Volume 13, Issue 49

Pharmacognosy Magazine-Completion of 12 years of successful publishing

Mueen Ahmed

pp. 1–1 · DOI: 10.4103/0973-1296.197631 · Published 2017

Antidermatophytic and Protease-inhibiting Activities of Zerumbone: A Natural Sesquiterpene from the Rhizome of Zingiber zerumbet (L.) Roscoe ex J.E; Smith

Madhavankutty Jyothilakshmi, Mathew Jyothis, Gokulanathan Nair Hari Narayanan, Mukalel Sankunni Latha

pp. 2–6 · DOI: 10.4103/0973-1296.197649 · Published 6 January 2017

Context: Due to increase in the number of patients with impaired immunity, incidence of dermatophytoses has increased considerably. Antidermatophytic agents with anti-inflammatory and protease-inhibiting activities will …

Wheatgrass Extract Ameliorates Hypoxia-induced Mucin Gene Expression in A549 cells

Ju hwan Sim, Moon-Hee Choi, Hyun-Jae Shin, Ji-Eun Lee

pp. 7–12 · DOI: 10.4103/0973-1296.197660 · Published 6 January 2017

Background: Wheatgrass is known to have antioxidant, antiaging, and anti-inflammatory effect. However, its protective effect against hypoxia is not yet evaluated. Objective: In this study, we evaluated the protective and…

Using UHPLC and UV-vis Fingerprint Method to Evaluate Substitutes for Swertia mileensis: An Endangered Medicinal Plant

Jie Li, Ji Zhang, Hang Jin, Yuan-Zhong Wang, Heng-Yu Huang

pp. 13–20 · DOI: 10.4103/0973-1296.197655 · Published 6 January 2017

Background: Millions of people are killed by viral hepatitis every year in the world, whereas many relevant medicines are too expensive to purchase. Swertia mileensis, a medicinal plant for hepatitis in the system of tra…

Nardostachys jatamansi Root Extract Modulates the Growth of IMR-32 and SK-N-MC Neuroblastoma Cell Lines Through MYCN Mediated Regulation of MDM2 and p53

Snehal Suryavanshi, Prerna Raina, Rashmi Deshpande, Ruchika Kaul-Ghanekar

pp. 21–4 · DOI: 10.4103/0973-1296.197645 · Published 6 January 2017

Aim: The present study evaluated the effect of ethanolic extract of Nardostachys jatamansi roots (NJet) on MYCN mediated regulation of expression of MDM2 and p53 proteins in neuroblastoma cell lines, IMR-32 and SK-N-MC. …

Antioxidant and Nephroprotective Activities of the Extract and Fractions of Homonoia riparia Lour

Seena kanniparambil Xavier, Shoja Muhammed Haneefa, Devkar Raviraj Anand, Picheswara Rao polo, Rajalekshmi Maheshwari, Chandrashekara Shastry Shreedhara, Manganahalli Manjunath Setty

pp. 25–30 · DOI: 10.4103/0973-1296.197647 · Published 6 January 2017

Background: Homonoia riparia is a plant, which is widely used in the indigenous system of medicine for the treatment of urolithiasis, renal disorders and inflammatory conditions. This is the first report on the antioxida…

Isolation and Characterisation of a Proanthocyanidin With Antioxidative, Antibacterial and Anti-Cancer Properties from Fern Blechnum orientale

How-Yee Lai, Yau-Yan Lim, Kah-Hwi Kim

pp. 31–37 · DOI: 10.4103/0973-1296.197659 · Published 6 January 2017

Background: Blechnum orientale Linn. (Blechnaceae), a fern, is traditionally used in the treatment of various ailments, such as skin diseases, stomach pain, urinary bladder complaints, and also as a female contraceptive.…

Specific PCR Identification between Peucedanum praeruptorum and Angelica decursiva and Identification between Them and Adulterant Using DNA Barcode

Bang-Xing Han, Yuan Yuan, Lu-Qi Huang, Qun Zhao, Ling-Ling Tan, Xiang-Wen Song, Xiao-Mei He, Tao Xu, Feng Liu, Jian Wang

pp. 38–45 · DOI: 10.4103/0973-1296.197658 · Published 6 January 2017

Background: The traditional Chinese medicine (TCM) Qianhu and Zihuaqianhu are the dried roots of Peucedanum praeruptorum and Angelica decursiva, respectively. Since the plant sources of Qianhu and Zihuaqianhu are more co…

Anticancer Potential of Nutraceutical Formulations in MNU-induced Mammary Cancer in Sprague Dawley Rats

Gummalla Pitchaiah, Annapurna Akula, Vishala Chandi

pp. 46–50 · DOI: 10.4103/0973-1296.197652 · Published 6 January 2017

Background: Nutraceuticals help in combating some of the major health problems of the century including cancer, and ‘nutraceutical formulations’ have led to the new era of medicine and health. Objective: To develop diffe…

Comparative Pharmacokinetic Profiles of Three Protoberberine-type Alkaloids from Raw and Bile-processed Rhizoma coptidis in Heat Syndrome Rats

Yuan Zi-min, Chen Yue, Gao Hui, Lv Jia, Chen Gui-rong, Jing Wang

pp. 51–7 · DOI: 10.4103/0973-1296.197632 · Published 6 January 2017

Background: The Bile-processed Rhizoma coptidis (BRC), which has a colder drug property than Rhizoma coptidis (RC), is widely used for the treatment of heat syndrome. We compared the pharmacokinetics of the protoberberin…

Chemical Components from Aloe and their Inhibition of Indoleamine 2, 3-dioxygenase

Ya Nan Sun, Lin Ying Li, Wei Li, Jong Seong Kang, Inkyu Hwang, Young Ho Kim

pp. 58–63 · DOI: 10.4103/0973-1296.197633 · Published 1 June 2017

Background: In Korea, Aloe is routinely ingested as a traditional medicine or as a component of health beverages. Objective: To research the inhibition of indoleamine 2, 3-dioxygenase (IDO) activities of components from …

Simultaneous Determination of Eight Phenolic Acids, Five Saponins and Four Tanshinones for Quality Control of Compound Preparations Containing Danshen-Sanqi Herb-pair by HPLC-DAD

Hong Yao, Xiaomei Huang, Shaoguang Li, Youjia Wu, Xinhua Lin, Peiying Shi

pp. 64–75 · DOI: 10.4103/0973-1296.197651 · Published 6 January 2017

Background: The herb-pair, Salviaemiltiorrhizae (Danshen, DS) and Panaxnotoginseng (Sanqi,SQ), often occurs in traditional Chinese medicine prescriptions used for the treatment of cardiovascular diseases in clinics in As…

Obtaining a Dry Extract from the Mikania laevigata Leaves with Potential for Antiulcer Activity

Mariana Viana Pinto, Ezequiane Machado Oliveira, Jose Luiz Rodrigues Martins, Jose Realino de Paula, Elson Alves Costa, Edemilson Cardoso da Conceição, Maria Teresa Freitas Bara

pp. 76–80 · DOI: 10.4103/0973-1296.197640 · Published 6 January 2017

Background: Mikania laevigata leaves are commonly used in Brazil as a medicinal plant. Objective: To obtain hydroalcoholic dried extract by nebulization and evaluate its antiulcerogenic potential. Materials and Methods: …

Anti-nociceptive Effect of 7-methoxy Coumarin from Eupatorium Triplinerve vahl (Asteraceae)

Binoy Varghese Cheriyan, Parimala Kadhirvelu, Jagan Nadipelly, Jaikumar Shanmugasundaram, Vijaykumar Sayeli, Viswanathan Subramanian

pp. 81–4 · DOI: 10.4103/0973-1296.197650 · Published 6 January 2017

Aim: To evaluate the anti-nociceptive activity of 7-methoxy coumarin isolated from ethyl acetate fraction of the alcoholic extract of Eupatorium triplinerve Vahl. Materials and Methods: The shade dried leaves of E. tripl…

Effect of Absolute From Hibiscus syriacus L. Flower on Wound Healing in Keratinocytes

Seok Won Yoon, Kang Pa Lee, Do-Yoon Kim, Dae Il Hwang, Kyung-Jong Won, Dae Won Lee, Hwan Myung Lee

pp. 85–9 · DOI: 10.4103/0973-1296.197644 · Published 6 January 2017

Background: Proliferation and migration of keratinocytes are essential for the repair of cutaneous wounds. Hibiscus syriacus L. has been used in Asian medicine; however, research on keratinocytes is inadequate. Objective…

Osteoblasts Proliferation and Differentiation Stimulating Activities of the Main Components of Epimedii folium

Mingming Liu, Haiyan Xu, Yong Ma, Jian Cheng, Zhen Hua, Guicheng Huang

pp. 90–4 · DOI: 10.4103/0973-1296.197654 · Published 6 January 2017

Background: Osteoporosis is a disease of bones that leads to an increased risk of fracture. Epimedii Folium is commonly used for treating bone fractures and joint diseases for thousands of years in China. Methods: This s…

Evaluate the Antigenotoxicity and Anticancer Role of β-Sitosterol by Determining Oxidative DNA Damage and the Expression of Phosphorylated Mitogen-activated Protein Kinases’, C-fos, C-jun, and Endothelial Growth Factor Receptor

Ramalingam Sharmila, Ganapathy Sindhu

pp. 95–101 · DOI: 10.4103/0973-1296.197634 · Published 6 January 2017

Background: Plant sterols are the major source of micronutrients and have not shown any obvious side effects in human. β-sitosterol is one of the most prevalent phytosterols which have been recorded in ancient medicinal …

Effects of Potassium Sulfate [K2SO4] on the Element Contents, Polyphenol Content, Antioxidant and Antimicrobial Activities of Milk Thistle [Silybum Marianum]

Gulsum Yaldiz

pp. 102–107 · DOI: 10.4103/0973-1296.197641 · Published 6 January 2017

Background: Silybum marianum L. (Milk thistle) is native to the Mediterranean basin and is now widespread throughout the world. It’s sprout is used as a herbal medicine for the treatment of liver disease for centuries. T…

Antioxidant and Hepatoprotective Potential of Phenol-Rich Fraction of Juniperus communis Linn. Leaves

Akash Ved, Amresh Gupta, Ajay Kumar Singh Rawat

pp. 108–13 · DOI: 10.4103/0973-1296.197648 · Published 6 January 2017

Background: Juniperus communis Linn. is an important plant in India traditional system of medicine which is widely used by different tribes in many countries. Objective: In the present study, the antioxidant, cytotoxic a…

Effects of Insecticidal Ketones Present in Mint Plants on GABAA Receptor from Mammalian Neurons

Mariela Eugenia Sánchez-Borzone, Leticia Delgado Marin, Daniel Asmed García

pp. 114–7 · DOI: 10.4103/0973-1296.197638 · Published 6 January 2017

Background: The genus Mentha, an important member of the Lamiaceae family, is represented by many species commonly known as mint. The insecticidal activity of Mentha oil and its main components has been tested and establ…

Therapeutic Effect of Dendrobium candidum on Lupus Nephritis in Mice

Qiang Wang, Peng Sun, Rui Wang, Xin Zhao

pp. 129–35 · DOI: 10.4103/0973-1296.197653 · Published 6 January 2017

Context: Dendrobium candidum (D.candimum) widely is a functional drug. The curative effect of D. candidum on lupus nephritis has been studied in vivo. Materials and Method: The DBA/2 and B6D2F1 mice were used for this in…

High Performance Liquid Chromatography-Diode Array Detector Method for the Simultaneous Determination of Five Compounds in the Pulp and Seed of Sea Buckthorn

Lu Zhao, E Wen, Halmuart Upur, Shuge Tian

pp. 136–40 · DOI: 10.4103/0973-1296.197656 · Published 6 January 2017

Context: Sea buckthorn (Hippophae rhamnoides L.) as a traditional Chinese medicinal plant has various uses in Xinjiang. Objective: A reversed-phase rapid-resolution liquid-chromatography method with diode array detector …

Antiprotozoal Constituents from Annona cherimola Miller, a Plant Used in Mexican Traditional Medicine for the Treatment of Diarrhea and Dysentery

Fernando Calzada, Jose Correa-Basurto, Elizabeth Barbosa, David Mendez-Luna, Lilian Yepez-Mulia

pp. 148–52 · DOI: 10.4103/0973-1296.197636 · Published 6 January 2017

Background: Annona cherimola Miller (Annonaceae) is a medicinal plant frequently recommended in Mexican traditional medicine for the treatment of gastrointestinal disorders such as diarrhea and dysentery. Objective: This…

Trichosanthes kirilowii Exerts Androgenic Activity via Regulation of PSA and KLK2 in 22Rv1 Prostate Cancer Cells

Soo-Jin Jeong, Ji-Yoon Choi, Mi-Sook Dong, Chang-Seob Seo, Hyeun-Kyoo Shin

pp. 153–8 · DOI: 10.4103/0973-1296.197657 · Published 6 January 2017

Background: The androgen comprises a group of hormones that play roles in male reproductive activity as well as personal characteristics. Objective: We investigated the androgenic activity of various herbal medicines in …

Technological Evaluation of Emulsions Containing The Volatile Oil from Leaves of Plectranthus Amboinicus Lour

Pablo Queiroz Lopes, Fabiola Bernardo Carneiro, Ana Letícia Braz de Sousa, Sócrates Golziodo Santos, Elquio Eleamen Oliveira, Luiz Alberto Lira Soares

pp. 159–67 · DOI: 10.4103/0973-1296.197646 · Published 6 January 2017

Background: Plectranthus amboinicus Lour is a species which is widespread throughout tropical countries where it is widely used against respiratory tract disorders such as bronchodilator, antitussive, and expectorant con…

Feeble Antipyretic, Analgesic, and Anti-inflammatory Activities were Found with Regular Dose 4’-O-β-D-Glucosyl-5-O-Methylvisamminol, One of the Conventional Marker Compounds for Quality Evaluation of Radix Saposhnikoviae

Jing-Ming Yang, Hua Jiang, Hong-Liang Dai, Zi-Wei Wang, Gui-Zhi Jia, Xiang-Cai Meng

pp. 168–74 · DOI: 10.4103/0973-1296.197637 · Published 6 January 2017

Introduction: 4’-O-β-D-glucosyl-5-O-methylvisamminol (GML) is a conventional marker compound for quality control of Radix Saposhnikoviae. Despite that, neither pharmacodynamic or pharmacokinetic information is available …

Rapid Analysis of Components in Coptis chinensis Franch by Ultra-Performance Liquid Chromatography with Quadrupole Time-of-Flight Mass Spectrometry

Peng-peng Tian, Xiao-xu Zhang, Hong-ping Wang, Pu-ling Li, Yu-xin Liu, Shao-jing Li

pp. 175–179 · DOI: 10.4103/0973-1296.197635 · Published 6 January 2017

Background: Coptis chinensis Franch is a traditional Chinese medical herb. Objective: In this article, ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was used to rapidly,…

Combinative Method Using Multi-components Quantitation and HPLC Fingerprint for Comprehensive Evaluation of Gentiana crassicaulis

Jiuhua Song, Fengzheng Chen, Jiang Liu, Yuanfeng Zou, Yun Luo, Xiaoyan Yi, Jie Meng, Xingfu Chen

pp. 180–187 · DOI: 10.4103/0973-1296.197639 · Published 1 June 2017

Background: Gentiana crassicaulis (粗茎秦艽, cū jīng qín jiāo) is an important traditional Chinese herb. Like other herbs, its chemical compounds vary greatly by the environmental and genetic factors, as a result, the qualit…

Green Biosynthesis, Characterization, In vitro Antidiabetic Activity, and Investigational Acute Toxicity Studies of Some Herbal-mediated Silver Nanoparticles on Animal Models

Kalakotla Shanker, Gottumukkala Krishna Mohan, Md. Ashwaq Hussain, Naradala Jayarambabu, Poka Lakshmi Pravallika

pp. 188–92 · DOI: 10.4103/0973-1296.197642 · Published 6 January 2017

Diabetes is a metabolic disorder characterized by hyperglycemia, altered carbohydrate, lipid and protein metabolism. In recent studies, Nanoscience and nanotechnology are blazing fields for researchers; for researchers; …

Cytotoxic Activities of Naturally Occurring Oleanane‑, Ursane‑, and Lupane‑type Triterpenes on HepG2 and AGS Cells

Heejung Yang, Hyun Woo Kim, Young Choong Kim, Sang Hyun Sung

pp. 118–122 · DOI: 10.4103/0973-1296.196308 · Published 6 January 2017

Background: It is well known that the naturally occurring modified triterpenes in plants have a wide diversity of chemical structures and biological functions. The lupane‑, oleanane‑, and ursane‑type triterpenes are the …

Vincamine Alleviates Amyloid‑β 25–35 Peptides‑induced Cytotoxicity in PC12 Cells

Jianfeng Han, Qiumin Qu, Jin Qiao, Jie Zhang

pp. 123–128 · DOI: 10.4103/0973-1296.196309 · Published 6 January 2017

Objective: Vincamine is a plant alkaloid used clinically as a peripheral vasodilator that increases cerebral blood flow and oxygen and glucose utilization by neural tissue to combat the effect of aging. The main purpose …

Depolarizing Effects of Daikenchuto on Interstitial Cells of Cajal from Mouse Small Intestine

Hyungwoo Kim, Hyun Jung Kim, Dongki Yang, Myeong Ho Jung, Byung Joo Kim

pp. 141–147 · DOI: 10.4103/0973-1296.196312 · Published 6 January 2017

Background: Daikenchuto (DKT; TJ‑100, TU‑100), a traditional herbal medicine, is used in modern medicine to treat gastrointestinal (GI) functional disorders. Interstitial cells of Cajal (ICCs) are the pacemaker cells of …

Quality‑by‑Design: Multivariate Model for Multicomponent Quantification in Refining Process of Honey

Xiaoying Li, Zhisheng Wu, Xin Feng, Shanshan Liu, Xiaojie Yu, Qun Ma, Yanjiang Qiao

pp. 193–198 · DOI: 10.4103/0973-1296.196310 · Published 6 January 2017

Objective: A method for rapid analysis of the refining process of honey was developed based on near-infrared (NIR) spectroscopy. Methods: Partial least square calibration models were built for the four components after t…