanol extract of C. pepo (MECP) seed against sodium oxalate‑induced renal calculi using both in vitro and in vivo models. Materia…
Article
Tumor Retardation and Immunomodulatory potential of Polyherbal Formulation HC9 in Mouse Melanoma Model
Snehal Suryavanshi, Kavita Shinde, Prerna Raina, Ruchika Kaul‑Ghanekar
pp. S181–S186 · DOI: 10.4103/pm.pm_289_19 · Published 31 March 2020
Background: HC9, a polyherbal formulation, is based on Stanyashodhana Kashaya (an Ayurvedic formulation) that is being prescribed by Ayurvedic physicians for the treatment of various disorders of mammary glands. We have …
Article
Secondary Metabolites and Pesticide Screening in Organic and Inorganic Tomatoes by Gas Chromatography–Mass Spectrometry and Liquid Chromatography/Tandem Mass Spectrometry
M. S. Shwetha, V. R. Sinija, Durgadevi M
pp. S187–S192 · DOI: 10.4103/pm.pm_76_19 · Published 31 March 2020
Objective: The objective of the study was to investigate the occurrence of pesticides and to analyze the secondary metabolite differences in selected organic and inorganic tomatoes (Variety: Sivam). Materials and Methods…
Article
The Toothache Plant (Acmella oleracea) Exhibits Anthelmintic Activity on Both Parasitic Tapeworms and Roundworms
P. B. Lalthanpuii, Zar Zokimi, Kholhring Lalchhandama
pp. S193–S198 · DOI: 10.4103/pm.pm_321_19 · Published 31 March 2020
Objectives: The objective of this study is to perform chemical analysis of the plant extract using gas chromatography‑mass spectrometry (GC‑MS) and to test the anthelmintic activity on intestinal helminths. Materials and…
Article
A Bioinformatics‑based Investigation to Screen and Analyze the Bioactivity of Piper longum Linn. Compounds as a Ground‑breaking Hostile to Antidiabetic Activity
Bikash Thakuria, Sorforaj Laskar, Samrat Adhikari
pp. S199–S205 · DOI: 10.4103/pm.pm_400_19 · Published 31 March 2020
As of today, the utilization of herbal medicines has taken up the pace in treating diseases. This is due to the fact that they have lower risk of adverse reactions. Numerous plants are being used traditionally to treat v…
Article
Topical Delivery of Curcumin and Caffeine Mixture‑Loaded Nanostructured Lipid Carriers for Effective Treatment of Psoriasis
Padmini Iriventi, N. Vishal Gupta
pp. S206–S217 · DOI: 10.4103/pm.pm_260_19 · Published 31 March 2020
Objective: The objective of the present study was to develop nanostructured lipid carriers (NLCs)‑based topical gels of CUR and caffeine combination for facilitated treatment of psoriasis. Materials and Methods: Preparat…
Article
Protective Effect of Withania somnifera on Nandrolone Decanoate‑Induced Biochemical Alterations and Hepatorenal Toxicity in Wistar Rats
Smitha Syamala Vasavan, Vijayakumar Jagadesan, Senthilkumar Sivanesan, Vijayaraghavan Rajagopalan
pp. S218–S223 · DOI: 10.4103/pm.pm_349_19 · Published 31 March 2020
Background: The genus <em>Cissus</em> (Vitaceae) is a large genus of about 350 species distributed in tropical and subtropical regions. <em>Cissus quadrangularis</em> L. is a well-known medicinal plant used in traditiona…
Article
Cytotoxic, α‑Glucosidase, and Antioxidant Activities of Flavonoid Glycosides Isolated from Flowers of Lotus lanuginosus Vent. (Fabaceae)
Mohamed Habib Oueslati, Jalloul Bouajila, Arbi Guetat, Fraj Al‑Gamdi, Fayçal Hichri
pp. S22–S27 · DOI: 10.4103/pm.pm_232_19 · Published 31 March 2020
Objective: The objectives of this study were to isolate secondary metabolites from the flowers of L. lanuginosus Vent., elucidate their structures, and evaluate their biological activities. Materials and Methods: Chromat…
Article
Antioxidant Activity and Enhanced Cytotoxicity of Aqueous Mucuna pruriens L. Leaf Extract by Doxorubicin on Different Human Cancer Cell Lines
Vesna Tumbas‑Šaponjac, Oke‑Oghene Philomena Akpoveso, Oluwatosin Imoleayo Oyeniran, Jelena Desančić, Dragana Četojević‑Simin
pp. S224–S228 · DOI: 10.4103/pm.pm_413_19 · Published 31 March 2020
Objective: The aim of this study was to evaluate the antioxidant and cytotoxic effect of an aqueous leaf extract of MP in different human cancer cell lines. This study also evaluated the enhanced cytotoxic effect of an a…
Article
Anticancer Effects of Piperine‑Free Piper nigrum Extract on Cholangiocarcinoma Cell Lines
Aman Tedasen, Araya Khoka, Siribhorn Madla, Somchai Sriwiriyajan, Potchanapond Graidist
pp. S28–S38 · DOI: 10.4103/pm.pm_288_19 · Published 31 March 2020
Objective: In this present study, we explored the anticancer effects of PFPE on cholangiocarcinoma (CCA). Materials and Methods: 3‑(4,5‑dimethyl thiazol‑2‑yl)‑2,5‑diphenyltetrazolium bromide assay was performed to analyz…
Article
Computer-Aided Box–Behnken Outlook Towards Optimization of Extraction of Lawsone from Mehendi Leaves
Lubna Abidin, Mohd. Mujeeb, Mohd. Aqil, Abul Kalam Najmi, Aftab Ahmad
pp. S39–S46 · DOI: 10.4103/pm.pm_345_19 · Published 31 March 2020
Objective: Comparing traditional and modern extraction modes for extraction of lawsone from L. inermis leaves and simultaneous use of response surface methodology for optimizing its extraction procedure. Materials and Me…
Article
Pharmacokinetic and Pharmacodynamic Interactions of Tinospora cordifolia Aqueous Extract and Hypoglycemic Drugs in Streptozotocin‑Induced Diabetes in Rats
Amisha Vora, Alice Varghese, Yusuf Kachwala, Ankit P Laddha, Manju Bhaskar, Jamal Akhtar, Pawan Yadav
pp. S47–S56 · DOI: 10.4103/pm.pm_272_19 · Published 31 March 2020
Aims: The aim of this study was to evaluate the potential pharmacokinetic (PK) and pharmacodynamic (PD) interactions of the aqueous extract of T. cordifolia (TCE) with metformin (MET), sitagliptin (SITA), and glibenclami…
Article
Mahanimbine‑Induced Neuroprotection via Cholinergic System and Attenuated Amyloidogenesis as well as Neuroinflammation in Lipopolysaccharides‑Induced Mice
Nur Syamimi Mohd Azahan, Vasudevan Mani, Kalavathy Ramasamy, Siong Meng Lim, Richard Muhammad Johari James, Mansour Alsharidah, Ahmad Alhowail, Abu Bakar Abdul Majeed
pp. S57–S63 · DOI: 10.4103/pm.pm_202_19 · Published 31 March 2020
Objective: The present study aimed to explore the neuroprotective potential of mahanimbine against lipopolysaccharides (LPS)‑induced memory deficit in Institute of Cancer Research (ICR) mice. Materials and Methods: Group…
Article
Rapid Identification of the Indigenous Medicinal Crop Cinnamomum osmophloeum from Various Adulterant Cinnamomum Species by DNA Polymorphism Analysis
Bo‑Cheng Yang, Meng‑Shiunn Lee, Fang‑Chun Sun, Heng‑Hsiang Chao, Wen‑Te Chang, Ming‑Kuem Lin, Hsi‑Jien Chen
pp. S64–S68 · DOI: 10.4103/pm.pm_267_19 · Published 31 March 2020
Objective: The purpose of this study was to develop a DNA‑based molecular method for rapid authentication of the indigenous Co and prevention of its adulteration. Materials and Methods: The internal transcribed spacer (I…
Article
Traditional Use of Ethnomedicinal Plants among People of Kapurthala District, Punjab, India
Jaskirat Kaur, Rajinder Kaur, Avinash Kaur Nagpal
pp. S69–S80 · DOI: 10.4103/pm.pm_311_19 · Published 31 March 2020
Background: Plant‑derived products have a vital biological role against various diseases. The present study was carried out to document and investigate the existing ethnomedicinal knowledge on local flora of Kapurthala d…
Article
Regulation of Pro‑Inflammatory Enzymes by the Dragon Fruits from Hylocereus undatus (Haworth) and Squalene ‑ its Major Volatile Constituents
Ibrahim M. S. Eldeen, Shin Y. Foong, Noraznawati Ismail, Keng C. Wong
pp. S81–S86 · DOI: 10.4103/pm.pm_271_19 · Published 31 March 2020
Objectives: To investigate anti‑inflammatory properties of the flesh and peel of Pitaya and to identify the major bioactive constituent(s). Materials and Methods: The flesh and the peel of the fruit were blended separate…
Article
Antiobesity Effects of Lycii Fructus in High‑Fat Diet/FructoseInduced Obese Rats
Junchao Yuan, Runfen Du, Zhuang Kang, Ben Niu, Opeyemi Joshua Olatunji, Yan Wang, Heng Su
pp. S87–S92 · DOI: 10.4103/pm.pm_276_19 · Published 31 March 2020
Objective: This study was aimed at investigating the effect of the ethyl acetate extract from Lycii fructus (ETLF) against high‑fat diet (HFD)/fructose‑induced obesity in rats. Materials and Methods: Obesity was induced …
Article
Antioxidant and Anti-inflammatory Potential of Cissus quadrangularis L. Stem Extracts
Cite this article as: Latif M, Umar MI, Rahim A, Khan SA, Fatima N, Hussain I
pp. S93–S98 · DOI: 10.4103/pm.pm_315_19 · Published 31 March 2020
Objectives: The current study was designed to investigate the phytochemical and biological properties of SM seed extract. Materials and Methods: Methanolic extract of SM (MESM) dried seeds was fractionated by column chro…
Article
Response Surface Optimization of Prodigiosin Production by Mutagen‑Treated Serratia marcescens in Different Growth Media
Sumaira Gul, Muhammad Aslam Shad, Rubina Arshad, Haq Nawaz, Aleema Ali, Asma Altaf, Tehreem Gul, Wafa Iqbal
pp. S99–107 · DOI: 10.4103/pm.pm_430_19 · Published 31 March 2020
Objectives: The study was planned to optimize the effect of ultravoilet (UV) light and acridine orange (AO), as mutagens and incubation time on prodigiosin production by S. marcescens in nutrient agar broth and peptone g…

Research Article

Article
Sandalwood Oil Neuroprotective Effects on Middle Cerebral Artery Occlusion Model of Ischemic Brain Stroke
Nancy Safwat Younis, Maged Elsayed Mohamed
pp. S117–S122 · DOI: 10.4103/pm.pm_398_19 · Published 31 March 2020
Objectives: The target of the current study was to inspect the pharmacological actions of sandalwood essential oil (SEO) through oxidative stress as well as inflammation pathways in mice exposed to middle cerebral artery…